Search Results - "Bossley, Cara J"

Post-acute COVID-19 outcomes in children requiring hospitalisation by Bossley, Cara J., Kavaliunaite, Ema, Harman, Katharine, Cook, James, Ruiz, Gary, Gupta, Atul

“…Post-acute COVID-19 causes long term sequalae in adults. This is less well described in children. We performed clinical assessments on a large cohort of…”
Get full text

Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines by Bossley, Cara J., Fleming, Louise, Gupta, Atul, Regamey, Nicolas, Frith, Jennifer, Oates, Timothy, Tsartsali, Lemonia, Lloyd, Clare M., Bush, Andrew, Saglani, Sejal

“…The pathology of pediatric severe therapy-resistant asthma (STRA) is little understood. We hypothesized that STRA in children is characterized by airway…”
Get full text

IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma by Saglani, Sejal, MD, Lui, Stephen, PhD, Ullmann, Nicola, MD, Campbell, Gaynor A., PhD, Sherburn, Rebekah T., MSc, Mathie, Sara A., MSc, Denney, Laura, PhD, Bossley, Cara J., MD(Res), Oates, Timothy, BSc, Walker, Simone A., BSc, Bush, Andrew, MD, Lloyd, Clare M., PhD

“…Background TH 2 cytokines are not responsible for the ongoing symptoms and pathology in children with severe therapy-resistant asthma (STRA). IL-33 induces…”
Get full text

Increased airway smooth muscle in preschool wheezers who have asthma at school age by O'Reilly, Ruth, MBChBBAO, Ullmann, Nicola, MD, Irving, Samantha, BSc, Bossley, Cara J., MBChB, Sonnappa, Samatha, PhD, Zhu, Jie, PhD, Oates, Timothy, BSc, Banya, Winston, BSc, Jeffery, Peter K., DSc, Bush, Andrew, MD, Saglani, Sejal, MD

“…Background Increased airway smooth muscle (ASM) is a feature of established asthma in schoolchildren, but nothing is known about ASM in preschool wheezers…”
Get full text

Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33 by Castanhinha, Susana, MD, Sherburn, Rebekah, MSc, Walker, Simone, BSc, Gupta, Atul, MD(Res), Bossley, Cara J., MD(Res), Buckley, James, PhD, Ullmann, Nicola, MD, Grychtol, Ruth, MD, Campbell, Gaynor, PhD, Maglione, Marco, MD, Koo, Sergio, MPH, Fleming, Louise, MD, Gregory, Lisa, PhD, Snelgrove, Robert J., PhD, Bush, Andrew, MD, Lloyd, Clare M., PhD, Saglani, Sejal, MD

“…Background The mechanism underlying severe asthma with fungal sensitization (SAFS) is unknown. IL-33 is important in fungus-induced asthma exacerbations, but…”
Get full text

Assessment of corticosteroid response in pediatric patients with severe asthma by using a multidomain approach by Bossley, Cara J., MD(Res), Fleming, Louise, MD, Ullmann, Nicola, MD, Gupta, Atul, MD(Res), Adams, Alexandra, MBBS, Nagakumar, Prasad, MBBS, Bush, Andrew, MD, Saglani, Sejal, MD

“…Background There is no agreed upon definition of systemic corticosteroid response in asthmatic children. Moreover, pediatric severe therapy-resistant asthma…”
Get full text

A meta-analysis of montelukast for recurrent wheeze in preschool children by Hussein, Hasan R., Gupta, Atul, Broughton, Simon, Ruiz, Gary, Brathwaite, Nicola, Bossley, Cara J.

“…There is conflicting evidence of the effectiveness of montelukast in preschool wheeze. A recent Cochrane review focused on its use in viral-induced wheeze;…”
Get full text

The utility of a multidomain assessment of steroid response for predicting clinical response to omalizumab by Fleming, Louise, MD, Koo, Maria, BSc, Bossley, Cara J., MD(Res), Nagakumar, Prasad, MBBS, Bush, Andrew, MD, Saglani, Sejal, MD

“…Characteristic Value Atopy 29 of 31 (94%) Sex: male:female 21:10 Age (y) 10 (6-15) Duration of symptoms (y) 9 (4.5-14) Weight (kg) 47.05 (21-84) Height (cm)…”
Get full text

A mysterious cause of chronic cough by Fereos, George, Buchanan, Charles, Allen, Pamela, Inusa, Baba, Bossley, Cara J

