Search Results - "Boulay, JL"
-
1
P21 gene expression as an indicator for the activity of adenovirus-p53 gene therapy in non-small cell lung cancer patients
Published in Cancer gene therapy (01-09-2000)“…Alterations in the tumor suppressor gene p53 lead to impaired cell cycle control, allowing for the development and growth of tumors. To restore a loss of p53…”
Get full text
Journal Article -
2
The interleukin-4 family of lymphokines
Published in Current opinion in immunology (01-06-1992)“…Evidence has accumulated indicating that four T-cell derived lymphokines, interleukin-4, interleukin-5, granulocyte-macrophage colony stimulating factor and…”
Get more information
Journal Article -
3
Molecular Phylogeny within Type I Cytokines and Their Cognate Receptors
Published in Immunity (01-08-2003)“…Type I helical cytokines are ligands for receptors structurally related by a common sequence signature. Here we analyze the 27 ligands and 34 human type I…”
Get full text
Book Review Journal Article -
4
SMAD7 is a prognostic marker in patients with colorectal cancer
Published in International journal of cancer (20-04-2003)“…Chromosomal region 18q21 is frequently deleted in colorectal cancer (CRC) and is associated with poor prognosis. Potential tumor suppressor mechanisms altered…”
Get full text
Journal Article -
5
SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer
Published in British journal of cancer (09-09-2002)“…The gene for the transducer of transforming growth factor-beta/bone morphogenetic protein signalling SMAD4, a potential suppressor of colorectal…”
Get full text
Journal Article -
6
Amplification of SKI Is a Prognostic Marker in Early Colorectal Cancer
Published in Neoplasia (New York, N.Y.) (01-05-2004)“…BACKGROUND: Improved risk stratification of early colorectal cancer might help to better select patients for adjuvant treatment. Alterations in the…”
Get full text
Journal Article -
7
Echographic examination in isolated sites controlled from an expert center using a 2-D echograph guided by a teleoperated robotic arm
Published in Ultrasound in medicine & biology (01-07-2003)“…The objective of the present project was to design and validate a method for teleoperating (from an expert site) an echographic examination in an isolated…”
Get more information
Journal Article -
8
Prognostic and predictive relevance of microsatellite instability in colorectal cancer
Published in Oncology reports (01-07-2005)“…Microsatellite instability (MSI) is the phenotypic hallmark of a deficient DNA mismatch-repair system, observed in 10-20% of sporadic colorectal cancers (CRC)…”
Get more information
Journal Article -
9
STRAP Is a Strong Predictive Marker of Adjuvant Chemotherapy Benefit in Colorectal Cancer
Published in Neoplasia (New York, N.Y.) (01-11-2004)“…BACKGROUND: Molecular predictors for the effectiveness of adjuvant chemotherapy in colorectal cancer are of considerable clinical interest. To this aim, we…”
Get full text
Journal Article -
10
DCR3 locus is a predictive marker for 5‐fluorouracil‐based adjuvant chemotherapy in colorectal cancer
Published in International journal of cancer (20-11-2002)“…Adjuvant chemotherapy reduces the incidence of distant metastasis and increases survival of patients with colorectal cancer. However, predictive markers are…”
Get full text
Journal Article -
11
Gastrin releasing peptide-preferring bombesin receptors mediate growth of human renal cell carcinoma
Published in Journal of the American Society of Nephrology (01-08-2000)“…Bombesin-like peptides typically act as neurotransmitters along the brain-gut axis and as growth factors in various human tissues. The present study…”
Get full text
Journal Article -
12
Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer
Published in Oncology (01-01-2005)“…Chromosome 18q deletion has been described as a negative prognostic factor in colorectal cancer (CRC). The relationship between its supposed negative…”
Get more information
Journal Article -
13
Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer
Published in British journal of cancer (10-02-2003)“…Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic…”
Get full text
Journal Article -
14
CD8+ T cells can be primed in vitro to produce IL-4
Published in The Journal of immunology (1950) (15-03-1992)“…IL-4 production by T lymphocytes from naive mice in response to stimulation by plate-bound anti-CD3 is concentrated among CD4+ T cells. In vitro stimulation of…”
Get full text
Journal Article -
15
The Drosophila developmental gene snail encodes a protein with nucleic acid binding fingers
Published in Nature (London) (26-11-1987)“…Pattern formation in the Drosophila embryo requires the concerted expression of maternal and zygotic genes. At least nineteen genes, twelve of which are…”
Get full text
Journal Article -
16
SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer
Published in British journal of cancer (21-07-2003)“…CORRECTION TO:: British Journal of Cancer (2002) 87, 630-634. doi:10.1038/sj.bjc.6600511…”
Get full text
Journal Article -
17
Gene dosage by quantitative real-time PCR
Published in BioTechniques (01-08-1999)Get full text
Journal Article -
18
Protein technologies and commercial enzymes
Published in Current opinion in biotechnology (01-08-1999)Get full text
Journal Article -
19
Combined copy status of 18q21 genes in colorectal cancer shows frequent retention of SMAD7
Published in Genes chromosomes & cancer (01-07-2001)“…Deletions of chromosome band 18q21 appear with very high frequency in a variety of carcinomas, especially in colorectal cancer. Potent tumor suppressor genes…”
Get full text
Journal Article -
20
The interleukin-4-related lymphokines and their binding to hematopoietin receptors
Published in The Journal of biological chemistry (15-10-1992)“…Much of the regulatory activity of T lymphocytes is mediated by a potent set of small proteins, often referred to as lymphokines. Lymphokines act on virtually…”
Get full text
Journal Article