Search Results - "Bosse, Kelly E"
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Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats
Published in Frontiers in behavioral neuroscience (30-04-2019)“…Medial prefrontal cortex (mPFC), amygdala, and striatum neurocircuitry has been shown to play an important role in post-traumatic stress disorder (PTSD)…”
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2
Aberrant striatal dopamine transmitter dynamics in brain-derived neurotrophic factor-deficient mice
Published in Journal of neurochemistry (01-02-2012)“…J. Neurochem. (2012) 120, 385–395. Brain‐derived neurotrophic factor (BDNF) modulates the synaptic transmission of several monoaminergic neuronal systems,…”
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3
Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice
Published in Neuroscience letters (11-02-2011)“…▶ Ethanol reduced striatal BDNF protein levels in wildtype and BDNF +/− mice. ▶ BDNF +/− mice had elevated baseline striatal dopamine levels by microdialysis…”
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4
The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum
Published in Neuropharmacology (01-10-2008)“…The highly selective delta opioid agonist, SNC80, elicits dopamine-related behaviors including locomotor stimulation and conditioned place-preference. In…”
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5
Anxiety-like Characteristics, Forepaw Thermal Sensitivity Changes and Glial Alterations 1 Month After Repetitive Blast Traumatic Brain Injury in Male Rats
Published in Annals of Neurosciences (12-08-2024)“…Many military service members are victims of repetitive blast traumatic brain injuries (rbTBI) and endure diverse altered psychological and behavioural…”
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6
Adenylyl Cyclase 1 Is Required for Ethanol-Induced Locomotor Sensitization and Associated Increases in NMDA Receptor Phosphorylation and Function in the Dorsal Medial Striatum
Published in The Journal of pharmacology and experimental therapeutics (01-11-2017)“…Neuroadaptive responses to chronic ethanol, such as behavioral sensitization, are associated with -methyl-D-aspartate receptor (NMDAR) recruitment. Ethanol…”
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7
Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8‐deficient mice
Published in Journal of neurochemistry (01-12-2015)“…The cAMP/protein kinase A pathway regulates methamphetamine (METH)‐induced neuroplasticity underlying behavioral sensitization. We hypothesize that adenylyl…”
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8
Cocaine-induced locomotor sensitization in rats correlates with nucleus accumbens activity on manganese-enhanced MRI
Published in NMR in biomedicine (01-11-2015)“…A long‐standing goal of substance abuse research has been to link drug‐induced behavioral outcomes with the activity of specific brain regions to understand…”
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9
Calcium/calmodulin-stimulated adenylyl cyclases 1 and 8 regulate reward-related brain activity and ethanol consumption
Published in Brain imaging and behavior (01-04-2019)“…Evidence suggests a predictive link between elevated basal activity within reward-related networks (e.g., cortico-basal ganglia-thalamic networks) and…”
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10
Adenylyl cylases 1 and 8 mediate select striatal-dependent behaviors and sensitivity to ethanol stimulation in the adolescent period following acute neonatal ethanol exposure
Published in Behavioural brain research (01-08-2014)“…•Select striatal behaviors may be insensitive for detecting early alcohol exposure.•Adenylyl cyclase 1/8 moderate alcohol-induced activity after early alcohol…”
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11
Age-related murine hippocampal CA1 laminae oxidative stress measured in vivo by QUEnch-assiSTed (QUEST) MRI: impact of isoflurane anesthesia
Published in GeroScience (01-04-2020)“…Age-related impairments in spatial learning and memory often precede non-familial neurodegenerative disease. Ex vivo studies suggest that physiologic…”
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12
Synergistic activity between the delta-opioid agonist SNC80 and amphetamine occurs via a glutamatergic NMDA-receptor dependent mechanism
Published in Neuropharmacology (01-02-2014)“…Glutamate is known to cause the release of dopamine through a Ca2+-sensitive mechanism that involves activation of NMDA ionotropic glutamate receptors. In the…”
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13
Effects of agonists with mixed efficacy profiles at the mu and kappa opioid receptor on amphetamine‐mediated dopamine release
Published in The FASEB journal (01-03-2008)“…Abstract only Although studies have demonstrated that non‐selective, mixed kappa/mu opioid agonists attenuate stimulant self‐administration with fewer side…”
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14
The delta opioid agonist, SNC80, enhances amphetamine‐mediated release of dopamine through an action on glutamate neurotransmission
Published in The FASEB journal (2007)“…The delta opioid agonist SNC80 augments amphetamine (AMPH)‐mediated behaviors and AMPH‐mediated dopamine release by a local action in the striatum, yet does…”
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15
The selective delta opioid agonist SNC80 increases amphetamine‐mediated release of dopamine
Published in The FASEB journal (01-03-2006)“…The delta opioid agonist SNC80 produces dopamine‐related behaviors including locomotor stimulation, antidepressant and anti‐Parkisonian like effects. In…”
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16
Effects of opioids on amphetamine-mediated dopamine efflux in rat striatum
Published 01-01-2008“…The psychostimulant, amphetamine, possesses abuse-related properties associated with the activation of central dopaminergic systems. Similarly, mu and delta…”
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