Search Results - "Botchkina, Inna"
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Progesterone activates the principal Ca2+ channel of human sperm
Published in Nature (London) (17-03-2011)“…Progesterone's role in sperm The female steroid hormone progesterone is produced by the ovaries and the placenta, and supports gestation and embryogenesis…”
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Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel
Published in Cell (05-02-2010)“…Human spermatozoa are quiescent in the male reproductive system and must undergo activation once introduced into the female reproductive tract. This process is…”
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Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA
Published in Cancer research (Chicago, Ill.) (15-07-2004)“…In human cancers, telomeres are commonly maintained by elevated levels of the ribonucleoprotein enzyme telomerase, which contains an intrinsic templating RNA…”
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Phenotypic Subpopulations of Metastatic Colon Cancer Stem Cells: Genomic Analysis
Published in Cancer genomics & proteomics (2009)“…Background: Human cancer is characterized by high heterogeneity in gene expression, varieties of differentiation phenotypes and tumor-host interrelations…”
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A Low Threshold Level of Expression of Mutant-Template Telomerase RNA Inhibits Human Tumor Cell Proliferation
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2001)“…The ribonucleoprotein telomerase synthesizes telomeric DNA by copying an intrinsic RNA template. In most cancer cells, telomerase is highly activated. Here we…”
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Noninvasive Detection of Prostate Cancer by Quantitative Analysis of Telomerase Activity
Published in Clinical cancer research (01-05-2005)“…Purpose: Prostate cancer is the most common male malignancy and the second leading cause of male cancer death; therefore, there is urgent necessity for…”
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Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers
Published in Molecular medicine (Cambridge, Mass.) (01-01-2008)“…Early detection and accurate staging of gastrointestinal (GI) cancers are difficult. The aim of this study was to evaluate whether telomerase activity (TA) in…”
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Highly sensitive revealing of PCR products with capillary electrophoresis based on single photon detection
Published in Biosensors & bioelectronics (15-04-2006)“…Post-PCR fragment analysis was conducted using our single photon detection-based DNA sequencing instrument in order to substantially enhance the detection of…”
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Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia
Published in Molecular medicine (Cambridge, Mass.) (01-11-1997)“…Cerebral ischemia induces a rapid and dramatic up-regulation of tumor necrosis factor (TNF) protein and mRNA, but the cellular sources of TNF in the ischemic…”
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CNG-modulin: a novel Ca-dependent modulator of ligand sensitivity in cone photoreceptor cGMP-gated ion channels
Published in The Journal of neuroscience (29-02-2012)“…The transduction current in several different types of sensory neurons arises from the activity of cyclic nucleotide-gated (CNG) ion channels. The channels in…”
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Progesterone activates the principal [Ca.sup.2+] channel of human sperm
Published in Nature (London) (17-03-2011)Get full text
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12
Progesterone activates the principal Ca^sup 2+^ channel of human sperm
Published in Nature (London) (17-03-2011)“…Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg…”
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13
Acid Extrusion from Human Spermatozoa is Mediated by Flagellar Hv1 Proton Channel
Published in Biophysical journal (01-01-2010)Get full text
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