Search Results - "Bosler, David S"

Identification and interpretation of TET2 noncanonical splicing site intronic variants in myeloid neoplasm patients by Das, Riku, Tu, Zheng Jin, Bosler, David S., Cheng, Yu‐Wei

“…Background: DNA hypermethylation and instability due to inactivation mutations in Ten–eleven translocation 2 (TET2) is a key biomarker of hematological…”
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Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities by Braggio, Esteban, Dogan, Ahmet, Keats, Jonathan J, Chng, Wee J, Huang, Gaofeng, Matthews, Julie M, Maurer, Matthew J, Law, Mark E, Bosler, David S, Barrett, Michael, Lossos, Izidore S, Witzig, Thomas E, Fonseca, Rafael

“…Lymphoplasmacytic lymphomas and marginal zone lymphomas of nodal, extra-nodal and splenic types account for 10% of non-Hodgkin lymphomas. They are similar at…”
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Designing Myeloid Gene Panels: Evaluation of the Association for Molecular Pathology–Recommended Core 34-Gene Panel for Next-Generation Sequencing in Chronic Myeloid Neoplasms by Zhao, Fang, Bosler, David S, Cook, James R

“…(Arch Pathol Lab Med. 2022;146:1004-1011; doi: 10.5858/arpa.2021-0124-OA) Chronic myeloid neoplasms (CMNs) are a heterogeneous group of hematopoietic disorders…”
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Designing Myeloid Gene Panels by Zhao, Fang, Bosler, David S., Cook, James R.

“…Context.— Next-generation sequencing studies are increasingly used in the evaluation of suspected chronic myeloid neoplasms (CMNs), but there is wide…”
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Peripheral Blood and Bone Marrow Findings in Treatment-Naive Patients With Cytopenia(s)/Myeloid Neoplasms Harboring Both a Germline and a Somatic DDX41 Mutation by Bruehl, Frido K, Elbaz Younes, Ismail, Bosler, David S, Kelemen, Katalin, Jiang, Liuyan, Reichard, Kaaren K

“…DDX41-associated cytopenia(s)/myeloid neoplasms (DDX41-C/MNs) are an emerging pathologic entity. We examined the hematopathologic findings in DDX41-C/MNs with…”
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Clinically Significant CUX1 Mutations Are Frequently Subclonal and Common in Myeloid Disorders With a High Number of Co-mutated Genes and Dysplastic Features by Dermawan, Josephine K, Wensel, Christine, Visconte, Valeria, Maciejewski, Jaroslaw P, Cook, James R, Bosler, David S

“…CUX1 mutations have been reported in myeloid neoplasms. We aimed to characterize the mutational landscape, clonal architecture, and clinical characteristics of…”
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MGMT Methylation and Differential Survival Impact by Sex in Glioblastoma by Barnett, Addison E, Ozair, Ahmad, Bamashmos, Anas S, Li, Hong, Bosler, David S, Yeaney, Gabrielle, Ali, Assad, Peereboom, David M, Lathia, Justin D, Ahluwalia, Manmeet S

“…: Sex differences in glioblastoma (GBM) have been observed in incidence, genetic and epigenetic alterations, and immune response. These differences have…”
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A comprehensive analysis of cytopenias and bone marrow morphology in patients with a history of bariatric and metabolic surgery by Bruehl, Frido K., Bosler, David S., Butsch, W. Scott, Farkas, Daniel H., Ondrejka, Sarah L.

“…Introduction Following bariatric and metabolic surgery (BMS), patients may develop persistent cytopenia(s) despite adequate micronutrient levels. A…”
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Stem cell injection–induced glioneuronal lesion of the cauda equina by Lee, Bryan S, Achey, Rebecca L, Yeaney, Gabrielle A, Bosler, David S, Aly, Zarmeneh, Ontaneda, Daniel, Morren, John, Benzel, Edward C

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Myeloid Sarcoma Involving the Testis in Adults: Clonal Evolution of Acute Myeloid Leukemia by Nichols, Meredith M., Cook, James R., Bosler, David S., Rogers, Heesun J., Philip, John K.S.S., Jogenpally, Narender R., Reynolds, Jordan P., Robertson, Scott, Cotta, Claudiu V.

“…To describe the clinical, histologic, immunophenotypic, and genetic characteristics of myeloid sarcoma (MS) diagnosed in the testes of adults, 3 cases were…”
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A Model for Design and Implementation of a Laboratory Information-Management System Specific for Molecular Pathology Laboratory Operations by Tomlinson, Eban, Goodman, Jennifer, Loftus, Margaret, Bitto, Stephen, Carpenter, Erica, Oddo, Richard, Judis, LuAnn, Ali, Shabab, Robinson, Wyatt E., Carver, Miranda, Ganea, Mariana, McDonnell, Kristen, O'Neill, Diane, Starbuck, Jennifer, Johnson, Eric, Meister, Erik, Pohl, Jonathan, Spildener, Jessica, Shurtleff, Sheila, Sovie, Sheryl, Melendez, Cathleen, Krebs, Pamela, Riley, Jacquelyn D., Wensel, Christine, Astbury, Caroline, Azzato, Elizabeth M., Bosler, David S., Brock, Jay E., Cook, James R., Cheng, Yu-Wei, Tu, Zheng Jin, Cruise, Michael, Henricks, Walter H., Farkas, Daniel H.

