Search Results - "Boswell, Mikki"

Deconvoluting Wavelengths Leading to Fluorescent Light Induced Inflammation and Cellular Stress in Zebrafish (Danio rerio) by Boswell, Mikki, Boswell, William, Lu, Yuan, Savage, Markita, Walter, Ronald B.

“…Fluorescent light (FL) has been shown to induce a cellular immune and inflammatory response that is conserved over 450 MY of evolutionary divergence and among…”
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Peptoid Atropisomers by Paul, Bishwajit, Butterfoss, Glenn L, Boswell, Mikki G, Renfrew, P. Douglas, Yeung, Fanny G, Shah, Neel H, Wolf, Christian, Bonneau, Richard, Kirshenbaum, Kent

“…We report the isolation of N-aryl peptoid oligomers that adopt chiral folds, despite the absence of chiral centers. Peptoid monomers incorporating…”
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Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization model by Lu, Yuan, Boswell, Mikki, Boswell, William, Kneitz, Susanne, Klotz, Barbara, Savage, Markita, Salinas, Raquel, Marks, Rebecca, Regneri, Janine, Postlethwait, John, Warren, Wesley C, Schartl, Manfred, Walter, Ronald

“…Understanding the genetic mechanisms underlying segregation of phenotypic variation through successive generations is important for understanding physiological…”
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Global assessment of organ specific basal gene expression over a diurnal cycle with analyses of gene copies exhibiting cyclic expression patterns by Lu, Yuan, Boswell, Mikki, Boswell, William, Salinas, Raquel Ybanez, Savage, Markita, Reyes, Jose, Walter, Sean, Marks, Rebecca, Gonzalez, Trevor, Medrano, Geraldo, Warren, Wesley C, Schartl, Manfred, Walter, Ronald B

“…Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution. Genes…”
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N-Naphthyl Peptoid Foldamers Exhibiting Atropisomerism by Paul, Bishwajit, Butterfoss, Glenn L, Boswell, Mikki G, Huang, Mia L, Bonneau, Richard, Wolf, Christian, Kirshenbaum, Kent

“…We introduce peptoid oligomers incorporating N-(1)-naphthyl glycine monomers. Axial chirality was established due to restricted rotation about the C–N(aryl)…”
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Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model by Lu, Yuan, Boswell, William, Boswell, Mikki, Klotz, Barbara, Kneitz, Susanne, Regneri, Janine, Savage, Markita, Mendoza, Cristina, Postlethwait, John, Warren, Wesley C., Schartl, Manfred, Walter, Ronald B.

“…Cell culture and protein target-based compound screening strategies, though broadly utilized in selecting candidate compounds, often fail to eliminate…”
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Waveband specific transcriptional control of select genetic pathways in vertebrate skin (Xiphophorus maculatus) by Walter, Ronald B, Boswell, Mikki, Chang, Jordan, Boswell, William T, Lu, Yuan, Navarro, Kaela, Walter, Sean M, Walter, Dylan J, Salinas, Raquel, Savage, Markita

“…Evolution occurred exclusively under the full spectrum of sunlight. Conscription of narrow regions of the solar spectrum by specific photoreceptors suggests a…”
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Intra-Strain Genetic Variation of Platyfish ( Xiphophorus maculatus ) Strains Determines Tumorigenic Trajectory by Lu, Yuan, Olivas, Taryn J, Boswell, Mikki, Boswell, William, Warren, Wes C, Schartl, Manfred, Walter, Ronald B

“…interspecies hybrids represent a valuable model system to study heritable tumorigenesis, and the only model system that exhibits both spontaneous and inducible…”
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Identification of robust hypoxia biomarker candidates from fin of medaka ( Oryzias latipes) by Zhang, Ziping, Wells, Melissa C., Boswell, Mikki G., Beldorth, Ion, Kirk, Lyndsey M., Wang, Yilei, Wang, Shulong, Savage, Markita, Walter, Ronald B., Booth, Rachell E.

“…Aquatic hypoxia caused by organic pollution and eutrophication is a pressing worldwide water pollution problem. Better methods for monitoring oxygen levels are…”
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Comparison of gene expression responses to hypoxia in viviparous ( Xiphophorus) and oviparous ( Oryzias) fishes using a medaka microarray by Boswell, Mikki G., Wells, Melissa C., Kirk, Lyndsey M., Ju, Zhenlin, Zhang, Ziping, Booth, Rachell E., Walter, Ronald B.

