Search Results - "Bouchard, D. J."

Infiltration of impacting droplets into porous substrates by Bouchard, D. J., Chandra, S.

“…The impact of water droplets on thin porous layers of glass beads held vertically between glass plates was photographed to observe simultaneous spreading and…”
Get full text

On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells by Gehrke, Iris, Bouchard, Eric D J, Beiggi, Sara, Poeppl, Armando G, Johnston, James B, Gibson, Spencer B, Banerji, Versha

“…Chronic lymphocytic leukemia (CLL) remains incurable despite advances in therapy. In this study, we characterize the effect of nicotinamide…”
Get full text

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells by Mutz, Cornelia N, Schwentner, Raphaela, Aryee, Dave N T, Bouchard, Eric D J, Mejia, Edgard M, Hatch, Grant M, Kauer, Maximilian O, Katschnig, Anna M, Ban, Jozef, Garten, Antje, Alonso, Javier, Banerji, Versha, Kovar, Heinrich

“…Ewing sarcoma (EwS) is the second most common bone cancer in children and adolescents with a high metastatic potential. EwS development is driven by a specific…”
Get full text

Mitochondrial Respiration Correlates with Prognostic Markers in Chronic Lymphocytic Leukemia and Is Normalized by Ibrutinib Treatment by Roy Chowdhury, Subir, Bouchard, Eric D J, Saleh, Ryan, Nugent, Zoann, Peltier, Cheryl, Mejia, Edgard, Hou, Sen, McFall, Carly, Squires, Mandy, Hewitt, Donna, Davidson, Linda, Shen, Garry X, Johnston, James B, Doucette, Christine, Hatch, Grant M, Fernyhough, Paul, Marshall, Aaron, Gibson, Spencer B, Dawe, David E, Banerji, Versha

“…Mitochondrial bioenergetics profiling, a measure of oxygen consumption rates, correlates with prognostic markers and can be used to assess response to therapy…”
Get full text

Homologous Recombination between a Lactococcal Bacteriophage and the Chromosome of Its Host Strain by Bouchard, Julie D., Moineau, Sylvain

“…Genetic exchanges constitute a significant means by which bacteriophages acquire novel characteristics. Phages of Lactococcus lactis occupy a particular niche,…”
Get full text

Lactococcal Phage Genes Involved in Sensitivity to AbiK and Their Relation to Single-Strand Annealing Proteins by BOUCHARD, Julie D, MOINEAU, Sylvain

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Transcriptional Modulation by Idelalisib Synergizes with Bendamustine in Chronic Lymphocytic Leukemia by Kost, Sara E. F., Saleh, Ali, Mejia, Edgard M., Mostafizar, Marina, Bouchard, Eric D. J., Banerji, Versha, Marshall, Aaron J., Gibson, Spencer B., Johnston, James B., Katyal, Sachin

“…The phosphatidyl-inositol 3 kinase (PI3K) δ inhibitor, idelalisib (IDE), is a potent inhibitor of the B-cell receptor pathway and a novel and highly effective…”
Get full text

Cross-resistance and synergy with bendamustine in chronic lymphocytic leukemia by Kost, Sara E.F, Bouchard, Eric D.J, LaBossière, Élise, Ye, Xibiao, Queau, Michelle L, Liang, William S, Banerji, Versha, Gibson, Spencer B, Katyal, Sachin, Johnston, James B

“…Highlights • Cross-resistance is observed between BEN, CLB and FLU in CLL cells. • Some BEN-resistant cells may respond to dADO/PEN. • CLL cells with a del 17p…”
Get full text

Characterization of the Two-Component Abortive Phage Infection Mechanism AbiT from Lactococcus lactis by Bouchard, Julie D, Dion, Eric, Bissonnette, Frédéric, Moineau, Sylvain

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Abstract 1891: Cross-resistance and synergy between idelalisib and bendamustine in chronic lymphocytic leukemia by Kost, Sara E. F., Saleh, Ali, Mejia, Edgard M., Mostafizar, Marina, Bouchard, Eric D. J., Banerji, Versha, Marshall, Aaron J., Gibson, Spencer B., Katyal, Sachin, Johnston, James B.

“…Abstract Idelalisib (IDE) is an inhibitor of the δ isoform of PI3 kinase and has shown high activity in chronic lymphocytic leukemia (CLL) either when given…”
Get full text

Effect of Si, Cu and Fe on mechanical properties of cast semi-solid 206 alloys by LEMIEUX, A., LANGLAIS, J., BOUCHARD, D., GRANT CHEN, X.

“…The development of a modified 206 alloy whose composition was optimized to minimize hot tearing during semi-solid forming was reported. The effect of varying…”
Get full text

Expression and Site-Directed Mutagenesis of the Lactococcal Abortive Phage Infection Protein AbiK by FORTIER, Louis-Charles, BOUCHARD, Julie D, MOINEAU, Sylvain

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Maxillofacial surgery and the dental auxiliary by Carlotti, A E, Bouchard, D J, Wolcott, D

Get more information

Abstract 3052: NAMPT inhibition induces mitochondrial dysfunction leading to apoptosis in chronic lymphocytic leukemia cells by Bouchard, Eric DJ, Mejia, Edgard M., Gehrke, Iris, Poeppl, Armando G., Hewitt, Donna, Johnston, James B., Gibson, Spencer B., Hatch, Grant M., Banerji, Versha

“…Abstract We have previously shown that the NAD depletion following inhibition of NAMPT by the NA-mimetic FK866 leads to loss of mitochondrial membrane…”
Get full text

Abstract 281: Bendamustine has the biochemical properties of an alkylating agent that synergizes with nucleoside analogues in chronic lymphocytic leukemia by Kost, Sara EF, Bouchard, Eric DJ, LaBossière, Élise, Ye, Xibiao, Queau, Michelle L., Liang, William S., Banerji, Versha, Gibson, Spencer B., Katyal, Sachin, Johnston, James B.

“…Abstract Bendamustine (BEN) is a promising new treatment for chronic lymphocytic leukemia (CLL) and may function as an alkylating agent (eg, chlorambucil, CLB)…”
Get full text

Seasonal variation of the beach profile at Miscou Island, New Brunswick: Effect of ice by Bouchard, J-D, Hill, P

“…Most previous studies on beach dynamics have been carried out in low-latitude regions or in summer, when the effect of ice is negligible. The objective of this…”
Get full text