Search Results - "Boukens, Bastiaan J. D."

Identifying the evolutionary building blocks of the cardiac conduction system by Jensen, Bjarke, Boukens, Bastiaan J D, Postma, Alex V, Gunst, Quinn D, van den Hoff, Maurice J B, Moorman, Antoon F M, Wang, Tobias, Christoffels, Vincent M

“…The endothermic state of mammals and birds requires high heart rates to accommodate the high rates of oxygen consumption. These high heart rates are driven by…”
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Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius) by Boukens, Bastiaan J D, Joyce, William, Kristensen, Ditte Lind, Hooijkaas, Ingeborg, Jongejan, Aldo, Wang, Tobias, Jensen, Bjarke

“…Ectothermic vertebrates experience daily changes in body temperature, and anecdotal observations suggest these changes affect ventricular repolarization such…”
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The sodium channel NaV1.5 impacts on early murine embryonic cardiac development, structure and function in a non‐electrogenic manner by Marchal, Gerard A., Verkerk, Arie O., Mohan, Rajiv A., Wolswinkel, Rianne, Boukens, Bastiaan J. D., Remme, Carol Ann

“…Aim The voltage‐gated sodium channel NaV1.5, encoded by SCN5A, is essential for cardiac excitability and ensures proper electrical conduction. Early embryonic…”
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Developmental Basis for Electrophysiological Heterogeneity in the Ventricular and Outflow Tract Myocardium As a Substrate for Life-Threatening Ventricular Arrhythmias by Boukens, Bastiaan J.D, Christoffels, Vincent M, Coronel, Ruben, Moorman, Antoon F.M

“…Reentry is the main mechanism of life-threatening ventricular arrhythmias, including ventricular fibrillation and tachycardia. Its occurrence depends on the…”
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The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi by Hovius, Joppe W R, Bijlsma, Maarten F, van der Windt, Gerritje J W, Wiersinga, W Joost, Boukens, Bastiaan J D, Coumou, Jeroen, Oei, Anneke, de Beer, Regina, de Vos, Alex F, van 't Veer, Cornelis, van Dam, Alje P, Wang, Penghua, Fikrig, Erol, Levi, Marcel M, Roelofs, Joris J T H, van der Poll, Tom

“…The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however,…”
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Autonomic control over myocardial function in vitro: Evaluation of current and future clinical therapies in a nonclinical setting by Blok, Michiel, Jongbloed, Monique R. M., Boukens, Bastiaan J. D.

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Single‐site neural tube closure in human embryos revisited by de Bakker, Bernadette S., Driessen, Stan, Boukens, Bastiaan J.D., van den Hoff, Maurice J.B., Oostra, Roelof‐Jan

“…Since the multi‐site closure theory was first proposed in 1991 as explanation for the preferential localizations of neural tube defects, the closure of the…”
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The TMEM43 S358L mutation affects cardiac, small intestine, and metabolic homeostasis in a knock-in mouse model by Orgil, Buyan-Ochir, Munkhsaikhan, Undral, Pierre, Joseph F, Li, Ning, Xu, Fuyi, Alberson, Neely R, Johnson, Jason N, Wetzel, Glenn T, Boukens, Bastiaan J D, Lu, Lu, Towbin, Jeffrey A, Purevjav, Enkhsaikhan

“…The transmembrane protein 43 (TMEM43/LUMA) p.S358L mutation causes arrhythmogenic cardiomyopathy named as ARVC5, a fully penetrant disease with high risk of…”
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The electrocardiogram of vertebrates: Evolutionary changes from ectothermy to endothermy by Boukens, Bastiaan J.D., Kristensen, Ditte L., Filogonio, Renato, Carreira, Laura B.T., Sartori, Marina R., Abe, Augusto S., Currie, Shannon, Joyce, William, Conner, Justin, Opthof, Tobias, Crossley, Dane A., Wang, Tobias, Jensen, Bjarke

“…The electrocardiogram (ECG) reveals that heart chamber activation and repolarization are much faster in mammals and birds compared to ectothermic vertebrates…”
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Mechanism of ventricular premature beats elicited by left stellate ganglion stimulation during acute ischaemia of the anterior left ventricle by Boukens, Bastiaan J D, Dacey, Michael, Meijborg, Veronique M F, Janse, Michiel J, Hadaya, Joseph, Hanna, Peter, Swid, M Amer, Opthof, Tobias, Ardell, Jeffrey L, Shivkumar, Kalyanam, Coronel, Ruben

