Search Results - "Bottini, Silvia"

Viruses and miRNAs: More Friends than Foes by Bruscella, Patrice, Bottini, Silvia, Baudesson, Camille, Pawlotsky, Jean-Michel, Feray, Cyrille, Trabucchi, Michele

“…There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the replication and propagation of viruses. Expression or targeting of…”
Get full text

Benchmarking feature selection and feature extraction methods to improve the performances of machine-learning algorithms for patient classification using metabolomics biomedical data by Labory, Justine, Njomgue-Fotso, Evariste, Bottini, Silvia

“…Classification tasks are an open challenge in the field of biomedicine. While several machine-learning techniques exist to accomplish this objective, several…”
Get full text

Recent computational developments on CLIP-seq data analysis and microRNA targeting implications by Bottini, Silvia, Pratella, David, Grandjean, Valerie, Repetto, Emanuela, Trabucchi, Michele

“…Abstract Cross-Linking Immunoprecipitation associated to high-throughput sequencing (CLIP-seq) is a technique used to identify RNA directly bound to…”
Get full text

Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq by Bottini, Silvia, Hamouda-Tekaya, Nedra, Mategot, Raphael, Zaragosi, Laure-Emmanuelle, Audebert, Stephane, Pisano, Sabrina, Grandjean, Valerie, Mauduit, Claire, Benahmed, Mohamed, Barbry, Pascal, Repetto, Emanuela, Trabucchi, Michele

“…There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative…”
Get full text

Editorial: AI and multi-omics for rare diseases: challenges, advances and perspectives, Volume III by Emmert-Streib, Frank, Bottini, Silvia, Franco, Leonardo

Get full text

Editorial: AI and multi-omics for rare diseases: Challenges, advances and perspectives, Volume II by Bottini, Silvia, Emmert-Streib, Frank, Franco, Leonardo

Get full text

A Survey of Autoencoder Algorithms to Pave the Diagnosis of Rare Diseases by Pratella, David, Ait-El-Mkadem Saadi, Samira, Bannwarth, Sylvie, Paquis-Fluckinger, Véronique, Bottini, Silvia

“…Rare diseases (RDs) concern a broad range of disorders and can result from various origins. For a long time, the scientific community was unaware of RDs…”
Get full text

Cardiac dyspnea risk zones in the South of France identified by geo-pollution trends study by Simões, Fanny, Bouveyron, Charles, Piga, Damien, Borel, Damien, Descombes, Stéphane, Paquis-Flucklinger, Véronique, Levraut, Jaques, Gibelin, Pierre, Bottini, Silvia

“…The incidence of cardiac dyspnea (CD) and the distribution of pollution in the south of France suggests that environmental pollution may have a role in disease…”
Get full text

Editorial: AI and Multi-Omics for Rare Diseases: Challenges, Advances and Perspectives by Bottini, Silvia, Emmert-Streib, Frank, Franco, Leonardo

Get full text

Analysis of the Regulated Transcriptome of Neisseria meningitidis in Human Blood Using a Tiling Array by Del Tordello, Elena, Bottini, Silvia, Muzzi, Alessandro, Serruto, Davide

“…Neisseria meningitidis is the major cause of septicemia and meningococcal meningitis. During the course of infection, the bacterium must adapt to different…”
Get full text

Multi-Omics Approaches to Improve Mitochondrial Disease Diagnosis: Challenges, Advances, and Perspectives by Labory, Justine, Fierville, Morgane, Ait-El-Mkadem, Samira, Bannwarth, Sylvie, Paquis-Flucklinger, Véronique, Bottini, Silvia

“…Mitochondrial diseases (MD) are rare disorders caused by deficiency of the mitochondrial respiratory chain, which provides energy in each cell. They are…”
Get full text

Global transcriptome analysis reveals small RNAs affecting Neisseria meningitidis bacteremia by Fagnocchi, Luca, Bottini, Silvia, Golfieri, Giacomo, Fantappiè, Laura, Ferlicca, Francesca, Antunes, Ana, Guadagnuolo, Serafina, Del Tordello, Elena, Siena, Emilio, Serruto, Davide, Scarlato, Vincenzo, Muzzi, Alessandro, Delany, Isabel

“…Most bacterial small RNAs (sRNAs) are post-transcriptional regulators involved in adaptive responses, controlling gene expression by modulating translation or…”
Get full text

GenomeMixer and TRUST: Novel bioinformatics tools to improve reliability of Non-Invasive Prenatal Testing (NIPT) for fetal aneuploidies by Pratella, David, Duboc, Véronique, Milanesio, Marco, Boudjarane, John, Descombes, Stéphane, Paquis-Flucklinger, Véronique, Bottini, Silvia

“…[Display omitted] Non-invasive prenatal testing (NIPT) screens for common fetal chromosomal abnormalities through analysis of circulating cell-free DNA in…”
Get full text

Identification and characterization of specific motifs in effector proteins of plant parasites using MOnSTER by Calia, Giulia, Porracciolo, Paola, Chen, Yongpan, Kozlowski, Djampa, Schuler, Hannes, Cestaro, Alessandro, Quentin, Michaël, Favery, Bruno, Danchin, Etienne G. J., Bottini, Silvia

“…Plant pathogens cause billions of dollars of crop loss every year and are a major threat to global food security. Identifying and characterizing pathogens…”
Get full text

Videothoracoscopic-guided management of a central vein perforation during hemodialysis catheter placement by Kuzniec, Sérgio, PhD, MD, Natal, Sílvia Regina Bottini, MD, Werebe, Eduardo de Campos, PhD, MD, Wolosker, Nelson, PhD, MD

“…We present a case of the successful repair of an iatrogenic central vein lesion using a videothoracoscopic approach. The confluence of the right innominate…”
Get full text

PIPE-chipSAD: A Pipeline for the Analysis of High Density Arrays of Bacterial Transcriptomes by Bottini, Silvia, Del Tordello, Elena, Fagnocchi, Luca, Donati, Claudio, Muzzi, Alessandro

“…is a pipeline for bacterial transcriptome studies based on high-density microarray experiments. The main algorithm , integrates the analysis of the…”
Get full text

RNY (YRNA)-derived small RNAs regulate cell death and inflammation in monocytes/macrophages by Hizir, Zoheir, Bottini, Silvia, Grandjean, Valerie, Trabucchi, Michele, Repetto, Emanuela

“…The recent discovery of new classes of small RNAs has opened unknown territories to explore new regulations of physiopathological events. We have recently…”
Get full text

From benchmarking HITS-CLIP peak detection programs to a new method for identification of miRNA-binding sites from Ago2-CLIP data by Bottini, Silvia, Hamouda-Tekaya, Nedra, Tanasa, Bogdan, Zaragosi, Laure-Emmanuelle, Grandjean, Valerie, Repetto, Emanuela, Trabucchi, Michele

“…Experimental evidence indicates that about 60% of miRNA-binding activity does not follow the canonical rule about the seed matching between miRNA and target…”
Get full text

Case report: leishmaniasis of the upper lip by Veraldi, Stefano, MD, Bottini, Silvia, MD, Persico, Maria Chiara, MD, Lunardon, Luisa, MD

“…We report a case of leishmaniasis localized to the upper lip in a 77-year-old Italian man. The disease was characterized by a severe swelling which involved…”
Get full text

Tropical ulcers: the first imported cases and review of the literature by Veraldi, Stefano, Faraci, Andrea G., Valentini, Davide, Bottini, Silvia

“…Background Atropical ulcer is a bacterial necrotizing disease of the skin, with an acute or chronic linical course, caused by anaerobic bacteria, notably…”
Get full text