Search Results - "Bothe, U"

Protein kinases as small molecule inhibitor targets in inflammation by Gaestel, M, Mengel, A, Bothe, U, Asadullah, K

“…The human kinome describes a major group of intracellular signalling molecules. In the last few years, many molecules in the group have become targets for…”
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Novel Carboranyl C-Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy by Tietze, Lutz F., Griesbach, Ulrich, Schuberth, Ingrid, Bothe, Ulrich, Marra, Alberto, Dondoni, Alessandro

“…The synthesis of the novel unprotected carboranyl C‐glycosides 2 and 20–24 starting from ethynyl C‐glycosides 1, 5–8, 10, and 13 is described. The new…”
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Ortho-Carboranyl Glycosides of Glucose, Mannose, Maltose and Lactose for Cancer Treatment by Boron Neutron-Capture Therapy by Tietze, Lutz F., Bothe, Ulrich

“…A short synthesis of novel carboranyl glycosides such as the one on the right for use in the treatment of cancer by boron neutron‐capture therapy is described…”
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Novel Carboranes with a DNA Binding Unit for the Treatment of Cancer by Boron Neutron Capture Therapy by Tietze, Lutz F., Griesbach, Ulrich, Bothe, Ulrich, Nakamura, Hiroyuki, Yamamoto, Yoshinori

“…The synthesis and biological evaluation of two ortho‐carborane derivatives which contain a 5,6,7‐trimethoxyindole (TMI) unit for use in boron neutron capture…”
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ortho-Carboranyl Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy by Tietze, Lutz F, Bothe, Ulrich, Griesbach, Ulrich, Nakaichi, Munekazu, Hasegawa, Toshinari, Nakamura, Hiroyuki, Yamamoto, Yoshinori

“…Distinct biological properties of the ortho-carboranyl (1,2-dicarba- closo-dodecaboranyl) glycosides 1, 2 and 3 were evaluated to estimate the suitability of…”
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Carboranyl Bisglycosides for the Treatment of Cancer by Boron Neutron Capture Therapy by Tietze, Lutz F., Bothe, Ulrich, Griesbach, Ulrich, Nakaichi, Munekazu, Hasegawa, Toshinari, Nakamura, Hiroyuki, Yamamoto, Yoshinori

“…Boron neutron capture therapy is a special type of radiotherapy for the treatment of cancer by using boron compounds. Problems often arise from the low water…”
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Preparation of a New Carboranyl Lactoside for the Treatment of Cancer by Boron Neutron Capture Therapy: Synthesis and Toxicity of Fluoro Carboranyl Glycosides for in vivo 19F-NMR Spectroscopy by Tietze, Lutz F., Bothe, Ulrich, Schuberth, Ingrid

“…The synthesis of new ortho‐carboranyl lactosides 8, 17, 19 and glucosides 22 and 23 for the use in boron neutron capture therapy is reported. Carboranyl…”
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