Search Results - "Boulard, Olivier"

Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model by Kirchberger, Stefanie, Royston, Daniel J, Boulard, Olivier, Thornton, Emily, Franchini, Fanny, Szabady, Rose L, Harrison, Oliver, Powrie, Fiona

“…Patients with inflammatory bowel disease (IBD) have an increased risk of colon cancer. However, the immune cells and cytokines that mediate the transition from…”
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Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses by Hrdý, Jiří, Alard, Jeanne, Couturier-Maillard, Aurelie, Boulard, Olivier, Boutillier, Denise, Delacre, Myriam, Lapadatescu, Carmen, Cesaro, Annabelle, Blanc, Philippe, Pot, Bruno, Ryffel, Bernhard, Chamaillard, Mathias, Grangette, Corinne

“…Crohn’s disease is linked to a decreased diversity in gut microbiota composition as a potential consequence of an impaired anti-microbial response and an…”
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The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt + Treg and PD-1 blockade efficacy by Paz Del Socorro, Thomas, Oka, Kentaro, Boulard, Olivier, Takahashi, Motomichi, Poulin, Lionel Franz, Hayashi, Atsushi, Chamaillard, Mathias

“…Immune checkpoint inhibitors (ICI) have been positioned as a standard of care for patients with advanced non-small-cell lung carcinomas (NSCLC). A pilot…”
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Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease by Asquith, Mark J, Boulard, Olivier, Powrie, Fiona, Maloy, Kevin J

“…Background & Aims Toll-like receptors (TLR) are innate immune receptors involved in recognition of the intestinal microflora; they are expressed by numerous…”
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Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens by Normand, Sylvain, Waldschmitt, Nadine, Neerincx, Andreas, Martinez-Torres, Ruben Julio, Chauvin, Camille, Couturier-Maillard, Aurélie, Boulard, Olivier, Cobret, Laetitia, Awad, Fawaz, Huot, Ludovic, Ribeiro-Ribeiro, Andre, Lautz, Katja, Ruez, Richard, Delacre, Myriam, Bondu, Clovis, Guilliams, Martin, Scott, Charlotte, Segal, Anthony, Amselem, Serge, Hot, David, Karabina, Sonia, Bohn, Erwin, Ryffel, Bernhard, Poulin, Lionel F., Kufer, Thomas A., Chamaillard, Mathias

“…Mutations in the nucleotide-binding oligomerization domain protein 12 (NLRP12) cause recurrent episodes of serosal inflammation. Here we show that NLRP12…”
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NOD2 in monocytes negatively regulates macrophage development through TNFalpha by Chauvin, Camille, Alvarez-Simon, Daniel, Radulovic, Katarina, Boulard, Olivier, Laine, William, Delacre, Myriam, Waldschmitt, Nadine, Segura, Elodie, Kluza, Jérome, Chamaillard, Mathias, Poulin, Lionel F

“…It is believed that intestinal recruitment of monocytes from Crohn's Disease (CD) patients who carry NOD2 risk alleles may repeatedly give rise to recruitment…”
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Loss of NOD2 in macrophages improves colitis and tumorigenesis in a lysozyme-dependent manner by Chauvin, Camille, Radulovic, Katarina, Boulard, Olivier, Delacre, Myriam, Waldschmitt, Nadine, Régnier, Paul, Legris, Gauthier, Bouchez, Clément, Sleimi, Mohamed-Yassine, Rosenstiel, Philip, Darrasse-Jèze, Guillaume, Chamaillard, Mathias, Poulin, Lionel F.

“…BackgroundCrohn's disease (CD) is a complex and poorly understood myeloid-mediated disorder. Genetic variants with loss of function in the NOD2 gene confer an…”
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Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation by Boulard, Olivier, Kirchberger, Stefanie, Royston, Daniel J, Maloy, Kevin J, Powrie, Fiona M

“…Chronic inflammation of the intestine has been associated with an elevated risk of developing colorectal cancer. Recent association studies have highlighted…”
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The colibactin-producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance by de Oliveira Alves, Nilmara, Dalmasso, Guillaume, Nikitina, Darja, Vaysse, Amaury, Ruez, Richard, Ledoux, Lea, Pedron, Thierry, Bergsten, Emma, Boulard, Olivier, Autier, Lora, Allam, Sofian, Motreff, Laurence, Sauvanet, Pierre, Letourneur, Diane, Kashyap, Pragya, Gagnière, Johan, Pezet, Denis, Godfraind, Catherine, Salzet, Michel, Lemichez, Emmanuel, Bonnet, Mathilde, Najjar, Imène, Malabat, Christophe, Monot, Marc, Mestivier, Denis, Barnich, Nicolas, Yadav, Pankaj, Fournier, Isabelle, Kennedy, Sean, Mettouchi, Amel, Bonnet, Richard, Sobhani, Iradj, Chamaillard, Mathias

“…Intratumoral bacteria flexibly contribute to cellular and molecular tumor heterogeneity for supporting cancer recurrence through poorly understood mechanisms…”
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Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis by Muharram, Ghaffar, Thépaut, Marion, Lobert, Pierre-Emmanuel, Grandjean, Teddy, Boulard, Olivier, Delacre, Myriam, Wakeford, Emmrich, Wheeler, Richard, Poulin, Lionel Franz, Boneca, Ivo Gomperts, Lafont, Frank, Michallet, Marie-Cécile, Hober, Didier, Cadwell, Ken, Chamaillard, Mathias

