Search Results - "Bosse, Kelly"

Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats by Piggott, Veronica M, Bosse, Kelly E, Lisieski, Michael J, Strader, John A, Stanley, Jeffrey A, Conti, Alana C, Ghoddoussi, Farhad, Perrine, Shane A

“…Medial prefrontal cortex (mPFC), amygdala, and striatum neurocircuitry has been shown to play an important role in post-traumatic stress disorder (PTSD)…”
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Anxiety-like Characteristics, Forepaw Thermal Sensitivity Changes and Glial Alterations 1 Month After Repetitive Blast Traumatic Brain Injury in Male Rats by Kallakuri, Srinivasu, Sadik, Nareen, Davidson, Cameron J., Gheidi, Ali, Bosse, Kelly E., Bir, Cynthia A., Conti, Alana C., Perrine, Shane A.

“…Many military service members are victims of repetitive blast traumatic brain injuries (rbTBI) and endure diverse altered psychological and behavioural…”
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Adenylyl Cyclase 1 Is Required for Ethanol-Induced Locomotor Sensitization and Associated Increases in NMDA Receptor Phosphorylation and Function in the Dorsal Medial Striatum by Bosse, Kelly E, Oginsky, Max F, Susick, Laura L, Ramalingam, Sailesh, Ferrario, Carrie R, Conti, Alana C

“…Neuroadaptive responses to chronic ethanol, such as behavioral sensitization, are associated with -methyl-D-aspartate receptor (NMDAR) recruitment. Ethanol…”
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Aberrant striatal dopamine transmitter dynamics in brain-derived neurotrophic factor-deficient mice by Bosse, Kelly E., Maina, Francis K., Birbeck, Johnna A., France, Marion M., Roberts, Joseph J. P., Colombo, Michelle L., Mathews, Tiffany A.

“…J. Neurochem. (2012) 120, 385–395. Brain‐derived neurotrophic factor (BDNF) modulates the synaptic transmission of several monoaminergic neuronal systems,…”
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Synergistic activity between the delta-opioid agonist SNC80 and amphetamine occurs via a glutamatergic NMDA-receptor dependent mechanism by Bosse, Kelly E., Jutkiewicz, Emily M., Schultz-Kuszak, Kristin N., Mabrouk, Omar S., Kennedy, Robert T., Gnegy, Margaret E., Traynor, John R.

“…Glutamate is known to cause the release of dopamine through a Ca2+-sensitive mechanism that involves activation of NMDA ionotropic glutamate receptors. In the…”
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Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice by Bosse, Kelly E., Mathews, Tiffany A.

“…▶ Ethanol reduced striatal BDNF protein levels in wildtype and BDNF +/− mice. ▶ BDNF +/− mice had elevated baseline striatal dopamine levels by microdialysis…”
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Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8‐deficient mice by Bosse, Kelly E., Charlton, Jennifer L., Susick, Laura L., Newman, Brooke, Eagle, Andrew L., Mathews, Tiffany A., Perrine, Shane A., Conti, Alana C.

“…The cAMP/protein kinase A pathway regulates methamphetamine (METH)‐induced neuroplasticity underlying behavioral sensitization. We hypothesize that adenylyl…”
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Cocaine-induced locomotor sensitization in rats correlates with nucleus accumbens activity on manganese-enhanced MRI by Perrine, Shane A., Ghoddoussi, Farhad, Desai, Kirtan, Kohler, Robert J., Eapen, Ajay T., Lisieski, Michael J., Angoa-Perez, Mariana, Kuhn, Donald M., Bosse, Kelly E., Conti, Alana C., Bissig, David, Berkowitz, Bruce A.

“…A long‐standing goal of substance abuse research has been to link drug‐induced behavioral outcomes with the activity of specific brain regions to understand…”
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Calcium/calmodulin-stimulated adenylyl cyclases 1 and 8 regulate reward-related brain activity and ethanol consumption by Bosse, Kelly E., Ghoddoussi, Farhad, Eapen, Ajay T., Charlton, Jennifer L., Susick, Laura L., Desai, Kirt, Berkowitz, Bruce A., Perrine, Shane A., Conti, Alana C.

“…Evidence suggests a predictive link between elevated basal activity within reward-related networks (e.g., cortico-basal ganglia-thalamic networks) and…”
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Adenylyl cylases 1 and 8 mediate select striatal-dependent behaviors and sensitivity to ethanol stimulation in the adolescent period following acute neonatal ethanol exposure by Susick, Laura L., Lowing, Jennifer L., Bosse, Kelly E., Hildebrandt, Clara C., Chrumka, Alexandria C., Conti, Alana C.

“…•Select striatal behaviors may be insensitive for detecting early alcohol exposure.•Adenylyl cyclase 1/8 moderate alcohol-induced activity after early alcohol…”
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Age-related murine hippocampal CA1 laminae oxidative stress measured in vivo by QUEnch-assiSTed (QUEST) MRI: impact of isoflurane anesthesia by Berkowitz, Bruce A., Podolsky, Robert H., Childers, Karen Lins, Gow, Alexander, Schneider, Brandy L., Lloyd, Scott C., Bosse, Kelly E., Conti, Alana C., Roberts, Robin, Berri, Ali M., Graffice, Emma, Sinan, Kenan, Eliwat, Waleed, Shen, Yimin

“…Age-related impairments in spatial learning and memory often precede non-familial neurodegenerative disease. Ex vivo studies suggest that physiologic…”
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The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum by Bosse, Kelly E., Jutkiewicz, Emily M., Gnegy, Margaret E., Traynor, John R.

“…The highly selective delta opioid agonist, SNC80, elicits dopamine-related behaviors including locomotor stimulation and conditioned place-preference. In…”
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Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity by Greedy, Benjamin M, Bradbury, Faye, Thomas, Mark P, Grivas, Konstantinos, Cami-Kobeci, Gerta, Archambeau, Ashley, Bosse, Kelly, Clark, Mary J, Aceto, Mario, Lewis, John W, Traynor, John R, Husbands, Stephen M

“…Dual-acting kappa opioid receptor (KOR) agonist and mu opioid receptor (MOR) partial agonist ligands have been put forward as potential treatment agents for…”
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Effects of agonists with mixed efficacy profiles at the mu and kappa opioid receptor on amphetamine‐mediated dopamine release by Bosse, Kelly E, Bradbury, Faye A, Jutkiewicz, Emily M, Husbands, Steve M, Gnegy, Margaret E, Traynor, John R

“…Abstract only Although studies have demonstrated that non‐selective, mixed kappa/mu opioid agonists attenuate stimulant self‐administration with fewer side…”
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The delta opioid agonist, SNC80, enhances amphetamine‐mediated release of dopamine through an action on glutamate neurotransmission by Bosse, Kelly E, Jutkiewicz, Emily M, Gnegy, Margaret E, Traynor, John R

“…The delta opioid agonist SNC80 augments amphetamine (AMPH)‐mediated behaviors and AMPH‐mediated dopamine release by a local action in the striatum, yet does…”
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The selective delta opioid agonist SNC80 increases amphetamine‐mediated release of dopamine by Bosse, Kelly E, Jutkiewicz, Emily M, Gnegy, Margaret E, Traynor, John R

“…The delta opioid agonist SNC80 produces dopamine‐related behaviors including locomotor stimulation, antidepressant and anti‐Parkisonian like effects. In…”
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Effects of opioids on amphetamine-mediated dopamine efflux in rat striatum by Bosse, Kelly E

“…The psychostimulant, amphetamine, possesses abuse-related properties associated with the activation of central dopaminergic systems. Similarly, mu and delta…”
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