Search Results - "Bothner, Brian"

Refine Results
  1. 1

    Aerobic bacterial methane synthesis by Wang, Qian, Alowaifeer, Abdullah, Kerner, Patricia, Balasubramanian, Narayanaganesh, Patterson, Angela, Christian, William, Tarver, Angela, Dore, John E., Hatzenpichler, Roland, Bothner, Brian, McDermott, Timothy R.

    “…Reports of biogenic methane (CH₄) synthesis associated with a range of organisms have steadily accumulated in the literature. This has not happened without…”
    Get full text
    Journal Article
  2. 2

    New Technologies for Studying Biofilms by Franklin, Michael J, Chang, Connie, Akiyama, Tatsuya, Bothner, Brian

    Published in Microbiology spectrum (01-08-2015)
    “…Bacteria have traditionally been studied as single-cell organisms. In laboratory settings, aerobic bacteria are usually cultured in aerated flasks, where the…”
    Get more information
    Journal Article
  3. 3

    Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking by Venkatakrishnan, Balasubramanian, Yarbrough, Joseph, Domsic, John, Bennett, Antonette, Bothner, Brian, Kozyreva, Olga G., Samulski, R. Jude, Muzyczka, Nicholas, McKenna, Robert, Agbandje-McKenna, Mavis

    Published in Journal of Virology (01-05-2013)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
    Get full text
    Journal Article
  4. 4

    Hepatitis B Virus Core Protein Phosphorylation Sites Affect Capsid Stability and Transient Exposure of the C-terminal Domain by Selzer, Lisa, Kant, Ravi, Wang, Joseph C.-Y., Bothner, Brian, Zlotnick, Adam

    Published in The Journal of biological chemistry (20-11-2015)
    “…Hepatitis B virus core protein has 183 amino acids divided into an assembly domain and an arginine-rich C-terminal domain (CTD) that regulates essential…”
    Get full text
    Journal Article
  5. 5

    Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics by Rayaprolu, Vamseedhar, Kruse, Shannon, Kant, Ravi, Venkatakrishnan, Balasubramanian, Movahed, Navid, Brooke, Dewey, Lins, Bridget, Bennett, Antonette, Potter, Timothy, McKenna, Robert, Agbandje-McKenna, Mavis, Bothner, Brian

    Published in Journal of Virology (01-12-2013)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
    Get full text
    Journal Article
  6. 6

    Acute stress reduces population-level metabolic and proteomic variation by Steward, Katherine F, Refai, Mohammed, Dyer, William E, Copié, Valérie, Lachowiec, Jennifer, Bothner, Brian

    Published in BMC bioinformatics (07-03-2023)
    “…Variation in omics data due to intrinsic biological stochasticity is often viewed as a challenging and undesirable feature of complex systems analyses. In…”
    Get full text
    Journal Article
  7. 7

    An Aurora B-RPA signaling axis secures chromosome segregation fidelity by Roshan, Poonam, Kuppa, Sahiti, Mattice, Jenna R., Kaushik, Vikas, Chadda, Rahul, Pokhrel, Nilisha, Tumala, Brunda R., Biswas, Aparna, Bothner, Brian, Antony, Edwin, Origanti, Sofia

    Published in Nature communications (25-05-2023)
    “…Errors in chromosome segregation underlie genomic instability associated with cancers. Resolution of replication and recombination intermediates and protection…”
    Get full text
    Journal Article
  8. 8
  9. 9

    Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes by Deveryshetty, Jaigeeth, Chadda, Rahul, Mattice, Jenna R., Karunakaran, Simrithaa, Rau, Michael J., Basore, Katherine, Pokhrel, Nilisha, Englander, Noah, Fitzpatrick, James A. J., Bothner, Brian, Antony, Edwin

    Published in Nature communications (05-10-2023)
    “…Homologous recombination (HR) is an essential double-stranded DNA break repair pathway. In HR, Rad52 facilitates the formation of Rad51 nucleoprotein filaments…”
    Get full text
    Journal Article
  10. 10

    Rtt105 regulates RPA function by configurationally stapling the flexible domains by Kuppa, Sahiti, Deveryshetty, Jaigeeth, Chadda, Rahul, Mattice, Jenna R., Pokhrel, Nilisha, Kaushik, Vikas, Patterson, Angela, Dhingra, Nalini, Pangeni, Sushil, Sadauskas, Marisa K., Shiekh, Sajad, Balci, Hamza, Ha, Taekjip, Zhao, Xiaolan, Bothner, Brian, Antony, Edwin

    Published in Nature communications (02-09-2022)
    “…Replication Protein A (RPA) is a heterotrimeric complex that binds to single-stranded DNA (ssDNA) and recruits over three dozen RPA-interacting proteins to…”
    Get full text
    Journal Article
  11. 11

