Search Results - "Botham, K.M"

Trigliceride-rich lipoproteins are taken up by macrophages differently via receptor-mediated pathways during the postprandial period by Sinausia, L, Cabello-Moruno, R, Botham, K.M, Montero, E, Perona, J.S

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Influence of chylomicron remnants on human monocyte activation in vitro by Bentley, C, Hathaway, N, Widdows, J, Bejta, F, De Pascale, C, Avella, M, Wheeler-Jones, C.P.D, Botham, K.M, Lawson, C

“…Abstract Background and aims Atherosclerosis is known to be an inflammatory disease and there is increasing evidence that chylomicron remnants (CMR), the…”
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The induction of macrophage foam cell formation by chylomicron remnants by Botham, K M, Moore, E H, De Pascale, C, Bejta, F

“…The accumulation of foam cells in the artery wall causes fatty streaks, the first lesions in atherosclerosis. LDL (low-density lipoprotein) plays a major role…”
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Protective responses of human endothelial cells to n−6 PUFA-containing chylomicron remnants are independent of particle oxidative state by Dalla-Riva, J., Elliott, J., Botham, K.M., Wheeler-Jones, C.P.D.

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Comparison of the effects of dietary saturated, mono-unsaturated and polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnant-like particles by Lopez-Soldado, I, Avella, M, Botham, K M

“…The effect of chylomicron remnant-like particles (CRLPs) enriched in saturated, mono-unsaturated or n-6 polyunsaturated fatty acids (derived from palm, olive…”
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Differential modulation of hepatic very low-density lipoprotein secretion by triacylglycerol-rich lipoproteins derived from different oleic-acid rich dietary oils by Perona, Javier S., Avella, Michael, Botham, Kathleen M., Ruiz-Gutierrez, Valentina

“…Minor components from dietary oils can modulate the atherogenic response of the TAG-rich lipoproteins (TRL) in which they are transported. In the present study…”
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Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: chylomicron remnants and their emerging roles in vascular dysfunction in atherosclerosis by Botham, K M, Wheeler-Jones, C P D

“…Although it has been known for many years that dietary lipids influence the development of atherosclerosis, in the past this has been attributed to their…”
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Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells by Perona, Javier S., Avella, Michael, Botham, Kathleen M., Ruiz-Gutierrez, Valentina

“…The fatty acid composition of dietary oils can modulate the incorporation of triacylglycerol-rich lipoproteins (TRL) into hepatocytes, thus affecting the…”
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Dietary fats induce human monocyte activation in vitro by Bentley, C, Bejta, F, De Pascale, C, Avella, M, Wheeler-Jones, C P D, Botham, K M, Lawson, C

“…In early atherosclerosis the frequency of activated monocytes in the peripheral circulation is amplified, and migration of monocytes into the walls of the…”
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Chylomicron-remnant-like particles modify production of vasoactive mediators by endothelial cells by Evans, M, Berhane, Y, Botham, K M, Elliott, J, Wheeler-Jones, C P D

“…Endothelial-cell dysfunction is a critical initiating event in the pathogenesis of atherosclerosis. Although there is evidence to suggest that chylomicron…”
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The fatty acid composition of chylomicron remnants influences their propensity to oxidate by Napolitano, M., Bravo, E., Avella, M., Chico, Y., Ochoa, B., Botham, K.M., Rivabene, R.

“…Abstract Although the replacement of saturated with unsaturated dietary fat has been advocated as a means of reducing the risk of cardiovascular disease, diets…”
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Met murine hepatocytes: A new model for the study of liver cholesterol metabolism by Botham, K.M., Amicone, L., Cavallari, C., Tripodi, M., Bravo, E.

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Preparation of chylomicron remnant-like particles for studying the effect of dietary lipids on vasoconstriction in porcine coronary arteries by Goulter, A.B., Avella, M.A., Elliott, J., Botham, K.M.

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The fatty acid composition of chylomicron remnants can alter their interaction with receptors on isolated hepatocytes by Lambert, M.S., Avella, M.A., Berhane, Y., Shervill, E., Botham, K.M.

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Induction of Macrophage Monocyte Chemoattractant Secretion by Triacylglycerol Rich Lipoproteins by Botham, K.M., Napolitano, M., Bravo, E.

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4.P.233 The uptake of chylomicron remnants and their effects on endothelial cell function in the perfused rat aorta by Grieve, D.J., Avella, M.A., Elliott, J., Botham, K.M.

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4.P.225 The influence of the type of dietary fat on the biliary excretion of chylomicron cholesterol in the rat in vivo by Botham, K.M., Avella, M.A., Cantafora, A., Bravo, E.

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3.P.160 The role of cyclic AMP-dependent protein kinase in the regulation of cholesteryl ester hydrolase in three human monocytic cell lines by Jones, A.K., Botham, K.M., Jackson, B., Suckling, K.E.

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4.P.238 Influence of the type of dietary fat on the biliary excretion of cholesterol from chylomicron remnants in the perfused liver by Lambert, M.S., Avella, M.A., Botham, K.M., Mayes, P.A.

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Down-Regulation of Macrophage Cytokine Secretion by Chylomicron Remnants: Role of the LDL Receptor by Botham, K.M., Graham, V.S., Lawson, C., Wheeler-Jones, C.P.D.

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