Search Results - "Boulet, Nathalie"
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Glucocorticoid-Induced Obesity Develops Independently of UCP1
Published in Cell reports (Cambridge) (07-05-2019)“…An excess of glucocorticoids leads to the development of obesity in both mice and humans, but the mechanism for this is unknown. Here, we determine the extent…”
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The Sexual Dimorphism of Human Adipose Depots
Published in Biomedicines (01-10-2022)“…The amount and the distribution of body fat exhibit trajectories that are sex- and human species-specific and both are determinants for health. The enhanced…”
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High doses of tyramine stimulate glucose transport in human fat cells
Published in Journal of physiology and biochemistry (01-05-2022)“…Among the dietary amines present in foods and beverages, tyramine has been widely studied since its excessive ingestion can cause catecholamine release and…”
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4
Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans
Published in JCI insight (26-03-2020)“…We hypothesized that skeletal muscle contraction produces a cellular stress signal, triggering adipose tissue lipolysis to sustain fuel availability during…”
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5
Oxytocin, social factors, and the expression of conditioned disgust (anticipatory nausea) in male rats
Published in Behavioural pharmacology (01-12-2016)“…Disgust has been proposed to have evolved as a means to rid the body and mouth of noxious substances and toxins, as well as to motivate and facilitate…”
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The Dietary Antioxidant Piceatannol Inhibits Adipogenesis of Human Adipose Mesenchymal Stem Cells and Limits Glucose Transport and Lipogenic Activities in Adipocytes
Published in International journal of molecular sciences (17-07-2018)“…Phenolic compounds are among the most investigated herbal remedies, as is especially the case for resveratrol. Many reports have shown its anti-aging…”
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Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes
Published in Molecules (Basel, Switzerland) (23-06-2021)“…Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous…”
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Human White and Brite Adipogenesis is Supported by MSCA1 and is Impaired by Immune Cells
Published in Stem cells (Dayton, Ohio) (01-04-2015)“…Obesity‐associated inflammation contributes to the development of metabolic diseases. Although brite adipocytes have been shown to ameliorate metabolic…”
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Isothermal microcalorimetry measures UCP1-mediated thermogenesis in mature brite adipocytes
Published in Communications biology (21-09-2021)“…The activation of thermogenesis in adipose tissue has emerged as an important target for the development of novel anti-obesity therapies. Using multi-well…”
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Subcutaneous Stromal Cells and Visceral Adipocyte Size Are Determinants of Metabolic Flexibility in Obesity and in Response to Weight Loss Surgery
Published in Cells (Basel, Switzerland) (09-11-2022)“…Adipose tissue (AT) expansion either through hypertrophy or hyperplasia is determinant in the link between obesity and metabolic alteration. The present study…”
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Past, Present and Future Anti-Obesity Effects of Flavin-Containing and/or Copper-Containing Amine Oxidase Inhibitors
Published in Medicines (Basel, Switzerland) (15-01-2019)“…Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and…”
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Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control
Published in Pharmaceuticals (Basel, Switzerland) (05-03-2020)“…Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic complications. The proposed mechanisms by which the atypical…”
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Methylamine Activates Glucose Uptake in Human Adipocytes Without Overpassing Action of Insulin or Stimulating its Secretion in Pancreatic Islets
Published in Medicines (Basel, Switzerland) (12-08-2019)“…: Methylamine, a natural soluble amine present in foods, is known to be a substrate of primary amine oxidase (PrAO) widely expressed in animal tissues…”
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Expression of the Adipocyte Progenitor Markers MSCA1 and CD36 is Associated With Adipose Tissue Function in Children
Published in The journal of clinical endocrinology and metabolism (01-02-2022)“…MSCA1 (mesenchymal stem cell antigen 1) and CD36 (cluster of differentiation 36) have been described as novel adipocyte progenitor markers in adults with a…”
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Network Analyses Reveal Negative Link Between Changes in Adipose Tissue GDF15 and BMI During Dietary-induced Weight Loss
Published in The journal of clinical endocrinology and metabolism (01-01-2022)“…Adipose tissue (AT) transcriptome studies provide holistic pictures of adaptation to weight and related bioclinical settings changes. To implement AT gene…”
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High doses of catecholamines activate glucose transport in human adipocytes independently from adrenoceptor stimulation or vanadium addition
Published in World journal of diabetes (15-01-2022)“…When combined with vanadium salts, catecholamines strongly activate glucose uptake in rat and mouse adipocytes. To test whether catecholamines activate glucose…”
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Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue
Published in Aging cell (01-03-2023)“…Senescence is a key event in the impairment of adipose tissue (AT) function with obesity and aging but the underlying molecular and cellular players remain to…”
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Cannabinoid 2 (CB2) receptor agonism reduces lithium chloride-induced vomiting in Suncus murinus and nausea-induced conditioned gaping in rats
Published in European journal of pharmacology (05-09-2016)“…We aimed to investigate the potential anti-emetic and anti-nausea properties of targeting the cannabinoid 2 (CB2) receptor. We investigated the effect of the…”
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The β 3 -adrenergic receptor is dispensable for browning of adipose tissues
Published in American journal of physiology: endocrinology and metabolism (01-06-2017)“…Brown and brite/beige adipocytes are attractive therapeutic targets to treat metabolic diseases. To maximally utilize their functional potential, further…”
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Effects of the amino acid derivatives, β-hydroxy-β-methylbutyrate, taurine, and N-methyltyramine, on triacylglycerol breakdown in fat cells
Published in Journal of physiology and biochemistry (01-08-2019)“…Various amino acid (AA) metabolites are used as supplements to facilitate metabolic control and enhance responsiveness of insulin-sensitive tissues…”
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