Search Results - "Bosserhoff, A"

Integrin β3 expression is regulated by let-7a miRNA in malignant melanoma by Müller, D W, Bosserhoff, A-K

“…Although integrin β 3 is known to play an important role in melanoma progression and invasion, regulation of integrin β 3 expression in melanoma has not been…”
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Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression by Braig, S, Bosserhoff, A-K

“…Bone morphogenetic proteins (BMPs) are known to play an important role in melanoma development and progression. However, the downstream targets of BMPs have…”
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Functional implication of BMP4 expression on angiogenesis in malignant melanoma by ROTHHAMMER, T, BATAILLE, F, SPRUSS, T, EISSNER, G, BOSSERHOFF, A.-K

“…Analyses of malignant melanomas revealed a strong expression of bone morphogenic proteins (BMPs) and their autocrine effect in promoting cell invasion and…”
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Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition by Dietrich, P, Kuphal, S, Spruss, T, Hellerbrand, C, Bosserhoff, A K

“…Malignant melanoma reveals rapidly increasing incidence and mortality rates worldwide. By now, BRAF inhibition is the standard therapy for advanced melanoma in…”
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Strong reduction of AGO2 expression in melanoma and cellular consequences by Völler, D, Reinders, J, Meister, G, Bosserhoff, A-K

“…Background: Processing of microRNAs (miRNAs) is a highly controlled process. Deregulation of miRNA expression was observed in several types of cancer but…”
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CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration by Braig, S, Wallner, S, Junglas, B, Fuchshofer, R, Bosserhoff, A-K

“…Background: Malignant melanoma cells are known to have altered expression of growth factors compared with normal human melanocytes. These changes most likely…”
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Slit-2 facilitates interaction of P-cadherin with Robo-3 and inhibits cell migration in an oral squamous cell carcinoma cell line by BAUER, Karin, DOWEJKO, Albert, BOSSERHOFF, A.-K, REICHERT, T. E, BAUER, Richard

“…Slits are a group of secreted glycoproteins that act as molecular guidance cues in cellular migration. Recently, several studies demonstrated that Slit-2 can…”
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MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression by Kappelmann, M, Kuphal, S, Meister, G, Vardimon, L, Bosserhoff, A-K

“…A fundamental event in the development and progression of malignant melanoma is the deregulation of cancer-relevant transcription factors. We recently showed…”
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The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation by Maurus, K, Hufnagel, A, Geiger, F, Graf, S, Berking, C, Heinemann, A, Paschen, A, Kneitz, S, Stigloher, C, Geissinger, E, Otto, C, Bosserhoff, A, Schartl, M, Meierjohann, S

“…The MAPK pathway is activated in the majority of melanomas and is the target of therapeutic approaches. Under normal conditions, it initiates the so-called…”
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Role of miRNAs in the progression of malignant melanoma by Mueller, D W, Bosserhoff, A K

“…Analysis of microRNA (miRNA) biogenesis and function is an area of research that started only recently but has subsequently accelerated tremendously. This is…”
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Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma by KUPHAL, S, BOSSERHOFF, A. K

“…E-cadherin is known to be an important molecule in epithelial-mesenchymal transition (EMT). Malignant transformation of melanocytes frequently attends with…”
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Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer by AUNG, P. P, OUE, N, MITANI, Y, NAKAYAMA, H, YOSHIDA, K, NOGUCHI, T, BOSSERHOFF, A. K, YASUI, W

“…Gastric cancer (GC) is one of the most common malignancies worldwide. Genes expressed only in cancer tissue will be useful molecular markers for diagnosis and…”
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Expression of Dickkopf genes is strongly reduced in malignant melanoma by KUPHAL, S, LODERMEYER, S, BATAILLE, F, SCHUIERER, M, HOANG, B. H, BOSSERHOFF, A. K

“…The Dickkopf (DKK) genes were originally identified as factors inducing head formation in Xenopus. The genes code for inhibitors that are involved in Wnt…”
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Integrated THz technology for label-free genetic diagnostics by Nagel, M., Haring Bolivar, P., Brucherseifer, M., Kurz, H., Bosserhoff, A., Büttner, R.

“…We report on a promising approach for the label-free analysis of DNA molecules using direct probing of the binding state of DNA with electromagnetic waves at…”
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P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation by Bauer, Karin, Dowejko, Albert, Bosserhoff, A.-K., Reichert, T.E., Josef Bauer, Richard

“…Cadherins belong to a family of Ca2+-dependent homophilic cell–cell adhesion proteins that are important for correct cellular localization and tissue…”
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Investigation of toxicity and mutagenicity of cold atmospheric argon plasma by Maisch, T., Bosserhoff, A. K., Unger, P., Heider, J., Shimizu, T., Zimmermann, J. L., Morfill, G. E., Landthaler, M., Karrer, S., Johnson, George

“…Cold atmospheric argon plasma is recognized as a new contact free approach for the decrease of bacterial load on chronic wounds in patients. So far very…”
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Loss of E-cadherin leads to upregulation of NFκB activity in malignant melanoma by KUPHAL, S, POSER, I, JOBIN, C, HELLERBRAND, C, BOSSERHOFF, A. K

“…Malignant transformation of melanocytes frequently coincides with loss of E-cadherin expression. Here, we show that loss of E-cadherin leads to induction of…”
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Reply to comment on: strong reduction of AGO2 expression in melanoma and cellular consequences by Völler, D, Bosserhoff, A

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Label-free probing of the binding state of DNA by time-domain terahertz sensing by Brucherseifer, M., Nagel, M., Haring Bolivar, P., Kurz, H., Bosserhoff, A., Büttner, R.

“…We present a promising approach for the label-free characterization of genetic material. Time-resolved terahertz (THz) transmission analysis of polynucleotides…”
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Protumoral roles of melanoma inhibitory activity 2 in oral squamous cell carcinoma by Kurihara, M, Kirita, T, Sasahira, T, Ohmori, H, Matsushima, S, Yamamoto, K, Bosserhoff, A K, Kuniyasu, H

“…Background: The role of melanoma inhibitory activity 2 (MIA2) was examined in human oral squamous cell carcinoma (OSCC). Methods: MIA2 role was examined by…”
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