Search Results - "Bossie, Cynthia"

Factors associated with relapse in schizophrenia despite adherence to long-acting injectable antipsychotic therapy by Alphs, Larry, Nasrallah, Henry A, Bossie, Cynthia A, Fu, Dong-Jing, Gopal, Srihari, Hough, David, Turkoz, Ibrahim

“…Many patients with schizophrenia will relapse despite uninterrupted antipsychotic (AP) long-acting therapy (LAT). This exploratory analysis examined variables…”
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Long-acting injectable versus daily oral antipsychotic treatment trials in schizophrenia: pragmatic versus explanatory study designs by Bossie, Cynthia A, Alphs, Larry D, Correll, Christoph U

“…Trial design characteristics related to the explanatory : pragmatic spectrum may contribute toward the inconsistent results reported in studies comparing…”
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Paliperidone Palmitate Once-Monthly Treatment in Recent Onset and Chronic Illness Patients With Schizoaffective Disorder by Bossie, Cynthia A, Turkoz, Ibrahim, Alphs, Larry, Mahalchick, Lucy, Fu, Dong-Jing

“…ABSTRACTData from a multiphase schizoaffective disorder study (NCT01193153) were used to examine the effects of paliperidone palmitate once-monthly (PP1M) by…”
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Relationship between the clinical global impression of severity for schizoaffective disorder scale and established mood scales for mania and depression by Turkoz, Ibrahim, Fu, Dong-Jing, Bossie, Cynthia A, Sheehan, John J, Alphs, Larry

“…Abstract Background This analysis explored the relationship between ratings on HAM-D-17 or YMRS and those on the depressive or manic subscale of CGI-S for…”
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Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial by Alphs, Larry, Bossie, Cynthia A, Sliwa, Jennifer K, Ma, Yi-Wen, Turner, Norris

“…This post hoc analysis (trial registration: ClinicalTrials.gov NCT00590577) assessed onset of efficacy and tolerability of acute treatment with once-monthly…”
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Rapid onset of treatment effects on psychosis, depression, and mania in patients with acute exacerbation of schizoaffective disorder following treatment with oral extended-release paliperidone by Fu, Dong-Jing, Turkoz, Ibrahim, Bossie, Cynthia A, Patel, Hiren, Alphs, Larry

“…Abstract Background Patients with schizoaffective disorder (SCA) experience complicated interplays of psychotic, depressive, and manic symptoms. Paliperidone…”
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Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysis by Turkoz, Ibrahim, Bossie, Cynthia A, Lindenmayer, Jean-Pierre, Schooler, Nina, Canuso, Carla M

“…To compare the efficacy and tolerability of paliperidone extended-release (ER) with risperidone immediate-release using propensity score methodology. Six…”
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Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial by Pandina, Gahan J, Bossie, Cynthia A, Youssef, Eriene, Zhu, Young, Dunbar, Fiona

“…Subgroup analysis of children (5-12 years) with autism enrolled in an 8-week, double-blind, placebo-controlled trial of risperidone for pervasive developmental…”
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Long-Acting Injectable Antipsychotics by Johnston, Karen, Sliwa, Jennifer Kern, Bossie, Cynthia A, Kim, Edward

“…To the Editor: We read with interest the article by Limandri (2019) entitled “Long-Acting Injectable Antipsychotic Medications: Why Aren't They Used as Often…”
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Body mass index and metabolic parameters in patients with schizophrenia during long-term treatment with paliperidone palmitate by Sliwa, Jennifer Kern, Fu, Dong-Jing, Bossie, Cynthia A, Turkoz, Ibrahim, Alphs, Larry

“…There is a strong association between weight gain and metabolic events in patients with schizophrenia receiving many of the second-generation antipsychotic…”
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Randomized, Double-Blind, Placebo-Controlled Study of Paliperidone Extended-Release and Quetiapine in Inpatients With Recently Exacerbated Schizophrenia by Canuso, Carla M., Dirks, Bryan, Carothers, Jennifer, Kosik-Gonzalez, Colette, Bossie, Cynthia A., Zhu, Young, Damaraju, C. V., Kalali, Amir H., Mahmoud, Ramy

