Search Results - "Bouhassira, Eric E."
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Erratum to: Stem cell factor and erythropoietin-independent production of cultured reticulocytes
Published in Haematologica (Roma) (01-11-2024)Get full text
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Stem cell factor and erythropoietin-independent production of cultured reticulocytes
Published in Haematologica (Roma) (11-04-2024)“…Cultured reticulocytes can supplement transfusion needs and offer promise for drug delivery and immune tolerization. They can be produced from induced…”
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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites
Published in Proceedings of the National Academy of Sciences - PNAS (30-11-2021)“…Common fragile sites (CFSs) are difficult-to-replicate genomic regions that form gaps and breaks on metaphase chromosomes under replication stress. They are…”
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High-resolution mapping of h1 linker histone variants in embryonic stem cells
Published in PLoS genetics (01-04-2013)“…H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d…”
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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability
Published in Nature communications (22-10-2022)“…ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis. The three known ASAR genes are located on human…”
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Autophagy Driven by a Master Regulator of Hematopoiesis
Published in Molecular and Cellular Biology (01-01-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Globin switches in yolk sac–like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells
Published in Blood (15-02-2008)“…We have previously shown that coculture of human embryonic stem cells (hESCs) for 14 days with immortalized fetal hepatocytes yields CD34+ cells that can be…”
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Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization
Published in PLoS genetics (01-05-2014)“…We have developed a new approach to characterize allele-specific timing of DNA replication genome-wide in human primary basophilic erythroblasts. We show that…”
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Production of embryonic and fetal-like red blood cells from human induced pluripotent stem cells
Published in PloS one (13-10-2011)“…We have previously shown that human embryonic stem cells can be differentiated into embryonic and fetal type of red blood cells that sequentially express three…”
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Predictable dynamic program of timing of DNA replication in human cells
Published in Genome research (01-12-2009)“…The organization of mammalian DNA replication is poorly understood. We have produced high-resolution dynamic maps of the timing of replication in human…”
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Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation
Published in Cell (29-12-2005)“…Linker histone H1 plays an important role in chromatin folding in vitro. To study the role of H1 in vivo, mouse embryonic stem cells null for three H1 genes…”
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Concise Review: Production of Cultured Red Blood Cells from Stem Cells
Published in Stem cells translational medicine (01-12-2012)“…The various cell sources, the niche applications most likely to reach the clinic first, and some of the remaining technical issues in the production of…”
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Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes
Published in Stem cell reports (14-07-2015)“…Hepatocyte transplantation has the potential to cure inherited liver diseases, but its application is impeded by a scarcity of donor livers. Therefore, we…”
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Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells
Published in Cell reports (Cambridge) (05-03-2019)“…Efficiency of reprogramming of human cells into induced pluripotent stem cells (iPSCs) has remained low. We report that individual adult human CD49f+ long-term…”
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Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1
Published in PloS one (08-06-2015)“…The molecular mechanisms governing γ-globin expression in a subset of fetal hemoglobin (α2γ2: HbF) expressing red blood cells (F-cells) and the mechanisms…”
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Distinct epigenetic features of differentiation-regulated replication origins
Published in Epigenetics & chromatin (10-05-2016)“…Eukaryotic genome duplication starts at discrete sequences (replication origins) that coordinate cell cycle progression, ensure genomic stability and modulate…”
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Gene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator
Published in PloS one (18-06-2009)“…Insertional mutagenesis has emerged as a major obstacle for gene therapy based on vectors that integrate randomly in the genome. Reducing the genotoxicity of…”
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Characterization of Hematopoiesis in Sickle Cell Disease by Prospective Isolation of Stem and Progenitor Cells
Published in Cells (Basel, Switzerland) (24-09-2020)“…The consequences of sickle cell disease (SCD) include ongoing hematopoietic stress, hemolysis, vascular damage, and effect of chronic therapies, such as blood…”
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Novel, High‐Yield Red Blood Cell Production Methods from CD34‐Positive Cells Derived from Human Embryonic Stem, Yolk Sac, Fetal Liver, Cord Blood, and Peripheral Blood
Published in Stem cells translational medicine (01-08-2012)“…The current supply of red blood cells expressing rare blood groups is not sufficient to cover all the existing transfusion needs for chronically transfused…”
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Complete genome phasing of family quartet by combination of genetic, physical and population-based phasing analysis
Published in PloS one (31-05-2013)“…Phased genome maps are important to understand genetic and epigenetic regulation and disease mechanisms, particularly parental imprinting defects. Phasing is…”
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