“…Abstract Aims Enhanced sympathetic activity during acute ischaemia is arrhythmogenic, but the underlying mechanism is unknown. During ischaemia, a diastolic…”
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The end of the unique myocardial band: Part II. Clinical and functional considerations by MacIver, David H, Partridge, John B, Agger, Peter, Stephenson, Robert S, Boukens, Bastiaan J D, Omann, Camilla, Jarvis, Jonathan C, Zhang, Henggui

“…Two of the leading concepts of mural ventricular architecture are the unique myocardial band and the myocardial mesh model. We have described, in an…”
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Stellate ganglion stimulation causes spatiotemporal changes in ventricular repolarization in pig by Meijborg, Veronique M.F., Boukens, Bastiaan J.D., Janse, Michiel J., Salavatian, Siamak, Dacey, Michael J., Yoshie, Koji, Opthof, Tobias, Swid, Mohammed Amer, Hoang, Jonathan D., Hanna, Peter, Ardell, Jeffrey, Shivkumar, Kalyanam, Coronel, Ruben

“…Dispersion in ventricular repolarization is relevant for arrhythmogenesis. The purpose of this study was to determine the spatiotemporal effects of sympathetic…”
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The sodium channel Na V 1.5 impacts on early murine embryonic cardiac development, structure and function in a non-electrogenic manner by Marchal, Gerard A, Verkerk, Arie O, Mohan, Rajiv A, Wolswinkel, Rianne, Boukens, Bastiaan J D, Remme, Carol Ann

“…The voltage-gated sodium channel Na 1.5, encoded by SCN5A, is essential for cardiac excitability and ensures proper electrical conduction. Early embryonic…”
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Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice by Aanhaanen, Wim T J, Boukens, Bastiaan J D, Sizarov, Aleksander, Wakker, Vincent, de Gier-de Vries, Corrie, van Ginneken, Antoni C, Moorman, Antoon F M, Coronel, Ruben, Christoffels, Vincent M

“…Ventricular preexcitation, a feature of Wolff-Parkinson-White syndrome, is caused by accessory myocardial pathways that bypass the annulus fibrosus. This…”
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Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction by Lockhart, Marie M, Boukens, Bastiaan J D, Phelps, Aimee L, Brown, Christina-Lin M, Toomer, Katelynn A, Burns, Tara A, Mukherjee, Rupak D, Norris, Russell A, Trusk, Thomas C, van den Hoff, Maurice J B, Wessels, Andy

“…Recent studies using mouse models for cell fate tracing of epicardial derived cells (EPDCs) have demonstrated that at the atrioventricular (AV) junction EPDCs…”
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Evolution of the Sinus Venosus from Fish to Human by Jensen, Bjarke, Boukens, Bastiaan, Wang, Tobias, Moorman, Antoon, Christoffels, Vincent

“…The sinus venosus, the cardiac chamber upstream of the (right) atrium, is a severely underinvestigated structure. Yet, its myocardium harbors the cardiac…”
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The sodium channel NaV 1.5 impacts on early murine embryonic cardiac development, structure and function in a non-electrogenic manner by Marchal, Gerard A, Verkerk, Arie O, Mohan, Rajiv A, Wolswinkel, Rianne, Boukens, Bastiaan J D, Remme, Carol Ann

“…AIMThe voltage-gated sodium channel NaV 1.5, encoded by SCN5A, is essential for cardiac excitability and ensures proper electrical conduction. Early embryonic…”
Get full text

The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi: e1000447 by Hovius, Joppe WR, Bijlsma, Maarten F, Windt, W vander, Wiersinga, W Joost, Boukens, Bastiaan JD, Coumou, Jeroen, Oei, Anneke, Beer, Regina de, Vos, Alex Fde, Veer, t, Dam, Alje Pvan, Wang, Penghua, Fikrig, Erol, Levi, Marcel M, Roelofs, J TH, Poll, Tom vander

“…The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however,…”
Get full text