Search Results - "Bose, Debojit"

cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response by Bose, Debojit

“…The last two decades have witnessed enormous growth in the field of cancer immunity. Mechanistic insights of cancer immunoediting have not only enhanced our…”
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The Tuberculosis Drug Streptomycin as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor by Bose, Debojit, Jayaraj, Gopal, Suryawanshi, Hemant, Agarwala, Prachi, Pore, Subrata Kumar, Banerjee, Rajkumar, Maiti, Souvik

“…No dice: MicroRNAs (miRNAs) fine‐tune gene expression, deregulation of which has been causally associated with a number of debilitating conditions…”
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Selective inhibition of miR-21 by phage display screened peptide by Bose, Debojit, Nahar, Smita, Rai, Manish Kumar, Ray, Arjun, Chakraborty, Kausik, Maiti, Souvik

“…miRNAs are nodal regulators of gene expression and deregulation of miRNAs is causally associated with different diseases, including cancer. Modulation of miRNA…”
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High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase by Ditzler, Mark A, Lange, Margaret J, Bose, Debojit, Bottoms, Christopher A, Virkler, Katherine F, Sawyer, Andrew W, Whatley, Angela S, Spollen, William, Givan, Scott A, Burke, Donald H

“…Systematic evolution of ligands through exponential enrichment (SELEX) is a well-established method for generating nucleic acid populations that are enriched…”
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Cyclic Cationic Peptides Containing Sugar Amino Acids Selectively Distinguishes and Inhibits Maturation of Pre-miRNAs of the Same Family by Nahar, Smita, Bose, Debojit, Pal, Sudip, Chakraborty, Tushar Kanti, Maiti, Souvik

“…The discovery of microRNAs (miRNAs) has added a new dimension to the gene regulatory networks, making aberrantly expressed miRNAs as therapeutically important…”
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Specificity of RSG-1.2 peptide binding to RRE-IIB RNA element of HIV-1 over Rev peptide is mainly enthalpic in origin by Kumar, Santosh, Bose, Debojit, Suryawanshi, Hemant, Sabharwal, Harshana, Mapa, Koyeli, Maiti, Souvik

“…Rev is an essential HIV-1 regulatory protein which binds to the Rev responsive element (RRE) present within the env gene of HIV-1 RNA genome. This binding…”
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RNA editing: Expanding the potential of RNA therapeutics by Booth, Brian J., Nourreddine, Sami, Katrekar, Dhruva, Savva, Yiannis, Bose, Debojit, Long, Thomas J., Huss, David J., Mali, Prashant

“…RNA therapeutics have had a tremendous impact on medicine, recently exemplified by the rapid development and deployment of mRNA vaccines to combat the COVID-19…”
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Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation by Bose, Debojit, Neumann, Alexander, Timmermann, Bernd, Meinke, Stefan, Heyd, Florian

“…T cells are nodal players in the adaptive immune response against pathogens and malignant cells. Alternative splicing plays a crucial role in T cell…”
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The Tuberculosis Drug Streptomycin as a Potential Cancer Therapeutic: Inhibition of miR-21 Function by Directly Targeting Its Precursor by Bose, Debojit, Jayaraj, Gopal, Suryawanshi, Hemant, Agarwala, Prachi, Pore, Subrata Kumar, Banerjee, Rajkumar, Maiti, Souvik

“…MikroRNAs (miRNAs) steuern die Genexprimierung, deren Deregulierung ursächlich mit einer Reihe von Erkrankungen verknüpft ist. Das pharmazeutische…”
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A Molecular-Beacon-Based Screen for Small Molecule Inhibitors of miRNA Maturation by Bose, Debojit, Jayaraj, Gopal Gunanathan, Kumar, Santosh, Maiti, Souvik

“…miRNAs are small non-coding RNAs that regulate about 60% of mammalian genes by modulating their transcript levels. Network scale studies of miRNA-mediated…”
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Anti-cancer therapeutic potential of quinazoline based small molecules via global upregulation of miRNAs by Nahar, Smita, Bose, Debojit, Kumar Panja, Sumit, Saha, Satyen, Maiti, Souvik

“…Three quinazoline based small molecules showed global upregulation of miRNA expression with a selective enrichment of tumor suppressor miRNAs. The target genes…”
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Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates by Ditzler, Mark A., Bose, Debojit, Shkriabai, Nikolozi, Marchand, Bruno, Sarafianos, Stefan G., Kvaratskhelia, Mamuka, Burke, Donald H.

“…A detailed understanding of how aptamers recognize biological binding partners is of considerable importance in the development of oligonucleotide…”
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