Search Results - "Botker, Johan"

Tailor‐Made Doses of Pharmaceuticals by Tunable Modular Design: A Case Study on Tapering Antidepressant Medication by Ahola, Ilari, Raijada, Dhara, Cornett, Claus, Bøtker, Johan, Rantanen, Jukka, Genina, Natalja

“…An abrupt cessation of antidepressant medication can be challenging due to the appearance of withdrawal symptoms. A slow hyperbolic tapering of an…”
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Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling by Aho, Johanna, Bøtker, Johan Peter, Genina, Natalja, Edinger, Magnus, Arnfast, Lærke, Rantanen, Jukka

“…Application of additive manufacturing techniques (3D printing) for mass-customized products has boomed in the recent years. In pharmaceutical industry and…”
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Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing by Öblom, Heidi, Cornett, Claus, Bøtker, Johan, Frokjaer, Sven, Hansen, Harald, Rades, Thomas, Rantanen, Jukka, Genina, Natalja

“…[Display omitted] Medical cannabis has shown to be effective in various diseases that have not successfully been treated with other marketed drug products…”
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In silico design and 3D printing of microfluidic chips for the preparation of size-controllable siRNA nanocomplexes by Li, Yongquan, Bøtker, Johan, Rantanen, Jukka, Yang, Mingshi, Bohr, Adam

“…[Display omitted] Small interfering RNA (siRNA) is regarded as one of the most powerful tools for the treatment of various diseases by downregulating the…”
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Near-infrared chemical imaging (NIR-CI) of 3D printed pharmaceuticals by Khorasani, Milad, Edinger, Magnus, Raijada, Dhara, Bøtker, Johan, Aho, Johanna, Rantanen, Jukka

“…[Display omitted] Hot-melt extrusion and 3D printing are enabling manufacturing approaches for patient-centred medicinal products. Hot-melt extrusion is a…”
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Assessment of subvisible particles in biopharmaceuticals with image feature extraction and machine learning by Maharjan, Ravi, Lee, Jae Chul, Bøtker, Johan Peter, Kim, Ki Hyun, Kim, Nam Ah, Jeong, Seong Hoon, Rantanen, Jukka

“…An image classification tool was developed to classify subvisible particles, namely silicone oil (SO) and non-silicone oil (NSO; protein aggregate, rubber…”
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Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance by Bock, Frederik, Bøtker, Johan Peter, Larsen, Susan Weng, Lu, Xujin, Østergaard, Jesper

“…A UV imaging release-testing setup comprising an agarose gel as a model for tumorous tissue was developed. The setup was optimized with respect to agarose…”
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Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation by Mortensen, Janni Støvring, Bohr, Søren S.-R., Krog, Lasse Skjoldborg, Bøtker, Johan Peter, Kapousidou, Vaya, Saaby, Lasse, Hatzakis, Nikos S., Mørck Nielsen, Hanne, Nguyen, Duc Ninh, Rønholt, Stine

“…The integrity of the intestinal mucus barrier is crucial for human health, as it serves as the body's first line of defense against pathogens. However,…”
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Medication Tracking: Design and Fabrication of a Dry Powder Inhaler with Integrated Acoustic Element by 3D Printing by Li, Yongquan, Bohr, Adam, Jensen, Henrik, Rantanen, Jukka, Cornett, Claus, Beck-Broichsitter, Moritz, Bøtker, Johan Peter

“…Purpose Asthma is a prevalent lung disorder that cause heavy burdens globally. Inhalation medicaments can relieve symptoms, improve lung function and, thus,…”
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Dehydration of Nitrofurantoin Monohydrate during Melt Extrusion by Raijada, Dhara, Arnfast, Lærke, Bond, Andrew D, Aho, Johanna, Bøtker, Johan, Sandler, Niklas, Rantanen, Jukka

“…Hot melt extrusion is important for the development of advanced pharmaceutical dosage forms. In this study, the dehydration of nitrofurantoin monohydrate…”
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Additive manufacturing of prototype elements with process interfaces for continuously operating manufacturing lines by Hirschberg, Cosima, Schmidt Larsen, Mikkel, Bøtker, Johan Peter, Rantanen, Jukka

