Search Results - "Botti, Claudio"
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Outcome Evaluation after 2023 Nipple-Sparing Mastectomies: Our Experience
Published in Plastic and reconstructive surgery (1963) (01-02-2017)“…Although quadrantectomy and lumpectomy help diminish the psychological and physical devastation inflicted, mastectomy is still elected in 20 to 30 percent of…”
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Comparison of Indocyanine Green with conventional tracers for sentinel lymph node biopsy in breast cancer: A multidisciplinary evaluation of clinical effectiveness, safety, organizational and economic impact
Published in PloS one (29-08-2024)“…Breast cancer is a global health problem, and sentinel lymph node biopsy (SLNB) is the standard procedure for early-stage breast cancer. Technetium-99 (TC-99),…”
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Neoadjuvant Endocrine Therapy in Breast Cancer: Current Knowledge and Future Perspectives
Published in International journal of molecular sciences (16-05-2020)“…In locally advanced (LA) breast cancer (BC), neoadjuvant treatments have led to major achievements, which hold particular relevance in HER2-positive and…”
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A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions
Published in Molecular cancer (22-07-2022)“…Keywords: Breast cancer metastases, Organoids, Alpelisib, PIK3CA mutations…”
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Impact of BMI on HER2+ metastatic breast cancer patients treated with pertuzumab and/or trastuzumab emtansine. Real‐world evidence
Published in Journal of cellular physiology (01-11-2020)“…Body mass index (BMI) is a main indicator of obesity and its association with breast cancer is well established. However, little is known in the metastatic…”
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Stereotactic partial breast irradiation in primary breast cancer: A comprehensive review of the current status and future directions
Published in Frontiers in oncology (13-10-2022)“…In selected low-risk breast cancer patients, accelerated partial breast irradiation (APBI) may represent an alternative option to the whole breast irradiation…”
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Bcl-2 dependent modulation of Hippo pathway in cancer cells
Published in Cell communication and signaling (16-05-2024)“…Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in…”
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Reverse strategy to locally advanced breast implant-associated anaplastic large cell lymphoma: A case report
Published in Frontiers in oncology (10-01-2023)“…Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell lymphoma associated with textured breast implants. The most common…”
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How Dual-Energy Contrast-Enhanced Spectral Mammography Can Provide Useful Clinical Information About Prognostic Factors in Breast Cancer Patients: A Systematic Review of Literature
Published in Frontiers in oncology (22-07-2022)“…Introduction In the past decade, a new technique derived from full-field digital mammography has been developed, named contrast-enhanced spectral mammography…”
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Breast cancer surgery during the Covid-19 pandemic: a monocentre experience from the Regina Elena National Cancer Institute of Rome
Published in Journal of experimental & clinical cancer research (27-08-2020)“…The Covid-19 pandemic has challenged hard the national health systems worldwide. According to the national policy issued in March 2020 in response to the…”
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Breast and cervical cancer in transgender men: literature review and a case report
Published in Therapeutic advances in medical oncology (01-01-2024)“…Transgender individuals exhibit a higher prevalence of cancer-related risk factors, such as substance abuse and sexually transmitted infections. These factors,…”
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Observational study of coagulation activation in early breast cancer: development of a prognostic model based on data from the real world setting
Published in Journal of translational medicine (16-05-2018)“…Cancer and coagulation activation are tightly related. The extent to which factors related to both these pathologic conditions concur to patient prognosis…”
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Breast cancer metastasis: Is it a matter of OMICS and proper ex-vivo models?
Published in Computational and structural biotechnology journal (01-01-2022)“…Genomics has greatly increased the understanding of the study of breast cancer (BC) and has shaped the concept of intra-tumor heterogeneity, currently…”
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Quantitative molecular analysis of sentinel lymph node may be predictive of axillary node status in breast cancer classified by molecular subtypes
Published in PloS one (22-03-2013)“…To determine the performance of intraoperative one-step nucleic acid amplification (OSNA) assay in detecting sentinel lymph node metastases compared to…”
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Immnunohistochemical Expression and Prognostic Significance of Fatty Acid Synthase in Pancreatic Carcinoma
Published in Anticancer research (01-07-2007)“…Background: The aim of this study was to evaluate immunohistochemical markers in pancreatic cancer and to determine the association of their expression with…”
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The Cytoskeleton Regulatory Protein hMena (ENAH) Is Overexpressed in Human Benign Breast Lesions with High Risk of Transformation and Human Epidermal Growth Factor Receptor-2–Positive/Hormonal Receptor–Negative Tumors
Published in Clinical cancer research (01-03-2006)“…Purpose: hMena (ENAH), a cytoskeleton regulatory protein involved in the regulation of cell motility and adhesion, is overexpressed in breast cancer. The aim…”
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Impact of Five Prophylactic Filgrastim Schedules on Hematologic Toxicity in Early Breast Cancer Patients Treated With Epirubicin and Cyclophosphamide
Published in Journal of clinical oncology (01-10-2005)“…To evaluate the comparative efficacy of varying intensity schedules of recombinant human granulocyte colony-stimulating factor (G-CSF; filgrastim) support in…”
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Fatty Acid Synthase (FAS) is a Marker of Increased Risk of Recurrence in Lung Carcinoma
Published in Anticancer research (01-11-2004)“…Background: We explored the expression of Fatty Acid Synthase (FAS) in lung carcinomas and its association with clinico-pathological features and prognosis…”
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Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer
Published in Expert opinion on pharmacotherapy (01-04-2013)“…Lapatinib, a dual HER2/EGFR tyrosine kinase inhibitor (TKI), associated to capecitabine represents the treatment of choice in HER2-positive metastatic breast…”
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A multicenter prospective phase II randomized trial of epirubicin/vinorelbine versus pegylated liposomal doxorubicin/vinorelbine as first-line treatment in advanced breast cancer. A GOIM study
Published in Journal of experimental & clinical cancer research (12-04-2011)“…To evaluate activity and tolerability of two anthracycline-containing regimens as first-line treatment for anthracycline-naïve relapsed breast cancer patients…”
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