“…Gene expression profiling using DNA microarray technology is a useful tool for assessing gene transcript level responses after an organism is exposed to…”
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Transcriptional background effects on a tumor driver gene in different pigment cell types of medaka by Abdulsahib, Shahad, Boswell, William, Boswell, Mikki, Savage, Markita, Schartl, Manfred, Lu, Yuan

“…The Xiphophorus melanoma receptor kinase gene, xmrk, is a bona fide oncogene driving melanocyte tumorigenesis of Xiphophorus fish. When ectopically expressed…”
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Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility by Lu, Yuan, Sandoval, Angel, Voss, Sarah, Lai, Zhao, Kneitz, Susanne, Boswell, Will, Boswell, Mikki, Savage, Markita, Walter, Christi, Warren, Wes, Schartl, Manfred, Walter, Ronald

“…Mixing genomes of different species by hybridization can disrupt species-specific genetic interactions that were adapted and fixed within each species…”
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Segregation Between an Ornamental and a Disease Driver Gene Provides Insights Into Pigment Cell Regulation by Soria, Erika, Lu, Qiusheng, Boswell, Will, Du, Kang, Xing, Yanting, Boswell, Mikki, Weldon, Korri S, Lai, Zhao, Savage, Markita, Schartl, Manfred, Lu, Yuan

“…Genetic interactions are adaptive within a species. Hybridization can disrupt such species-specific genetic interactions and creates novel interactions that…”
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The transcriptional response of skin to fluorescent light exposure in viviparous (Xiphophorus) and oviparous (Danio, Oryzias) fishes by Boswell, Mikki, Boswell, William, Lu, Yuan, Savage, Markita, Mazurek, Zachary, Chang, Jordan, Muster, Jeanot, Walter, Ronald

“…Differences in light sources are common in animal facilities and potentially can impact experimental results. Here, the potential impact of lighting…”
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High resolution genomes of multiple Xiphophorus species provide new insights into microevolution, hybrid incompatibility, and epistasis by Lu, Yuan, Rice, Edward, Du, Kang, Kneitz, Susanne, Naville, Magali, Dechaud, Corentin, Volff, Jean-Nicolas, Boswell, Mikki, Boswell, William, Hillier, LaDeana, Tomlinson, Chad, Milin, Kremitzki, Walter, Ronald B, Schartl, Manfred, Warren, Wesley C

“…Because of diverged adaptative phenotypes, fish species of the genus have contributed to a wide range of research for a century. Existing genome assemblies are…”
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Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactions by Lu, Yuan, Boswell, Mikki, Boswell, William, Kneitz, Susanne, Hausmann, Michael, Klotz, Barbara, Regneri, Janine, Savage, Markita, Amores, Angel, Postlethwait, John, Warren, Wesley, Schartl, Manfred, Walter, Ronald

“…Summary Comparative analysis of human and animal model melanomas can uncover conserved pathways and genetic changes that are relevant for the biology of cancer…”
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Characterization of basal gene expression trends over a diurnal cycle in Xiphophorus maculatus skin, brain and liver by Lu, Yuan, Reyes, Jose, Walter, Sean, Gonzalez, Trevor, Medrano, Geraldo, Boswell, Mikki, Boswell, William, Savage, Markita, Walter, Ronald

“…Evolutionarily conserved diurnal circadian mechanisms maintain oscillating patterns of gene expression based on the day-night cycle. Xiphophorus fish have been…”
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Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids by Lu, Yuan, Boswell, Mikki, Boswell, William, Kneitz, Susanne, Hausmann, Michael, Klotz, Barbara, Regneri, Janine, Savage, Markita, Amores, Angel, Postlethwait, John, Warren, Wesley, Schartl, Manfred, Walter, Ronald

“…Development of spontaneous melanoma in Xiphophorus interspecies backcross hybrid progeny, (X. hellerii × [X. maculatus Jp 163 A × X. hellerii]) is due to…”
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Molecular Genetic Response in Xiphophorus maculatus Skin upon Exposure to Various Wavebands of Light by Chang, Jordan, Lu, Yuan, Boswell, William, Boswell, Mikki, Caballero, Kaela, Walter, Ronald

“…Abstract only Xiphophorus fishes represent a vertebrate model to study the genetics associated with melanoma development. In particular, select interspecies…”
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Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin by Boswell, William, Boswell, Mikki, Titus, James, Savage, Markita, Lu, Yuan, Shen, Jianjun, Walter, Ronald B.

“…In both Xiphophorus fishes and humans, males are reported to have a higher incidence of melanoma than females. To better understand sex-specific differences in…”
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