Search Results - "Botana, Luis M."

An overview of the effective combination therapies for the treatment of breast cancer by Núñez, Cristina, Capelo, José Luis, Igrejas, Gilberto, Alfonso, Amparo, Botana, Luis M, Lodeiro, Carlos

“…Abstract Breast cancer (BC) is generally classified based on the receptors overexpressed on the cell nucleus, which include hormone receptors such as…”
Get full text

From Marine Origin to Therapeutics: The Antitumor Potential of Marine Algae-Derived Compounds by Alves, Celso, Silva, Joana, Pinteus, Susete, Gaspar, Helena, Alpoim, Maria C, Botana, Luis M, Pedrosa, Rui

“…Marine environment has demonstrated to be an interesting source of compounds with uncommon and unique chemical features on which the molecular modeling and…”
Get full text

A QuEChERS based extraction procedure coupled to UPLC-MS/MS detection for mycotoxins analysis in beer by González-Jartín, Jesús M., Alfonso, Amparo, Rodríguez, Inés, Sainz, María J., Vieytes, Mercedes R., Botana, Luis M.

“…•A new method was developed for the analysis of mycotoxins in beer.•The method allows the identification and quantification of 23 mycotoxins.•A QuEChERS…”
Get full text

Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection by Vilariño, Natalia, Louzao, M Carmen, Abal, Paula, Cagide, Eva, Carrera, Cristina, Vieytes, Mercedes R, Botana, Luis M

“…Marine biotoxins are produced by aquatic microorganisms and accumulate in shellfish or finfish following the food web. These toxins usually reach human…”
Get full text

A single run UPLC-MS/MS method for detection of all EU-regulated marine toxins by Rodríguez, Inés, Alfonso, Amparo, González-Jartín, Jesús M., Vieytes, Mercedes R., Botana, Luis M.

“…A UPLC-MS/MS method has been developed for identification and quantification of hydrophilic and lipophilic marine toxins. The method included the determination…”
Get full text

Current Trends and New Challenges in Marine Phycotoxins by Louzao, Maria Carmen, Vilariño, Natalia, Vale, Carmen, Costas, Celia, Cao, Alejandro, Raposo-Garcia, Sandra, Vieytes, Mercedes R, Botana, Luis M

“…Marine phycotoxins are a multiplicity of bioactive compounds which are produced by microalgae and bioaccumulate in the marine food web. Phycotoxins affect the…”
Get full text

Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides by Bornancin, Louis, Alonso, Eva, Alvariño, Rebeca, Inguimbert, Nicolas, Bonnard, Isabelle, Botana, Luis M., Banaigs, Bernard

“…[Display omitted] Five new laxaphycins were isolated and fully characterised from the bloom forming cyanobacteria Anabaena torulosa sampled from Moorea, French…”
Get full text

Cyclophilins A, B, and C Role in Human T Lymphocytes Upon Inflammatory Conditions by Gegunde, Sandra, Alfonso, Amparo, Alvariño, Rebeca, Alonso, Eva, Botana, Luis M

“…Cyclophilins (Cyps) are a group of peptidyl-prolyl isomerases that play crucial roles in regulatory mechanisms of cellular physiology and pathology in several…”
Get full text

LC-MS/MS Analysis of the Emerging Toxin Pinnatoxin-G and High Levels of Esterified OA Group Toxins in Galician Commercial Mussels by Otero, Paz, Miguéns, Natalia, Rodríguez, Inés, Botana, Luis M

“…The occurrence of marine harmful algae is increasing worldwide and, therefore, the accumulation of lipophilic marine toxins from harmful phytoplankton…”
Get full text

Rapid analysis of paralytic shellfish toxins and tetrodotoxins by liquid chromatography-tandem mass spectrometry using a porous graphitic carbon column by Rey, Veronica, Botana, Ana M., Antelo, Alvaro, Alvarez, Mercedes, Botana, Luis M.