“…https://bit.ly/2GZAgmE…”
Get full text

Comparison of pulse oximetry and earlobe blood gas with CO-oximetry in children with sickle cell disease: a retrospective review by Arigliani, Michele, Zheng, Sean, Ruiz, Gary, Chakravorty, Subarna, Bossley, Cara J, Rees, David, Gupta, Atul

“…ObjectivesTo investigate the agreement between pulse oximetry (SpO2) and oxygen saturation (SaO2) measured by CO-oximetry on arterialised earlobe blood gas…”
Get full text

Passive tobacco smoke in children and young people during the COVID-19 pandemic by Osinibi, Mira, Gupta, Atul, Harman, Katharine, Bossley, Cara J

Get full text

Idiopathic pulmonary haemosiderosis by Gupta, Latika, Semple, Thomas, Padley, Simon, Bossley, Cara J

“…In this paper, we report the case of a boy in early childhood who presented with iron-deficiency anaemia, initially thought to be nutritional, who had a…”
Get more information

Nutritional status and pulmonary outcome in children and young people with cystic fibrosis by Papalexopoulou, Niovi, Dassios, Theodore G., Lunt, Alan, Bartlett, Fiona, Perrin, Felicity, Bossley, Cara J., Wyatt, Hilary A., Greenough, Anne

“…Nutrition is closely related to mortality and pulmonary and respiratory muscle function in cystic fibrosis (CF) patients. We initially validated results from a…”
Get full text

An observational study of the lung clearance index throughout childhood in cystic fibrosis: early years matter by Davies, Gwyneth, Stanojevic, Sanja, Raywood, Emma, Duncan, Julie A, Stocks, Janet, Lum, Sooky, Bush, Andrew, Viviani, Laura, Wade, Angie, Calder, Alistair, Owens, Catherine M, Goubau, Christophe, Carr, Siobhán B, Bossley, Cara J, Pao, Caroline, Aurora, Paul

“…The London Cystic Fibrosis Collaboration (LCFC) has prospectively followed a clinically diagnosed cohort of infants with cystic fibrosis (CF) born in South…”
Get full text

Higher oxygen saturation with hydroxyurea in paediatric sickle cell disease by van Geyzel, Lisa, Arigliani, Michele, Inusa, Baba, Singh, Bethany, Kozlowska, Wanda, Chakravorty, Subarna, Bossley, Cara J, Ruiz, Gary, Rees, David, Gupta, Atul

“…IntroductionSickle cell disease (SCD) is one of the most common inherited diseases worldwide. It is associated with lifelong morbidity and reduced life…”
Get full text

Long-term effectiveness of a staged assessment for paediatric problematic severe asthma by Sharples, James, Gupta, Atul, Fleming, Louise, Bossley, Cara J, Bracken-King, Marcella, Hall, Pippa, Hayward, Abigail, Puckey, Michelle, Balfour-Lynn, Ian M, Rosenthal, M, Bush, Andrew, Saglani, Sejal

Get full text

Interleukin-33 promotes airway remodelling in paediatric severe steroid resistant asthma by Saglani, Sejal, Lui, Stephen, Ullmann, Nicola, Campbell, Gaynor, Sherburn, Rebekah, Mathie, Sara, Denney, Laura, Bossley, Cara J, Oates, Timothy, Walker, Simone, Bush, Andrew, Lloyd, Clare M

Get full text

Pediatric severe asthma is characterized by eosinophilia and remodeling without TH 2 cytokines by Bossley, Cara J., MBChB, Fleming, Louise, MD, Gupta, Atul, MBBS, Regamey, Nicolas, MD, Frith, Jennifer, MBBS, Oates, Timothy, BSc, Tsartsali, Lemonia, MD, Lloyd, Clare M., PhD, Bush, Andrew, MD, Saglani, Sejal, MD

“…Background The pathology of pediatric severe therapy-resistant asthma (STRA) is little understood. Objectives We hypothesized that STRA in children is…”
Get full text

Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines by Bossley, Cara J, Fleming, Louise, Gupta, Atul, Regamey, Nicolas, Frith, Jennifer, Oates, Timothy, Tsartsali, Lemonia, Lloyd, Clare M, Bush, Andrew, Saglani, Sejal

“…The pathology of pediatric severe therapy-resistant asthma (STRA) is little understood. We hypothesized that STRA in children is characterized by airway…”
Get full text