Search Results - "Bouez, Charbel"
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Utilization of ex vivo tissue model to study skin regeneration following microneedle stimuli
Published in Scientific reports (27-10-2022)“…Microneedling is a popular skin resurfacing and rejuvenation procedure. In order to develop better adjunct products for consumers, there is a scientific need…”
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2
The Development of Human Ex Vivo Models of Inflammatory Skin Conditions
Published in International journal of molecular sciences (08-12-2023)“…Traditional research in inflammatory dermatoses has relied on animal models and reconstructed human epidermis to study these conditions. However, these models…”
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3
A multi-study analysis enables identification of potential microbial features associated with skin aging signs
Published in Frontiers in aging (11-01-2024)“…During adulthood, the skin microbiota can be relatively stable if environmental conditions are also stable, yet physiological changes of the skin with age may…”
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4
Endocannabinoids Regulate Growth and Survival of Human Eccrine Sweat Gland–Derived Epithelial Cells
Published in Journal of investigative dermatology (01-08-2012)“…The functional existence of the emerging endocannabinoid system (ECS), one of the new neuroendocrine players in cutaneous biology, is recently described in the…”
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5
Activation of Toll-like receptors alters the microRNA expression profile of keratinocytes
Published in Experimental dermatology (01-04-2014)“…Keratinocytes recognize invading pathogens by various receptors, among them Toll‐like receptors (TLRs), and provide the first line of defense in skin immunity…”
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Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil
Published in Vigilância Sanitária em Debate (01-02-2018)“…Introduction: In 2014, Brazil has joined the growing list of countries to ban cosmetic products from being tested on animal models. The new legislation comes…”
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7
The Lysyl Oxidase LOX Is Absent in Basal and Squamous Cell Carcinomas and Its Knockdown Induces an Invading Phenotype in a Skin Equivalent Model
Published in Clinical cancer research (01-03-2006)“…Lysyl oxidase initiates the enzymatic stage of collagen and elastin cross-linking. Among five isoforms comprising the lysyl oxidase family, LOX is the better…”
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8
Optimization and characterization of an engineered human skin equivalent
Published in Tissue engineering (01-05-2005)“…Skin equivalents (SEs) have been designed to meet both basic and applied research needs. The successful application of tissue-engineered SEs requires that the…”
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9
Supplementation with a complex of active nutrients improved dermal and epidermal characteristics in skin equivalents generated from fibroblasts from young or aged donors
Published in Biogerontology (Dordrecht) (01-04-2007)“…Cultured skin equivalent (SE, Mimeskin) was generated by co-culturing skin fibroblasts and keratinocytes on a collagen-glycosaminoglycan-chitosan dermal…”
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Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals
Published in Journal of drugs in dermatology (01-07-2020)“…Visible light (400-700nm), which contributes to 45% of solar radiation, contributes to skin darkening and worsening of dyschromias, particularly in individuals…”
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SkinEthic™ RHE for in vitro evaluation of skin irritation of medical device extracts
Published in Toxicology in vitro (01-08-2018)“…According to ISO 10993 standards for biocompatibility of medical devices, skin irritation is one of the three toxicological endpoints to be always addressed in…”
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12
MiR-146a Negatively Regulates TLR2-Induced Inflammatory Responses in Keratinocytes
Published in Journal of investigative dermatology (01-07-2014)“…Keratinocytes represent the first line of defense against pathogens in the skin and have important roles in initiating and regulating inflammation during…”
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13
Alteration to the Skin Ceramide Profile Following Broad-Spectrum UV Exposure
Published in Journal of drugs in dermatology (01-01-2022)“…The epidermal stratum corneum (SC) lipid matrix, principally consisting of an equimolar ratio of ceramides, free fatty acids, and cholesterol, plays a crucial…”
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14
Oligomeric α-Synuclein induces skin degeneration in reconstructed human epidermis
Published in Neurobiology of aging (01-05-2022)“…•Reconstructed human epidermis (RHE) expresses α-Synuclein (α-Syn)•Oligomeric α-Synuclein (Oα-Syn) decreases proliferation in epidermal keratinocytes•Oα-Syn…”
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15
Long-Term Benefits of Daily Photo-Protection With a Broad-Spectrum Sunscreen in United States Hispanic Female Population
Published in Journal of drugs in dermatology (01-03-2020)“…aThe Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA bDepartment of Dermatology, Howard University, Washington, DC cL'Oreal…”
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16
The application of a multi‐component reaction peptide as a model regenerative active to enhance skin wound‐healing postlaser procedure in a double‐blinded placebo‐controlled clinical trial
Published in Journal of cosmetic dermatology (01-03-2024)“…Introduction Esthetic procedures are currently among the most effective options for consumers seeking to correct aging signs such as fine lines, wrinkles, and…”
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17
Activation of Toll‐like receptors alters the micro RNA expression profile of keratinocytes
Published in Experimental dermatology (01-04-2014)“…Abstract Keratinocytes recognize invading pathogens by various receptors, among them Toll‐like receptors ( TLR s), and provide the first line of defense in…”
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18
TGFβ signaling regulates lipogenesis in human sebaceous glands cells
Published in BMC dermatology (23-01-2013)“…Sebaceous glands are components of the skin essential for its normal lubrication by the production of sebum. This contributes to skin health and more…”
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Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil
Published in Vigilância Sanitária em Debate (01-02-2018)“…Introduction: In 2014, Brazil has joined the growing list of countries to ban cosmetic products from being tested on animal models. The new legislation comes…”
Get full text
Journal Article -
20
Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil
Published in Vigilância Sanitária em Debate (01-02-2018)“…Introduction: In 2014, Brazil has joined the growing list of countries to ban cosmetic products from being tested on animal models. The new legislation comes…”
Get full text
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