Search Results - "Botto, M."

Intrinsic and extrinsic regulation of human skin melanogenesis and pigmentation by Serre, C., Busuttil, V., Botto, J.‐M.

“…In human skin, melanogenesis is a tightly regulated process. Indeed, several extracellular signals are transduced via dedicated signalling pathways and mostly…”
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Multipotentiality of skin‐derived precursors: application to the regeneration of skin and other tissues by Bergeron, L., Busuttil, V., Botto, J.‐M.

“…Skin‐derived precursors (SKPs) have been described as multipotent dermal precursors. Here, we provide a review of the breadth and depth of scientific…”
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Prevention of C5 Activation Ameliorates Spontaneous and Experimental Glomerulonephritis in Factor H-Deficient Mice by Pickering, M. C., Warren, J., Rose, K. L., Carlucci, F., Wang, Y., Walport, M. J., Cook, H. T., Botto, M.

“…Membranoproliferative glomerulonephritis (MPGN) type II (dense deposit disease) is an inflammatory renal disease characterized by electron-dense deposits and…”
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A triglyceride‐rich lipoprotein environment exacerbates renal injury in the accelerated nephrotoxic nephritis model by Saja, M. F., Cook, H. T., Ruseva, M. M., Szajna, M., Pickering, M. C., Woollard, K. J., Botto, M.

“…Summary Hyperlipidaemia accompanies chronic renal disease either as a consequence of the renal dysfunction or as part of generalized metabolic derangements…”
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The role of complement in the development of systemic lupus erythematosus by Manderson, Anthony P, Botto, Marina, Walport, Mark J

“…Complement has both beneficial and deleterious roles in the pathogenesis of systemic lupus erythematosus (SLE). On the one hand, patients with SLE present with…”
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CRM1 and chromosomal passenger complex component survivin are essential to normal mitosis progress and to preserve keratinocytes from mitotic abnormalities by Labarrade, F., Botto, J.-M., Domloge, N.

“…Objective Human epidermis provides the body a barrier against environmental assaults. To assume this function, the epidermis needs the renewal of keratinocytes…”
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Les phytoadaptogènes : une catégorie à part d’extraits de plantes aux propriétés pléiotropes d’adaptation à notre environnement by Botto, J.-M.

“…La consommation de parties définies de certaines plantes, sous forme de poudre sèche ou d’extrait, peut engendrer des bénéfices en matière de résistance et…”
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The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post‐transcriptional regulation of the IFN‐γ/CXCL10 IP‐10 pathway by Ambrose, N., Khan, E., Ravindran, R., Lightstone, L., Abraham, S., Botto, M., Johns, M., Haskard, D. O.

“…Summary The mechanisms underlying the exaggerated inflammatory response in Behçet's syndrome (BS) remain poorly understood. We investigated the response of…”
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Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells by Tas, S W, Quartier, P, Botto, M, Fossati-Jimack, L

“…Background: It has been suggested that defective handling of apoptotic cells by macrophages plays a key role in the development of systemic lupus erythematosus…”
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Analysis of HLA-G expression in renal tissue in lupus nephritis: a pilot study by Foschi, V, Bortolotti, D, Doyle, A F, Stratigou, V, Stephens, L, Trivedi, P, Rinaldi, R, Padovan, M, Bortoluzzi, A, Lightstone, L, Cairns, T D, Botto, M, Cook, T H, Rizzo, R, Govoni, M, Pickering, M C

“…Background The study aimed to investigate whether HLA-G antigen is expressed in the kidneys of patients affected by lupus nephritis (LN) and whether its…”
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Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity by Pepys, M.B, Bickerstaff, M.C.M, Botto, M, Hutchinson, W.L, Herbert, J, Tennent, G.A, Bybee, A, Mitchell, D.A, Cook, H.T, Butler, P.J.G, Walport, M.J

“…Serum amyloid P component (SAP), a highly conserved plasma protein named for its universal presence in amyloid deposits, is the single normal circulating…”
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Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes by Lee, H M, Wysoczynski, M, Liu, R, Shin, D-M, Kucia, M, Botto, M, Ratajczak, J, Ratajczak, M Z

“…We reported that complement cascade (CC) becomes activated in bone marrow (BM) during mobilization of hematopoietic stem/progenitor cells (HSPCs) induced by…”
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Complement deficiencies in humans and animals: Links to autoimmunity by Lewis, M. J., Botto, M.

“…Complement is involved in the pathogenesis of systemic lupus erythematosus (SLE) in multiple ways and may act as both friend and foe. Inherited homozygous…”
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Application of age estimation methods based on teeth eruption: how easy is Olze method to use? by De Angelis, D., Gibelli, D., Merelli, V., Botto, M., Ventura, F., Cattaneo, C.

“…The development of new methods for age estimation has become with time an urgent issue because of the increasing immigration, in order to estimate accurately…”
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A four-point molecular handover during Okazaki maturation by Botto, Margherita M., Borsellini, Alessandro, Lamers, Meindert H.

“…DNA replication introduces thousands of RNA primers into the lagging strand that need to be removed for replication to be completed. In Escherichia coli when…”
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Complement alternative pathway genetic variation and Dengue infection in the Thai population by Kraivong, R., Vasanawathana, S., Limpitikul, W., Malasit, P., Tangthawornchaikul, N., Botto, M., Screaton, G. R., Mongkolsapaya, J., Pickering, M. C.

“…Summary Dengue disease is a mosquito‐borne infection caused by Dengue virus. Infection may be asymptomatic or variably manifest as mild Dengue fever (DF) to…”
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Endogenous retrovirus expression during fruitfly metamorphosis enhances adult viral immunity by Botto, Juan M., Faulkner, Geoffrey J.

“…The evolutionary benefits of ongoing endogenous retrovirus (ERV) mobility in animals are largely unknown. A new paradigm suggests activation of the ERV family…”
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Achieving transport modal split targets at intermodal freight hubs using a model predictive approach by Nabais, J.L., Negenborn, R.R., Carmona Benítez, R.B., Ayala Botto, M.

“…The increase of international freight commerce is creating pressure on the existing transport network. Cooperation between the different transport parties…”
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A new model of atypical haemolytic uraemic syndrome by Vernon, K.A., Malik, T., Botto, M., Pickering, M.C.

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Identification of chromosome intervals from 129 and C57BL 6 mouse strains linked to the development of systemic lupus erythematosus by Heidari, Y, Bygrave, A E, Rigby, R J, Rose, K L, Walport, M J, Cook, H T, Vyse, T J, Botto, M

“…Systemic lupus erythematosus is an autoimmune disease in which complex interactions between genes and environmental factors determine the disease phenotype. We…”
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