Search Results - "Boušová, Iva"

In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity by Šadibolová, Michaela, Juvonen, Risto O., Auriola, Seppo, Boušová, Iva

“…Sesquiterpene lactone helenalin is used as an antiphlogistic in European and Chinese folk medicine. The pharmacological activities of helenalin have been…”
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Antioxidant, pro-oxidant and other biological activities of sesquiterpenes by Bartikova, Hana, Hanusova, Veronika, Skalova, Lenka, Ambroz, Martin, Bousova, Iva

“…Sesquiterpenes, 15-carbon compounds formed from 3 isoprenoid units, are secondary metabolites produced mainly in higher plants but also in fungi and…”
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Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells by Ambrož, Martin, Lněničková, Kateřina, Matoušková, Petra, Skálová, Lenka, Boušová, Iva

“…Beer, the most popular beverage containing hops, is also frequently consumed by cancer patients. Moreover, non-alcoholic beer, owing to its nutritional value…”
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Sulforaphane Alters β-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes by Lněničková, Kateřina, Dymáková, Andrea, Szotáková, Barbora, Boušová, Iva

“…Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, exerts many beneficial effects on human health such as antioxidant, anti-inflammatory,…”
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The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells by Ambrož, Martin, Boušová, Iva, Skarka, Adam, Hanušová, Veronika, Králová, Věra, Matoušková, Petra, Szotáková, Barbora, Skálová, Lenka

“…The sesquiterpenes β-caryophyllene, β-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER), and valencene (VAL) are substantial components of the…”
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The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids by Lněničková, Kateřina, Šadibolová, Michaela, Matoušková, Petra, Szotáková, Barbora, Skálová, Lenka, Boušová, Iva

“…Prenylflavonoids in the human organism exhibit various health-beneficial activities, although they may interfere with drugs via the modulation of the…”
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MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis by Hanousková, Barbora, Vávrová, Gabriela, Ambrož, Martin, Boušová, Iva, Karlsen, Tommy A., Skálová, Lenka, Matoušková, Petra

“…Glutathione peroxidase 7 (GPx7) acts as an intracellular stress sensor/transmitter and plays an important role in adipocyte differentiation and the prevention…”
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The modulation of carbonyl reductase 1 by polyphenols by Boušová, Iva, Skálová, Lenka, Souček, Pavel, Matoušková, Petra

“…Carbonyl reductase 1 (CBR1), an enzyme belonging to the short-chain dehydrogenases/reductases family, has been detected in all human tissues. CBR1 catalyzes…”
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Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney by Kurtzeborn, Kristen, Kwon, Hyuk Nam, Iaroshenko, Vladislav, Faisal, Imrul, Ambrož, Martin, Jin, Xing, Qureshi, Talha, Kupari, Jussi, Ihermann-Hella, Anneliis, Väänänen, Juho, Tyynismaa, Henna, Boušová, Iva, Park, Sunghyouk, Kuure, Satu

“…MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling intracellular responses to growth factors and mechanical cues. The critical…”
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Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen by Zárybnický, Tomáš, Matoušková, Petra, Lancošová, Bibiána, Šubrt, Zdeněk, Skálová, Lenka, Boušová, Iva

“…Monoterpenes R-pulegone (PUL) and R-menthofuran (MF), abundant in the family, are frequently used in herb and food products. Although their hepatotoxicity was…”
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Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver by Šadibolová, Michaela, Zárybnický, Tomáš, Smutný, Tomáš, Pávek, Petr, Šubrt, Zdeněk, Matoušková, Petra, Skálová, Lenka, Boušová, Iva

“…Sesquiterpenes, the main components of plant essential oils, are bioactive compounds with numerous health-beneficial activities. Sesquiterpenes can interact…”
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The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR by Zárybnický, Tomáš, Matoušková, Petra, Ambrož, Martin, Šubrt, Zdeněk, Skálová, Lenka, Boušová, Iva

“…The selection of a suitable combination of reference genes (RGs) for data normalization is a crucial step for obtaining reliable and reproducible results from…”
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Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells by Ambrož, Martin, Hanušová, Veronika, Skarka, Adam, Boušová, Iva, Králová, Věra, Langhasová, Lenka, Skálová, Lenka

“…Essential oil from the leaves of Myrica rubra, a subtropical Asian fruit tree traditionally used in folk medicines, has a significant antiproliferative effect…”
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Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine by Bartíkova, Hana, Bousova, Iva, Jedlickova, Pavla, Lnenickova, Katerina, Skalova, Lenka, Szotakova, Barbora

“…The use of dietary supplements containing cranberry extract is a common way to prevent urinary tract infections. As consumption of these supplements containing…”
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Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro by Rudolfova, Petra, Hanusova, Veronika, Skalova, Lenka, Bartikova, Hana, Matouskova, Petra, Bousova, Iva

“…Catechins may influence both desirable and undesirable effects of many drugs. In this study, the in vitro effect of (+)-catechin, (-)-epicatechin,…”
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Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice by Bártíková, Hana, Boušová, Iva, Matoušková, Petra, Szotáková, Barbora, Skálová, Lenka

“…Green tea and green tea extracts (GTE) are often incorporated into diet intended to weight reduction, although the information about their efficacy in obese…”
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Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice by Boušová, Iva, Bártíková, Hana, Matoušková, Petra, Lněničková, Kateřina, Zappe, Lukáš, Valentová, Kateřina, Szotáková, Barbora, Martin, Jan, Skálová, Lenka

“…Abstract Consumption of antioxidant-enriched diets is 1 method of addressing obesity, which is associated with chronic oxidative stress and changes in the…”
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Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo by Matoušková, Petra, Bártíková, Hana, Boušová, Iva, Szotáková, Barbora, Martin, Jan, Skorkovská, Jana, Hanušová, Veronika, Tománková, Veronika, Anzenbacherová, Eva, Lišková, Barbora, Anzenbacher, Pavel, Skálová, Lenka

“…•Chronic consumption of green tea catechins in low doses seems to be safe.•Overdose consumption of catechins modulates several drug-metabolizing…”
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Hepatotoxicity of monoterpenes and sesquiterpenes by Zárybnický, Tomáš, Boušová, Iva, Ambrož, Martin, Skálová, Lenka

“…Public interest in natural therapies has increased significantly over past decades. Herbs and herbal products are extensively consumed worldwide and they are…”
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Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review by Svobodová, Gabriela, Horní, Martin, Velecká, Eva, Boušová, Iva

“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous condition characterized by liver steatosis, inflammation, consequent…”
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