“…The Molecular Pathology Section, Cleveland Clinic (Cleveland, OH), has undergone enhancement of its testing portfolio and processes. An Excel 2013– and…”
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Unusual case of calciphylaxis associated with metastatic breast carcinoma by BOSLER, David S, AMIN, Mitual B, GULLI, Farris, MALHOTRA, Rajwant K

“…Calciphylaxis is a relatively rare disorder associated with calcification of small- and medium-sized blood vessels, progressive ischemic skin necrosis, and…”
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Detection of T‐regulatory cells has a potential role in the diagnosis of classical Hodgkin lymphoma by Bosler, David S., Douglas‐Nikitin, Vonda K., Harris, Valerie N., Smith, Marc D.

“…Previous studies have demonstrated an increase in T‐regulatory cells in the involved lymph nodes and peripheral blood of patients with Hodgkin lymphoma. Our…”
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Chip-Derived Vs De Novo Treatment-Related Myeloid Neoplasms after Autologous Stem Cell Transplant for Lymphoid Disorders by Awada, Hussein, Gurnari, Carmelo, Visconte, Valeria, Kuzmanovic, Teodora, Awada, Hassan, Cook, James R., Bosler, David S., Bolwell, Brian J., Sobecks, Ronald M., Kalaycio, Matt, Maciejewski, Jaroslaw P.

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RUNX1 Germline Mutations of Autosomal-Dominant Familial Platelet Disorder Are More Common Than Expected in Adult Myeloid Leukemias Indicating Highly Variable Penetrance by Haddad, Christopher, Kubota, Yasuo, Bravo-Perez, Carlos, Gurnari, Carmelo, Guarnera, Luca, Ogbue, Olisaemeka, Durmaz, Arda, Nautiyal, Ishani, Mandala, Aashray, Bosler, David S., Carraway, Hetty E., Saunthararajah, Yogen, Visconte, Valeria, Maciejewski, Jaroslaw P.

“…Germline (GL) RUNX1 (RUNX1GL) mutations result in autosomal-dominant familial platelet disorder (FPD) and are associated with heightened risk of myeloid…”
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Compound Heterozygosity Involving Other Dead ( DDX) and Deah ( DHX) Box Helicases Explains Seemingly Monoallelic Somatic and Germline DDX41 Mutations by Visconte, Valeria, Bravo-Perez, Carlos, Durmaz, Arda, Guarnera, Luca, Nautiyal, Ishani, Reynold, Megan, Williams, Nakisha D, Kubota, Yasuo, Kawashima, Naomi, Kroger, Benjamin, Chung, Stephen S., Bosler, David S., Gurnari, Carmelo, Maciejewski, Jaroslaw P.

“…DDX41 mutations typify a seemingly distinct group of AML/MDS that appear to differ in many features from wild type entities. Classical DDX41 mutant myeloid…”
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Evaluation of the Association for Molecular Pathology-Recommended Core 34-Gene Panel for Next-Generation Sequencing in Chronic Myeloid Neoplasms by Zhao, Fang, Bosler, David S, Cook, James R

“…Context.--Next-generation sequencing studies are increasingly used in the evaluation of suspected chronic myeloid neoplasms (CMNs), but there is wide…”
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Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution by Ogbue, Olisaemeka, Kewan, Tariq, Mehkri, Omar, Fadell, Francois, Nautiyal, Ishani, Reynold, Megan, Durmaz, Arda, VanOudenhove, Jennifer, Awada, Hussein, Unlu, Serhan, Singh, Abhay, Visconte, Valeria, Mendez, Lourdes, Bosler, David S., Duggal, Abhijit, Halene, Stephanie, Maciejewski, Jaroslaw P., Al-Jaghbeer, Mohammed J, Gurnari, Carmelo

“…O.O & T.K are co-first authors. Clonal (myelo) hematopoiesis of indeterminate potential (CHIP) arises from somatic mutations in myeloid genes, providing a…”
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Myeloid Sarcoma Involving the Testis in Adults: Clonal Evolution of Acute Myeloid Leukemia by Nichols, Meredith M., Cook, James R., Bosler, David S., Rogers, Heesun J., Philip, John K.S.S., Jogenpally, Narender R., Reynolds, Jordan P., Robertson, Scott, Cotta, Claudiu V.

“…To describe the clinical, histologic, immunophenotypic, and genetic characteristics of myeloid sarcoma (MS) diagnosed in the testes of adults, 3 cases were…”
Get full text