Search Results - "Bouderlique, T."

Autophagy and osteoarthritis development by Bouderlique, T, Vuppalapati, K.K, Newton, P.T, Li, L, Barenius, B, Ponzer, S, Chagin, A.S

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Cell Colonization Ability of a Commercialized Large Porous Alveolar Scaffold by Lemaire, Thibault, Chevallier, N., Courty, J., Rouard, H., Naili, S., Bouderlique, T., Lemonnier, S., Albanese, P.

“…The use of filling biomaterials or tissue-engineered large bone implant-coupling biocompatible materials and human bone marrow mesenchymal stromal cells seems…”
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Dynamic mesenchymal stem cells volumic seeding in a commercialized porous ceramic scaffold: a feasibility study by Lemonnier, S., Bouderlique, T., Albanese, P., Naili, S., Chevallier, N., Rouard, H., Courty, J., Lemaire, T.

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Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin by Kameneva, Polina, Artemov, Artem V., Kastriti, Maria Eleni, Faure, Louis, Olsen, Thale K., Otte, Jörg, Erickson, Alek, Semsch, Bettina, Andersson, Emma R., Ratz, Michael, Frisén, Jonas, Tischler, Arthur S., de Krijger, Ronald R., Bouderlique, Thibault, Akkuratova, Natalia, Vorontsova, Maria, Gusev, Oleg, Fried, Kaj, Sundström, Erik, Mei, Shenglin, Kogner, Per, Baryawno, Ninib, Kharchenko, Peter V., Adameyko, Igor

“…Characterization of the progression of cellular states during human embryogenesis can provide insights into the origin of pediatric diseases. We examined the…”
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Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis by Bouderlique, Thibault, Vuppalapati, Karuna K, Newton, Phillip T, Li, Lei, Barenius, Björn, Chagin, Andrei S

“…It has been suggested that the lysosomal recycling process called macro-autophagy plays a role in osteoarthritis development. We thus decided to genetically…”
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Rapid Isolation of Single Cells from Mouse and Human Teeth by Krivanek, Jan, Lavicky, Josef, Bouderlique, Thibault, Adameyko, Igor

“…Mouse and human teeth represent challenging organs for quick and efficient cell isolation for single-cell transcriptomic or other applications. The dental pulp…”
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Surface flow for colonial integration in reef-building corals by Bouderlique, Thibault, Petersen, Julian, Faure, Louis, Abed-Navandi, Daniel, Bouchnita, Anass, Mueller, Benjamin, Nazarov, Murtazo, Englmaier, Lukas, Tesarova, Marketa, Frade, Pedro R., Zikmund, Tomas, Koehne, Till, Kaiser, Jozef, Fried, Kaj, Wild, Christian, Pantos, Olga, Hellander, Andreas, Bythell, John, Adameyko, Igor

“…Reef-building corals are endangered animals with a complex colonial organization. Physiological mechanisms connecting multiple polyps and integrating them into…”
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Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase‐Dependent Cell Death and Leads to Mild Growth Retardation by Vuppalapati, Karuna K, Bouderlique, Thibault, Newton, Phillip T, Kaminskyy, Vitaliy O, Wehtje, Henrik, Ohlsson, Claes, Zhivotovsky, Boris, Chagin, Andrei S

“…ABSTRACT Longitudinal bone growth takes place in epiphyseal growth plates located in the ends of long bones. The growth plate consists of chondrocytes…”
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Superficial cells are self‐renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice by Li, Lei, Newton, Phillip T., Bouderlique, Thibault, Sejnohova, Marie, Zikmund, Tomas, Kozhemyakina, Elena, Xie, Meng, Krivanek, Jan, Kaiser, Jozef, Qian, Hong, Dyachuk, Vyacheslav, Lassar, Andrew B., Warman, Matthew L., Barenius, Björn, Adameyko, Igor, Chagin, Andrei S.

“…ABSTRACT Articular cartilage has little regenerative capacity. Recently, genetic lineage tracing experiments have revealed chondrocyte progenitors at the…”
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Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option by Dolinska, Monika, Cai, Huan, Månsson, Alma, Shen, Jingyi, Xiao, Pingnan, Bouderlique, Thibault, Li, Xidan, Leonard, Elory, Chang, Marcus, Gao, Yuchen, Medina, Juan Pablo, Kondo, Makoto, Sandhow, Lakshmi, Johansson, Anne-Sofie, Deneberg, Stefan, Söderlund, Stina, Jädersten, Martin, Ungerstedt, Johanna, Tobiasson, Magnus, Östman, Arne, Mustjoki, Satu, Stenke, Leif, Le Blanc, Katarina, Hellström-Lindberg, Eva, Lehmann, Sören, Ekblom, Marja, Olsson-Strömberg, Ulla, Sigvardsson, Mikael, Qian, Hong

