Search Results - "Boucher, Wayne"
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3D structures of individual mammalian genomes studied by single-cell Hi-C
Published in Nature (London) (06-04-2017)“…The folding of genomic DNA from the beads-on-a-string-like structure of nucleosomes into higher-order assemblies is crucially linked to nuclear processes. Here…”
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The CCPN data model for NMR spectroscopy: Development of a software pipeline
Published in Proteins, structure, function, and bioinformatics (01-06-2005)“…To address data management and data exchange problems in the nuclear magnetic resonance (NMR) community, the Collaborative Computing Project for the NMR…”
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High-Resolution Heteronuclear Multidimensional NMR of Proteins in Living Insect Cells Using a Baculovirus Protein Expression System
Published in Journal of the American Chemical Society (06-02-2013)“…Recent developments in in-cell NMR techniques have allowed us to study proteins in detail inside living eukaryotic cells. In order to complement the existing…”
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FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells
Published in Nature communications (28-06-2018)“…A major challenge in single-molecule imaging is tracking the dynamics of proteins or complexes for long periods of time in the dense environments found in…”
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Citrullination of HP1γ chromodomain affects association with chromatin
Published in Epigenetics & chromatin (02-04-2019)“…Stem cell differentiation involves major chromatin reorganisation, heterochromatin formation and genomic relocalisation of structural proteins, including…”
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The CCPN Metabolomics Project: a fast protocol for metabolite identification by 2D-NMR
Published in Bioinformatics (15-03-2011)“…We present here the freely available Metabolomics Project resource specifically designed to work under the CcpNmr Analysis program produced by CCPN…”
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Treatment of Mental or Physical Health Problems in a Combat Zone: Comparisons of Postdeployment Mental Health and Early Separation From Service
Published in Journal of traumatic stress (01-04-2016)“…The primary aim of this study was to evaluate whether being treated for mental health or nonbattle physical injury during military combat deployment was…”
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Psychiatric diagnoses and treatment of U.S. military personnel while deployed to Iraq
Published in Military medicine (01-04-2012)“…Military personnel deployed in support of combat operations are at significantly higher risk for mental health problems. However, much of what we know about…”
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The CCPN project: an interim report on a data model for the NMR community
Published in Nature structural biology (01-06-2002)“…A recent workshop discusses the progress toward integrating NMR data into a unifying data model…”
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Theater Mental Health Encounter Data (TMHED): overview of study design and methods
Published in Military medicine (01-11-2011)“…Research has documented higher risks for mental health problems among service members deployed to war zones, yet a research limitation has been that assessment…”
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MEMOPS: Data modelling and automatic code generation
Published in Journal of integrative bioinformatics (01-12-2010)“…In recent years the amount of biological data has exploded to the point where much useful information can only be extracted by complex computational analyses…”
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CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis
Published in Journal of biomolecular NMR (01-10-2016)“…NMR spectroscopy is an indispensably powerful technique for the analysis of biomolecules under ambient conditions, both for structural- and functional studies…”
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Structure calculation, refinement and validation using CcpNmr Analysis
Published in Acta crystallographica. Section D, Biological crystallography. (01-01-2015)“…CcpNmr Analysis provides a streamlined pipeline for both NMR chemical shift assignment and structure determination of biological macromolecules. In addition,…”
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A software framework for analysing solid-state MAS NMR data
Published in Journal of biomolecular NMR (01-12-2011)“…Solid-state magic-angle-spinning (MAS) NMR of proteins has undergone many rapid methodological developments in recent years, enabling detailed studies of…”
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Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell
Published in Nature protocols (01-05-2018)“…This protocol shows how to combine fluorescence imaging with single-cell Hi-C, to study genome architecture in single cells with high resolution. Fluorescence…”
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Citrullination of HP1[gamma] chromodomain affects association with chromatin
Published in Epigenetics & chromatin (02-04-2019)“…Stem cell differentiation involves major chromatin reorganisation, heterochromatin formation and genomic relocalisation of structural proteins, including…”
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3D structure of individual mammalian genomes studied by single cell Hi-C
Published in Nature (London) (13-03-2017)“…The folding of genomic DNA from the beads-on-a-string like structure of nucleosomes into higher order assemblies is critically linked to nuclear processes. We…”
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Erratum to: CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis
Published in Journal of biomolecular NMR (01-04-2017)Get full text
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nomenclature and data model to describe NMR experiments
Published in Journal of biomolecular NMR (01-11-2006)“…Despite ongoing efforts in organising NMR information, there is no consistent and well-described generic standard for naming NMR experiments. The main reason…”
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A framework for scientific data modeling and automated software development
Published in Bioinformatics (15-04-2005)“…Motivation: The lack of standards for storage and exchange of data is a serious hindrance for the large-scale data deposition, data mining and program…”
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