“…Rapid prototyping based on in silico design and 3D printing enables fast customization of complex geometries to multiple needs. This study utilizes, additive…”
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Characterisation of pore structures of pharmaceutical tablets: A review by Markl, Daniel, Strobel, Alexa, Schlossnikl, Rüdiger, Bøtker, Johan, Bawuah, Prince, Ridgway, Cathy, Rantanen, Jukka, Rades, Thomas, Gane, Patrick, Peiponen, Kai-Erik, Zeitler, J. Axel

“…[Display omitted] Traditionally, the development of a new solid dosage form is formulation-driven and less focus is put on the design of a specific…”
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging by Markl, Daniel, Zeitler, J. Axel, Rasch, Cecilie, Michaelsen, Maria Høtoft, Müllertz, Anette, Rantanen, Jukka, Rades, Thomas, Bøtker, Johan

“…Purpose A 3D printer was used to realise compartmental dosage forms containing multiple active pharmaceutical ingredient (API) formulations. This work…”
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Co-administration of Intravenous Drugs: Rapidly Troubleshooting the Solid Form Composition of a Precipitate in a Multi-drug Mixture Using On-Site Raman Spectroscopy by Nilsson, Niklas, Nezvalova-Henriksen, Katerina, Bøtker, Johan P., Højmark Andersen, Niels, Strøm Larsen, Bjarke, Rantanen, Jukka, Tho, Ingunn, Brustugun, Jørgen

“…Intravenous drugs are often co-administrated in the same intravenous catheter line due to which compatibility issues, such as complex precipitation processes…”
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Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy by Ueda, Hiroshi, Peter Bøtker, Johan, Edinger, Magnus, Löbmann, Korbinian, Grohganz, Holger, Müllertz, Anette, Rades, Thomas, Østergaard, Jesper

“…[Display omitted] Co-amorphous systems comprising low-molecular weight drugs and co-formers constitute an interesting approach to optimize pharmaceutical…”
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Data-Enriched Edible Pharmaceuticals (DEEP) with Bespoke Design, Dose and Drug Release by Chao, Meie, Öblom, Heidi, Cornett, Claus, Bøtker, Johan, Rantanen, Jukka, Sporrong, Sofia Kälvemark, Genina, Natalja

“…Data-enriched edible pharmaceuticals (DEEP) is an approach to obtain personalized medicine, in terms of flexible and precise drug doses, while at the same time…”
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Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions by Bøtker, Johan P., Karmwar, Pranav, Strachan, Clare J., Cornett, Claus, Tian, Fang, Zujovic, Zoran, Rantanen, Jukka, Rades, Thomas

“…The aim of this study was to investigate the usefulness of the atomic pair-wise distribution function (PDF) to detect the extension of disorder/amorphousness…”
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Measurement of hydrogen peroxide vapor in powders with potassium titanium oxide oxalate loaded cellulose pellets as probes by Kastvig, Maria H., Bøtker, Johan P., Ge, Ge, Andersen, Mogens L.

“…An image-based method for determining H2O2 vapor pressures in powder systems was developed based on cellulose pellets loaded with potassium titanium oxide…”
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Physical Stability of Freeze-Dried Isomalt Diastereomer Mixtures by Koskinen, Anna-Kaisa, Fraser-Miller, Sara J., Bøtker, Johan P., Heljo, Ville P., Barnsley, Jonathan E., Gordon, Keith C., Strachan, Clare J., Juppo, Anne M.

“…ABSTRACT Purpose Isomalt is a sugar alcohol used as an excipient in commercially available solid oral dosage forms. The potential of isomalt as a novel…”
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Transforming nanomedicine manufacturing toward Quality by Design and microfluidics by Colombo, Stefano, Beck-Broichsitter, Moritz, Bøtker, Johan Peter, Malmsten, Martin, Rantanen, Jukka, Bohr, Adam

“…Nanopharmaceuticals aim at translating the unique features of nano-scale materials into therapeutic products and consequently their development relies…”
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