“…•CXCL14 is lost in BM stromal cells in patients with CML, and restoring CXCL14 suppresses CML LSC engraftment in vivo and survival in vitro.•CXCL14 treatment…”
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A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes by Elvarsdóttir, Edda María, Mortera-Blanco, Teresa, Dimitriou, Marios, Bouderlique, Thibault, Jansson, Monika, Hofman, Isabel Juliana F., Conte, Simona, Karimi, Mohsen, Sander, Birgitta, Douagi, Iyadh, Woll, Petter S., Hellström-Lindberg, Eva

“…Established cell culture systems have failed to accurately recapitulate key features of terminal erythroid maturation, hampering our ability to in vitro model…”
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Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner by Newton, Phillip T, Vuppalapati, Karuna K, Bouderlique, Thibault, Chagin, Andrei S

“…Mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) is a protein-signaling complex at the fulcrum of anabolic and catabolic processes,…”
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FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development by Luu, Thuy T., Søndergaard, Jonas Nørskov, Peña-Pérez, Lucía, Kharazi, Shabnam, Krstic, Aleksandra, Meinke, Stephan, Schmied, Laurent, Frengen, Nicolai, Heshmati, Yaser, Kierczak, Marcin, Bouderlique, Thibault, Wagner, Arnika Kathleen, Gustafsson, Charlotte, Chambers, Benedict J., Achour, Adnane, Kutter, Claudia, Höglund, Petter, Månsson, Robert, Kadri, Nadir

“…Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant transformation, yet our knowledge of the underlying mechanisms…”
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In BTK, phosphorylated Y223 in the SH3 domain mirrors catalytic activity, but does not in fl uence biological function by Estupinan, HY, Bouderlique, T, He, C, Berglof, A, Cappelleri, A, Frengen, N, Zain, R, Karlsson, MCI, Mansson, R, Smith, CIE

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FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors by Peña-Pérez, Lucía, Kharazi, Shabnam, Frengen, Nicolai, Krstic, Aleksandra, Bouderlique, Thibault, Hauenstein, Julia, He, Minghui, Somuncular, Ece, Li Wang, Xiaoze, Dahlberg, Carin, Gustafsson, Charlotte, Johansson, Ann-Sofie, Walfridsson, Julian, Kadri, Nadir, Woll, Petter, Kierczak, Marcin, Qian, Hong, Westerberg, Lisa, Luc, Sidinh, Månsson, Robert

“…The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell…”
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Laminin α4 Deficiency Results in Impaired Hematopoietic Recovery Accompanied with Altered Bone Marrow Niche after Myelosuppression by Kondo, Makoto, Xiao, Pingnan, Sandhow, Lakshmi, Dolinska, Monika, Bouderlique, Thibault, Johansson, Anne-Sofie, Qian, Hong

“…Myelosuppression is a life-threatening complication of anti-cancer therapy including irradiation. Rapid and complete hematopoietic recovery after…”
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In BTK, phosphorylated Y223 in the SH3 domain mirrors catalytic activity, but does not influence biological function by Estupiñán, H. Yesid, Bouderlique, Thibault, He, Chenfei, Berglöf, Anna, Cappelleri, Andrea, Frengen, Nicolai, Zain, Rula, Karlsson, Mikael C. I., Månsson, Robert, Smith, C. I. Edvard

“…•In publications on BTK and its inhibitors, phosphorylation of tyrosine 223 is often considered necessary for complete catalytic activity.•We gene-edited mice…”
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The Concerted Action of E2-2 and HEB Is Critical for Early Lymphoid Specification by Bouderlique, Thibault, Peña-Pérez, Lucia, Kharazi, Shabnam, Hils, Miriam, Li, Xiaoze, Krstic, Aleksandra, De Paepe, Ayla, Schachtrup, Christian, Gustafsson, Charlotte, Holmberg, Dan, Schachtrup, Kristina, Månsson, Robert

“…The apparition of adaptive immunity in correlates with the expansion of the E-protein family to encompass E2-2, HEB, and E2A. Within the family, E2-2 and HEB…”
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Mesenchymal Stromal Cells, Instigator or Suppressor for the Development of MLL-AF9 Induced Acute Myeloid Leukemia? by Xiao, Pingnan, Heshmati, Yaser, Bouderlique, Thibault, Kondo, Makoto, Dolinska, Monika, Sandhow, Lakshmi, Johansson, Anne-Sofie, Walfridsson, Julian, Qian, Hong

“…It has been reported that bone marrow (BM) hematopoietic niche is critical for the maintenance of normal hematopoiesis and the development of hematopoietic…”
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Functional and Molecular Alterations of Bone Marrow Mesenchymal Stem and Progenitor Cells in Patients with Myelodysplastic Syndrome with Ring Sideroblast by Dolinska, Monika, Xiao, Pingnan, Johansson, Anne-Sofie, Sandhow, Lakshmi, Kondo, Makoto, Bouderlique, Thibault, Ungerstedt, Johanna, Hellstrom-Lindberg, Eva, Qian, Hong

“…Myelodysplastic Syndrome with Ring Sideroblast (MDS-RS), a clonal hematopoietic cell neoplasm, is low risk MDS, characterized by anemia, hyperplastic…”
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