Search Results - "Botchkina, Inna"

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  1. 1

    Progesterone activates the principal Ca2+ channel of human sperm by Lishko, Polina V., Botchkina, Inna L., Kirichok, Yuriy

    Published in Nature (London) (17-03-2011)
    “…Progesterone's role in sperm The female steroid hormone progesterone is produced by the ovaries and the placenta, and supports gestation and embryogenesis…”
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    Journal Article
  2. 2

    Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel by Lishko, Polina V., Botchkina, Inna L., Fedorenko, Andriy, Kirichok, Yuriy

    Published in Cell (05-02-2010)
    “…Human spermatozoa are quiescent in the male reproductive system and must undergo activation once introduced into the female reproductive tract. This process is…”
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  3. 3

    Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA by SHANG LI, ROSENBERG, Jonathan E, DONJACOUR, Annemarie A, BOTCHKINA, Inna L, YUN KIT HOM, CUNHA, Gerald R, BLACKBURN, Elizabeth H

    Published in Cancer research (Chicago, Ill.) (15-07-2004)
    “…In human cancers, telomeres are commonly maintained by elevated levels of the ribonucleoprotein enzyme telomerase, which contains an intrinsic templating RNA…”
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  4. 4

    Phenotypic Subpopulations of Metastatic Colon Cancer Stem Cells: Genomic Analysis by Botchkina, Inna L, Rowehl, Rebecca A, Rivadeneira, David E, Karpeh, Jr, Martin S, Crawford, Howard, Dufour, Antoine, Ju, Jingfang, Wang, Yuan, Leyfman, Yan, Botchkina, Galina I

    Published in Cancer genomics & proteomics (2009)
    “…Background: Human cancer is characterized by high heterogeneity in gene expression, varieties of differentiation phenotypes and tumor-host interrelations…”
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  5. 5

    A Low Threshold Level of Expression of Mutant-Template Telomerase RNA Inhibits Human Tumor Cell Proliferation by Kim, Moses M., Rivera, Melissa A., Botchkina, Inna L., Shalaby, Refaat, Thor, Ann D., Blackburn, Elizabeth H.

    “…The ribonucleoprotein telomerase synthesizes telomeric DNA by copying an intrinsic RNA template. In most cancer cells, telomerase is highly activated. Here we…”
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  6. 6

    Noninvasive Detection of Prostate Cancer by Quantitative Analysis of Telomerase Activity by BOTCHKINA, Galina I, KIM, Roger H, BOTCHKINA, Inna L, KIRSHENBAUM, Alex, FRISCNER, Zelik, ADLER, Howard L

    Published in Clinical cancer research (01-05-2005)
    “…Purpose: Prostate cancer is the most common male malignancy and the second leading cause of male cancer death; therefore, there is urgent necessity for…”
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  7. 7

    Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers by Botchkina, Inna L, Rivadeneira, David E, Watkins, Kevin, Karpeh, Martin S, Botchkina, Galina I

    Published in Molecular medicine (Cambridge, Mass.) (01-01-2008)
    “…Early detection and accurate staging of gastrointestinal (GI) cancers are difficult. The aim of this study was to evaluate whether telomerase activity (TA) in…”
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  8. 8

    Highly sensitive revealing of PCR products with capillary electrophoresis based on single photon detection by Kabotyanski, Evgeni A., Botchkina, Inna L., Kosobokova, Olga, Botchkina, Galina I., Gorfinkel, Vera, Gorbovitski, Boris

    Published in Biosensors & bioelectronics (15-04-2006)
    “…Post-PCR fragment analysis was conducted using our single photon detection-based DNA sequencing instrument in order to substantially enhance the detection of…”
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  9. 9

    Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia by Botchkina, G I, Meistrell, 3rd, M E, Botchkina, I L, Tracey, K J

    Published in Molecular medicine (Cambridge, Mass.) (01-11-1997)
    “…Cerebral ischemia induces a rapid and dramatic up-regulation of tumor necrosis factor (TNF) protein and mRNA, but the cellular sources of TNF in the ischemic…”
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  10. 10

    CNG-modulin: a novel Ca-dependent modulator of ligand sensitivity in cone photoreceptor cGMP-gated ion channels by Rebrik, Tatiana I, Botchkina, Inna, Arshavsky, Vadim Y, Craft, Cheryl M, Korenbrot, Juan I

    Published in The Journal of neuroscience (29-02-2012)
    “…The transduction current in several different types of sensory neurons arises from the activity of cyclic nucleotide-gated (CNG) ion channels. The channels in…”
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  11. 11
  12. 12

    Progesterone activates the principal Ca^sup 2+^ channel of human sperm by Lishko, Polina V, Botchkina, Inna L, Kirichok, Yuriy

    Published in Nature (London) (17-03-2011)
    “…Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg…”
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  13. 13