“…Over 90% of epidemic non-bacterial gastroenteritis are caused by human noroviruses (NoVs), which persist in a substantial subset of people allowing their…”
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Long-Term Overconsumption of Fat and Sugar Causes a Partially Reversible Pre-inflammatory Bowel Disease State by Arnone, Djésia, Vallier, Marie, Hergalant, Sébastien, Chabot, Caroline, Ndiaye, Ndeye Coumba, Moulin, David, Aignatoaei, Anda-Maria, Alberto, Jean-Marc, Louis, Huguette, Boulard, Olivier, Mayeur, Camille, Dreumont, Natacha, Peuker, Kenneth, Strigli, Anne, Zeissig, Sebastian, Hansmannel, Franck, Chamaillard, Matthias, Kökten, Tunay, Peyrin-Biroulet, Laurent

“…Nutrition appears to be an important environmental factor involved in the onset of inflammatory bowel diseases (IBD) through yet poorly understood biological…”
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The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut by Ramadan, Rana, Wouters, Valérie M., van Neerven, Sanne M., de Groot, Nina E., Garcia, Tania Martins, Muncan, Vanessa, Franklin, Olivia D., Battle, Michelle, Carlson, Karen Sue, Leach, Joshua, Sansom, Owen J., Boulard, Olivier, Chamaillard, Mathias, Vermeulen, Louis, Medema, Jan Paul, Huels, David J.

“…The rapid renewal of the epithelial gut lining is fuelled by stem cells that reside at the base of intestinal crypts. The signal transduction pathways and…”
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TLR2-independent induction and regulation of chronic intestinal inflammation by Boulard, Olivier, Asquith, Mark J, Powrie, Fiona, Maloy, Kevin J

“…Interactions between the intestinal microflora and host innate immune receptors play a critical role in intestinal homeostasis. Several studies have shown that…”
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Mapping Non–Class II H2-Linked Loci for Type 1 Diabetes in Nonobese Diabetic Mice by DERUYTTER, Nathalie, BOULARD, Olivier, GARCHON, Henri-Jean

“…Mapping Non–Class II H2-Linked Loci for Type 1 Diabetes in Nonobese Diabetic Mice Nathalie Deruytter , Olivier Boulard and Henri-Jean Garchon INSERM U580 and…”
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An Interval Tightly Linked to but Distinct From the H2 Complex Controls Both Overt Diabetes (Idd16) and Chronic Experimental Autoimmune Thyroiditis (Ceat1) in Nonobese Diabetic Mice by BOULARD, Olivier, DAMOTTE, Diane, DERUYTTER, Nathalie, FLUTEAU, Guy, CARNAUD, Claude, GARCHON, Henri-Jean

“…An Interval Tightly Linked to but Distinct From the H2 Complex Controls Both Overt Diabetes ( Idd16 ) and Chronic Experimental Autoimmune Thyroiditis ( Ceat1 )…”
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Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice by LAMHAMEDI-CHERRADI, Salah-Eddine, BOULARD, Olivier, GONZALEZ, Cristina, KASSIS, Najiby, DAMOTTE, Diane, ELOY, Laure, FLUTEAU, Guy, LEVI-STRAUSS, Matthieu, GARCHON, Henri-Jean

“…Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice Salah-Eddine Lamhamedi-Cherradi , Olivier Boulard , Cristina Gonzalez , Najiby Kassis ,…”
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The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt + Treg and PD-1 blockade efficacy by Paz del Socorro, Thomas, Oka, Kentaro, Boulard, Olivier, Takahashi, Motomichi, Poulin, Lionel Franz, Hayashi, Atsushi, Chamaillard, Mathias

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A Protective Role of NOD2 on Oxazolone-induced Intestinal Inflammation Through IL-1β-mediated Signalling Pathway by Secher, Thomas, Couturier, Aurélie, Huot, Ludovic, Bouscayrol, Helene, Grandjean, Teddy, Boulard, Olivier, Hot, David, Ryffel, Bernhard, Chamaillard, Mathias

“…NOD2 has emerged as a critical player in the induction of both Th1 and Th2 responses for potentiation and polarisation of antigen-dependent immunity…”
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A protective role of NOD2 on oxazolone-induced intestinal inflammation through IL-1beta-mediated signaling pathway by Secher, Thomas, Couturier, Aurélie, Huot, Ludovic, Bouscayrol, Hélène, Grandjean, Teddy, Boulard, Olivier, Hot, David, Ryffel, B., Chamaillard, Mathias

“…Background and AimsNOD2 has emerged as a critical player in the induction of both Th1 and Th2 responses for potentiation and polarisation of antigen-dependent…”
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Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis by Muharram, Ghaffar, Thépaut, Marion, Lobert, Pierre-Emmanuel, Grandjean, Teddy, Boulard, Olivier, Delacre, Myriam, Wakeford, Emmrich, Wheeler, Richard, Poulin, Lionel Franz, Boneca, Ivo Gomperts, Lafont, Frank, Michallet, Marie-Cécile, Hober, Didier, Cadwell, Ken, Chamaillard, Mathias

“…Over 90% of epidemic non-bacterial gastroenteritis are caused by human noroviruses (NoVs), which persist in a substantial subset of people allowing their…”
Get full text