    Metalloproteomics Reveals Multi-Level Stress Response in Escherichia coli When Exposed to Arsenite by Larson, James, Sather, Brett, Wang, Lu, Westrum, Jade, Tokmina-Lukaszewska, Monika, Pauley, Jordan, Copié, Valérie, McDermott, Timothy R, Bothner, Brian

    “…The operon encodes a three-protein arsenic resistance system. ArsR regulates the transcription of the operon, while ArsB and ArsC are involved in exporting…”
    Get full text
    Journal Article
  12. 12
  13. 13

    Introducing the ArsR-Regulated Arsenic Stimulon by Rawle, Rachel, Saley, Tara C, Kang, Yoon-Suk, Wang, Qian, Walk, Seth, Bothner, Brian, McDermott, Timothy R

    Published in Frontiers in microbiology (03-03-2021)
    “…The microbial operon encodes the primary bacterial defense response to the environmental toxicant, arsenic. An important component of this operon is the gene,…”
    Get full text
    Journal Article
  14. 14

    Thermal Stability as a Determinant of AAV Serotype Identity by Bennett, Antonette, Patel, Saajan, Mietzsch, Mario, Jose, Ariana, Lins-Austin, Bridget, Yu, Jennifer C, Bothner, Brian, McKenna, Robert, Agbandje-McKenna, Mavis

    “…Currently, there are over 150 ongoing clinical trials utilizing adeno-associated viruses (AAVs) to target various genetic diseases, including hemophilia (AAV2…”
    Get full text
    Journal Article
  15. 15

    Arsenite oxidase also functions as an antimonite oxidase by Wang, Qian, Warelow, Thomas P, Kang, Yoon-Suk, Romano, Christine, Osborne, Thomas H, Lehr, Corinne R, Bothner, Brian, McDermott, Timothy R, Santini, Joanne M, Wang, Gejiao

    Published in Applied and Environmental Microbiology (01-03-2015)
    “…Arsenic and antimony are toxic metalloids and are considered priority environmental pollutants by the U.S. Environmental Protection Agency. Significant…”
    Get full text
    Journal Article
  16. 16

    Longitudinal analysis of the Five Sisters hot springs in Yellowstone National Park reveals a dynamic thermoalkaline environment by Peach, Jesse T., Mueller, Rebecca C., Skorupa, Dana J., Mesle, Margaux M., Kanta, Sutton, Boltinghouse, Eric, Sharon, Bailey, Copié, Valerie, Bothner, Brian, Peyton, Brent M.

    Published in Scientific reports (04-11-2022)
    “…Research focused on microbial populations of thermoalkaline springs has been driven in a large part by the lure of discovering functional enzymes with…”
    Get full text
    Journal Article
  17. 17

    Metabolic Implications of Using BioOrthogonal Non-Canonical Amino Acid Tagging (BONCAT) for Tracking Protein Synthesis by Steward, Katherine F, Eilers, Brian, Tripet, Brian, Fuchs, Amanda, Dorle, Michael, Rawle, Rachel, Soriano, Berliza, Balasubramanian, Narayanaganesh, Copié, Valérie, Bothner, Brian, Hatzenpichler, Roland

    Published in Frontiers in microbiology (13-02-2020)
    “…BioOrthogonal Non-Canonical Amino acid Tagging (BONCAT) is a powerful tool for tracking protein synthesis on the level of single cells within communities and…”
    Get full text
    Journal Article
  18. 18

    Regulatory Activities of Four ArsR Proteins in Agrobacterium tumefaciens 5A by Kang, Yoon-Suk, Brame, Keenan, Jetter, Jonathan, Bothner, Brian B, Wang, Gejiao, Thiyagarajan, Saravanamuthu, McDermott, Timothy R

    Published in Applied and environmental microbiology (15-06-2016)
    “…ArsR is a well-studied transcriptional repressor that regulates microbe-arsenic interactions. Most microorganisms have an arsR gene, but in cases where…”
    Get full text
    Journal Article
  19. 19

    Mechanical coupling in the nitrogenase complex by Huang, Qi, Tokmina-Lukaszewska, Monika, Johnson, Lewis E, Kallas, Hayden, Ginovska, Bojana, Peters, John W, Seefeldt, Lance C, Bothner, Brian, Raugei, Simone

    Published in PLoS computational biology (04-03-2021)
    “…The enzyme nitrogenase reduces dinitrogen to ammonia utilizing electrons, protons, and energy obtained from the hydrolysis of ATP. Mo-dependent nitrogenase is…”
    Get full text
    Journal Article
  20. 20