“…•A LC-MS/MS method with Hypercarb® column was optimized for PSTs and TTXs together.•It was possible to separate all PSTs, including GCs, from TTXs in 20 min.•A…”
Get full text

First Detection of Tetrodotoxin in Greek Shellfish by UPLC-MS/MS Potentially Linked to the Presence of the Dinoflagellate Prorocentrum minimum by Vlamis, Aristidis, Katikou, Panagiota, Rodriguez, Ines, Rey, Verónica, Alfonso, Amparo, Papazachariou, Angelos, Zacharaki, Thetis, Botana, Ana M, Botana, Luis M

“…During official shellfish control for the presence of marine biotoxins in Greece in year 2012, a series of unexplained positive mouse bioassays (MBA) for…”
Get full text

Toxic Action Reevaluation of Okadaic Acid, Dinophysistoxin-1 and Dinophysistoxin-2: Toxicity Equivalency Factors Based on the Oral Toxicity Study by Abal, Paula, Louzao, M. Carmen, Suzuki, Toshiyuki, Watanabe, Ryuichi, Vilariño, Natalia, Carrera, Cristina, Botana, Ana M., Vieytes, Mercedes R., Botana, Luis M.

“…Background/Aims: Okadaic acid (OA) and the structurally related compounds dinophysistoxin-1 (DTX1) and dinophysistoxin-2 (DTX2) are marine phycotoxins that…”
Get full text

Biological Activities of Cyclic and Acyclic B-Type Laxaphycins in SH-SY5Y Human Neuroblastoma Cells by Alvariño, Rebeca, Alonso, Eva, Bornancin, Louis, Bonnard, Isabelle, Inguimbert, Nicolas, Banaigs, Bernard, Botana, Luis M

“…Laxaphycins are a family of non-ribosomal lipopeptides that have been isolated from several cyanobacteria. Some of these compounds have presented cytotoxic…”
Get full text

Cyclophilin B serum levels present variations across the menstrual cycle by Alvariño, Rebeca, Gil-Mouce, Cristina, Botana, Manuel A., Gegunde, Sandra, González-Jartín, Jesús, Vieytes, Mercedes R., Alfonso, Amparo, Botana, Luis M.

“…Cyclophilins are a family of chaperones involved in inflammation and cell death. Cyclophilin B is released by inflammatory cells and acts through the receptor…”
Get full text

Mouse N2a Neuroblastoma Assay: Uncertainties and Comparison with Alternative Cell-Based Assays for Ciguatoxin Detection by Raposo-Garcia, Sandra, Cao, Alejandro, Costas, Celia, Louzao, M. Carmen, Vilariño, Natalia, Vale, Carmen, Botana, Luis M

“…The growing concern about ciguatera fish poisoning (CF) due to the expansion of the microorganisms producing ciguatoxins (CTXs) increased the need to develop a…”
Get full text

New gastropod vectors and tetrodotoxin potential expansion in temperate waters of the Atlantic Ocean by Silva, Marisa, Azevedo, Joana, Rodriguez, Paula, Alfonso, Amparo, Botana, Luis M, Vasconcelos, Vítor

“…Tetrodotoxin is a potent low weight marine toxin found in warm waters, especially of the Indian and Pacific Oceans. Intoxications are usually linked to the…”
Get full text

Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from Sphaerococcus coronopifolius by Alves, Celso, Silva, Joana, Pinteus, Susete, Alonso, Eva, Alvariño, Rebeca, Duarte, Adriana, Marmitt, Diorge, Goettert, Márcia Inês, Gaspar, Helena, Alfonso, Amparo, Alpoim, Maria C, M Botana, Luis, Pedrosa, Rui

“…Marine natural products have exhibited uncommon chemical structures with relevant antitumor properties highlighting their potential to inspire the development…”
Get full text

Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast) by Silva, Marisa, Rodríguez, Inés, Barreiro, Aldo, Kaufmann, Manfred, Neto, Ana Isabel, Hassouani, Meryem, Sabour, Brahim, Alfonso, Amparo, Botana, Luis M, Vasconcelos, Vitor

“…Tetrodotoxin (TTX) is a potent alkaloid typically from tropical ecosystems, but in the last decade its presence has been more pronounced in the temperate…”
Get full text

A Perspective on the Toxicology of Marine Toxins by Botana, Luis M

“…Although there has been much progress with regard to marine toxins from dinoflagellates, much remains to be done. Because these compounds are a seafood…”
Get full text

First Toxicity Report of Tetrodotoxin and 5,6,11-TrideoxyTTX in the Trumpet Shell Charonia lampas lampas in Europe by Rodriguez, Paula, Alfonso, Amparo, Vale, Carmen, Alfonso, Carmen, Vale, Paulo, Tellez, Antonio, Botana, Luis M

“…Tetrodotoxin (TTX) is one of the most potent toxins already isolated, which occurs in a wide variety of animals. In this work, the occurrence of TTX and…”
Get full text