Search Results - "Bouamar, R."

A Randomized Controlled Trial Comparing the Efficacy of Cyp3a5 Genotype‐Based With Body‐Weight‐Based Tacrolimus Dosing After Living Donor Kidney Transplantation by Shuker, N., Bouamar, R., Schaik, R. H. N., Clahsen‐van Groningen, M. C., Damman, J., Baan, C. C., Wetering, J., Rowshani, A. T., Weimar, W., Gelder, T., Hesselink, D. A.

“…Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with nonexpressers. This…”
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Tacrolimus Predose Concentrations Do Not Predict the Risk of Acute Rejection After Renal Transplantation: A Pooled Analysis From Three Randomized‐Controlled Clinical Trials by Bouamar, R., Shuker, N., Hesselink, D. A., Weimar, W., Ekberg, H., Kaplan, B., Bernasconi, C., Gelder, T.

“…Therapeutic drug monitoring (TDM) for tacrolimus (Tac) is universally applied. However, the concentration–effect relationship for Tac is poorly defined. This…”
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Follicular T helper cells and humoral reactivity in kidney transplant patients by de Graav, G. N., Dieterich, M., Hesselink, D. A., Boer, K., Clahsen‐van Groningen, M. C., Kraaijeveld, R., Litjens, N. H. R., Bouamar, R., Vanderlocht, J., Tilanus, M., Houba, I., Boonstra, A., Roelen, D. L., Claas, F. H. J., Betjes, M. G. H., Weimar, W., Baan, C. C.

“…Summary Memory B cells play a pivotal role in alloreactivity in kidney transplantation. Follicular T helper (Tfh) cells play an important role in the…”
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Conversion from tacrolimus to everolimus with complete and early glucocorticoid withdrawal after kidney transplantation: a randomised trial by Bouamar, R, Shuker, N, Osinga, J A J, Clahsen-van Groningen, M C, Damman, J, Baan, C C, van de Wetering, J, Rowshani, A T, Kal-van Gestel, J, Weimar, W, van Gelder, T, Hesselink, D A

“…While conversion from cyclosporine to everolimus is well documented, conversion from tacrolimus has been poorly studied. In this randomised, controlled trial…”
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The Optimal MMF Dose in Tacrolimus Treated Patients by van Gelder, T., Bouamar, R., Shuker, N., Hesselink, D., Weimar, W., Kaplan, B., Bernasconi, C.

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High intra-patient variability in tacrolimus clearance does not predict progression of cardiac allograft vasculopathy after heart transplantation by Bouamar, R, Shuker, N, Hesselink, D.A, Van Gelder, T, Caliskan, K, Manintveld, O.C, Balk, A.H.M.M, Constantinescu, A.A

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The Pharmacogenetics of Calcineurin Inhibitor-Related Nephrotoxicity by HESSELINK, Dennis A, BOUAMAR, Rachida, VAN GELDER, Teun

“…Chronic calcineurin inhibitor (CNI)-induced nephrotoxicity is associated with prolonged use of cyclosporine and tacrolimus and has been observed after all…”
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Genetic Polymorphisms in ABCB1 Influence the Pharmacodynamic Effects of Tacrolimus on T Cells: 1511 by Vafadari, R., Bouamar, R., Hesselink, D. A., van Schaik, R. H.N., Kraaijeveld, R., Weimar, W., Baan, C. C., van Gelder, T.

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Polymorphisms of the glucocorticoid receptor and avascular necrosis of the femoral heads after treatment with corticosteroids by Bouamar, Rachida, Koper, Jan Willem, van Rossum, Elisabeth F C, Weimar, Willem, van Gelder, Teun

“…A female patient developed avascular necrosis of the femoral heads after receiving low doses of glucocorticosteroids (GC) for 3 months. Genotyping of the GC…”
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