“…Objective: The authors compared paliperidone extended-release and quetiapine in patients with recently exacerbated schizophrenia requiring hospitalization…”
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Paliperidone palmitate versus oral risperidone and risperidone long-acting injection in patients with recently diagnosed schizophrenia: a tolerability and efficacy comparison by Fu, Dong-Jing, Bossie, Cynthia A, Sliwa, Jennifer K, Ma, Yi-Wen, Alphs, Larry

“…Early in the course of illness, patients with schizophrenia may be particularly susceptible to adverse events (AEs). In this post-hoc, subgroup analysis of a…”
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Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial by Bossie, Cynthia A, Sliwa, Jennifer K, Ma, Yi-Wen, Fu, Dong-Jing, Alphs, Larry

“…Paliperidone palmitate is a long-acting injectable atypical antipsychotic for the acute and maintenance treatment of adults with schizophrenia. The recommended…”
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Effects of Risperidone Augmentation in Patients with Treatment-Resistant Depression: Results of Open-Label Treatment Followed by Double-Blind Continuation by Rapaport, Mark Hyman, Gharabawi, Georges M, Canuso, Carla M, Mahmoud, Ramy A, Keller, Martin B, Bossie, Cynthia A, Turkoz, Ibrahim, Lasser, Robert A, Loescher, Amy, Bouhours, Philippe, Dunbar, Fiona, Nemeroff, Charles B

“…Approximately one-third of persons with depression do not respond to antidepressant monotherapy. Studies suggest that atypical antipsychotic augmentation may…”
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A Randomized, Double-Blind, Placebo-Controlled Study of 2 Dose Ranges of Paliperidone Extended-Release in the Treatment of Subjects With Schizoaffective Disorder by CANUSO, Carla M, LINDENMAYER, Jean-Pierre, KOSIK-GONZALEZ, Colette, TURKOZ, Ibrahim, CAROTHERS, Jennifer, BOSSIE, Cynthia A, SCHOOLER, Nina R

“…This study was designed to assess efficacy and safety of paliperidone extended-release (ER) in patients with schizoaffective disorder. A randomized, 6-week,…”
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Remission in schizophrenia: Results from a 1-year study of long-acting risperidone injection by Lasser, Robert A., Bossie, Cynthia A., Gharabawi, Georges M., Kane, John M.

“…Although treatment advances have improved outcomes in schizophrenia, definitions of remission and recovery are still evolving. Recently proposed criteria for…”
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Effects of acute paliperidone palmitate treatment in subjects with schizophrenia recently treated with oral risperidone by Sliwa, Jennifer Kern, Bossie, Cynthia A, Ma, Yi-Wen, Alphs, Larry

“…Abstract Objective To examine efficacy and safety of acute treatment with paliperidone palmitate in subjects with schizophrenia whose disease remained…”
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ASPECT-R-A Tool to Rate the Pragmatic and Explanatory Characteristics of a Clinical Trial Design by Alphs, Larry D, Bossie, Cynthia A

“…Clinical and observational trials can be broadly categorized into having explanatory or pragmatic approaches with specific trial designs located somewhere…”
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Psychotic symptoms in patients with bipolar mania by Canuso, Carla M, Bossie, Cynthia A, Zhu, Young, Youssef, Eriene, Dunner, David L

“…Abstract Background Psychosis has been identified in as many as 68% of patients with bipolar mania. This analysis identified psychotic symptoms in these…”
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Placebo-Controlled Study of Relapse Prevention With Risperidone Augmentation in Older Patients with Resistant Depression by Alexopoulos, George S., M.D, Canuso, Carla M., M.D, Gharabawi, Georges M., M.D, Bossie, Cynthia A., Ph.D, Greenspan, Andrew, M.D, Turkoz, Ibrahim, M.S, Reynolds, Charles, M.D

“…Objective The effect of risperidone augmentation of citalopram for relapse prevention in older patients with antidepressant-resistant depression was evaluated…”
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