Search Results - "Boukes, Gerhardt J"

The apoptotic and autophagic properties of two natural occurring prodrugs, hyperoside and hypoxoside, against pancreatic cancer cell lines by Boukes, Gerhardt J, van de Venter, Maryna

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Rooperol as an antioxidant and its role in the innate immune system: An in vitro study by Boukes, Gerhardt J., van de Venter, Maryna

“…Biologically active rooperol is formed when the glucose subunits of the nontoxic glycoside, hypoxoside, are cleaved by β-glucosidase. Hypoxoside is isolated…”
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Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy by LINDNER, Andreas U, CONCANNON, Caoimhin G, KAY, Elaine W, HECTOR, Suzanne, GREEN, Douglas R, HUBER, Heinrich J, PREEN, Jochen H. M, BOUKES, Gerhardt J, CANNON, Mary D, LLAMBI, Fabien, RYAN, Deborah, BOLAND, Karen, KEHOE, Joan, MCNAMARA, Deborah A, MURRAY, Frank

“…Apoptotic desensitization is a hallmark of cancer cells, but present knowledge of molecular systems controlling apoptosis has yet to provide significant…”
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Systems Analysis of Cancer Cell Heterogeneity in Caspase-dependent Apoptosis Subsequent to Mitochondrial Outer Membrane Permeabilization by Schmid, Jasmin, Dussmann, Heiko, Boukes, Gerhardt J., Flanagan, Lorna, Lindner, Andreas U., O'Connor, Carla L., Rehm, Markus, Prehn, Jochen H.M., Huber, Heinrich J.

“…Deregulation of apoptosis is a hallmark of carcinogenesis. We here combine live cell imaging and systems modeling to investigate caspase-dependent apoptosis…”
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Quantitative and qualitative analysis of sterols/sterolins and hypoxoside contents of three Hypoxis (African potato) spp by Gerhardt, J Boukes, Maryna, van de Venter, Vaughan, Oosthuizen

“…The glycoside, hypoxoside, identified and isolated from the corms of the African potato (Hypoxis hemerocallidea) has shown promising anticancer activities. The…”
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Cell survival or apoptosis: rooperol's role as anticancer agent by Boukes, Gerhardt J, Daniels, Brodie B, Albrecht, Carl F, van de Venter, Maryna

“…Nontoxic hypoxoside, isolated from Hypoxis, is converted to cytotoxic rooperol in the presence of beta-glucosidase. In this study, we investigated rooperol's…”
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Investigation of the inhibition of respiratory bacterial pathogens and HIV-1 enzymes by twenty-one South African mushroom species by Didloff, Jenske, Boukes, Gerhardt J., van de Venter, Maryna, Viljoen, Bennie, Lee, Michael, Blom, Candice, Dwyer, Rebecca A., Govender, Sharlene

“…•Medicinal properties (antibacterial- and anti-HIV-1 activities) of South African mushroom species.•Rhodofomitopsis lilacinogilva and Pisolithus tinctorius…”
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In vitro modulation of the innate immune response and phagocytosis by three Hypoxis spp. and their phytosterols by Boukes, Gerhardt J., Van de Venter, Maryna

“…Hypoxis forms an important part of South African traditional medicine. Crude Hypoxis extracts and hypoxoside have extensively been investigated for its…”
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