Search Results - "Botchan, M R"

The minichromosome maintenance replicative helicase by Bell, Stephen D, Botchan, Michael R

“…The eukaryotic replicative helicase, the minichromosome maintenance (MCM) complex, is composed of six distinct, but related, subunits MCM(2-7). The…”
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Orc mutants arrest in metaphase with abnormally condensed chromosomes by Pflumm, M F, Botchan, M R

“…The origin recognition complex (ORC) is a six subunit complex required for eukaryotic DNA replication initiation and for silencing of the heterochromatic…”
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The retinoblastoma gene product regulates Sp1-mediated transcription by Kim, S J, Onwuta, U S, Lee, Y I, Li, R, Botchan, M R, Robbins, P D

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Crystal Structure of the Human Papillomavirus Type 18 E2 Activation Domain by Harris, Seth F., Botchan, Michael R.

“…The papillomavirus E2 protein regulates viral transcription and DNA replication through interactions with cellular and viral proteins. The amino-terminal…”
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Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1 by Li, R, Botchan, M.R

“…The papillomavirus E2 transcription factor is directly involved in viral DNA replication. Previous studies have shown that E2 interacts with both the viral E1…”
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DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding by Remus, Dirk, Beall, Eileen L, Botchan, Michael R

“…Drosophila origin recognition complex (ORC) localizes to defined positions on chromosomes, and in follicle cells the chorion gene amplification loci are…”
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Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription by Li, R, Knight, J D, Jackson, S P, Tjian, R, Botchan, M R

“…The physical interaction of heterologous site-specific DNA-binding proteins is an important theme in eukaryotic transcriptional regulation. In this paper, we…”
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Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator by Mohr, I.J. (University of California, Berkely, CA), Clark, R, Sun, S, Androphy, E.J, MacPherson, P, Botchan, M.R

“…The mechanism by which transcription factors stimulate DNA replication in eukaryotes is unknown. Bovine papillomavirus DNA synthesis requires the products of…”
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p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner by Chesnokov, Igor, Chu, Wen-Ming, Botchan, Michael R., Schmid, Carl W.

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A Drosophila Homolog of the Yeast Origin Recognition Complex by Gossen, Manfred, Daniel T. S. Pak, Hansen, Stig K., Acharya, Jairaj K., Botchan, Michael R.

“…Genes for Drosophila melanogaster have been identified that encode proteins homologous to Orc2p and Orc5p of the Saccharomyces cerevisiae origin recognition…”
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The Cellular DNA Polymerase α-Primase is Required for Papillomavirus DNA Replication and Associates with the Viral E1 Helicase by Park, Peter, Copeland, William, Yang, Liu, Wang, Teresa, Botchan, Michael R., Mohr, Ian J.

“…Persistent infection by papillomaviruses involves the maintenance of viral DNA as a nuclear plasmid, the replication of which requires host DNA polymerases…”
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DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects by Thorner, L.K, Lim, D.A, Botchan, M.R

“…The E1 protein of bovine papillomavirus type 1 is a multifunctional enzyme required for papillomaviral DNA replication. It assists in the initiation of…”
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Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors by LUSKY, M, BOTCHAN, M. R

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Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication by Ferguson, M.K. (University of California, Berkeley, CA.), Botchan, M.R

“…The bovine papillomavirus protein E2 serves dual functions in viral transcription and in the initiation of viral replication. As a transcription factor, E2 can…”
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The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site by LENTZ, M. R, PAK, D, MOHR, I, BOTCHAN, M. R

“…Bovine papillomavirus (BPV) DNA replication occurs in the nucleus of infected cells. Most enzymatic activities are carried out by host cell proteins, with the…”
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cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin by Russell, J, Botchan, M R

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The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication by Li, R, Botchan, M R

“…For papillomavirus DNA replication, the E2 enhancer protein cooperatively assists in binding of the E1 helicase to the origin. We report that, at limiting E1…”
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Role for a Drosophila Myb-containing protein complex in site-specific DNA replication by Botchan, Michael R, Beall, Eileen L, Manak, J. Robert, Zhou, Sharleen, Bell, Maren, Lipsick, Joseph S

“…There is considerable interest in the developmental, temporal and tissue-specific patterns of DNA replication in metazoans. Site-specific DNA replication at…”
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High Mutation Frequency in DNA Transfected into Mammalian Cells by Calos, Michele P., Lebkowski, Jane S., Botchan, Michael R.

“…The lacI gene of Escherichia coli was used to score mutation in mammalian cells of simian virus 40-based recombinant DNA vectors that provide for replication…”
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Transient replication of bovine papilloma virus type 1 plasmids: cis and trans requirements by Lusky, M, Botchan, M.R

“…A transient assay has been used to study bovine papilloma virus type 1 (BPV-1) replication. We show that BPV-1 early replication occurs faster than cellular…”
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