Search Results - "Bot, Stéphanie"
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Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Published in Journal of medicinal chemistry (13-01-2011)“…A novel series of 3-aryl-phospho-indole (API) non-nucleoside reverse transcriptase inhibitors of HIV-1 was developed. Chemical variation in the phosphorus…”
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Journal Article -
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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor
Published in Journal of medicinal chemistry (10-03-2016)“…Here, we describe the design, synthesis, biological evaluation, and identification of a clinical candidate non-nucleoside reverse transcriptase inhibitors…”
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Journal Article -
3
Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate
Published in Organic process research & development (16-02-2018)“…A new and improved synthetic route to an intermediate in the synthesis of the phosphinate ester GSK2248761A is described. In the key step, we describe the…”
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Journal Article -
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The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors
Published in Bioorganic & medicinal chemistry letters (15-09-2017)“…[Display omitted] Herein we describe the discovery of IDX21437 35b, a novel RPd-aminoacid-based phosphoramidate prodrug of 2′-α-chloro-2′-β-C-methyluridine…”
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Journal Article -
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Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor
Published in Bioorganic & medicinal chemistry letters (01-06-2017)“…[Display omitted] Hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase (RdRp) plays a central role in virus replication. NS5B has no functional equivalent…”
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REISER, Christa, REFLECTIONS ON ANGER: Women and Men in a Changing Society
Published in Journal of comparative family studies (01-03-2002)Get full text
Journal Article -
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Overcoming My Model of Goodness as a Psychotherapist: Setting Boundaries-The Case of Tina
Published in Women & therapy (19-05-1997)“…The case of Tina is presented to examine one therapist's countertransference issues with a female client who had features of a Borderline Personality Disorder…”
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Journal Article -
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It's lonely at the top: An analysis of women's struggle with achievement
Published 01-01-1998“…Over the last few decades there has been much theoretical discussion but little empirical research exploring the relationship between women's intrapsychic…”
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Dissertation -
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Selective Functional Transformation of 1,2-Diols Via Organophosphorus Reagents
Published in Phosphorus, sulfur, and silicon and the related elements (01-01-1999)“…A new synthesis of 1,3,2λ 5 -dioxaphospholanes was realized by direct reaction of dibromotriphenylphosphorane with 1,2-diols. Ring opening studies were…”
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Journal Article -
10
REFLECTIONS ON ANGER: Women and Men in a Changing Society
Published in Journal of Comparative Family Studies (01-01-2002)“…Bot reviews "Reflections on Anger: Women and Men in a Changing Society" by Christa Reiser…”
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Book Review -
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Freudian Analysts/Feminist Issues
Published in Archives of sexual behavior (01-06-2002)“…Bot reviews "Freudian Analysts/Feminist Issues" by Judith Hughes…”
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Book Review -
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Reflections on anger: women and men in a changing society
Published in Journal of comparative family studies (01-01-2002)Get full text
Book Review