Search Results - "Boschero, C A"

Cafeteria diet inhibits insulin clearance by reduced insulin-degrading enzyme expression and mRNA splicing by Brandimarti, P, Costa-Júnior, J M, Ferreira, S M, Protzek, A O, Santos, G J, Carneiro, E M, Boschero, A C, Rezende, L F

“…Insulin clearance plays a major role in glucose homeostasis and insulin sensitivity in physiological and/or pathological conditions, such as obesity-induced…”
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Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance by Rezende, L. F., Santos, G. J., Santos-Silva, J. C., Carneiro, E. M., Boschero, A. C.

“…Aims/hypothesis Ciliary neurotrophic factor (CNTF) improves metabolic variables of obese animals with characteristics of type 2 diabetes, mainly by reducing…”
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Morphofunctional alterations in endocrine pancreas of short- and long-term dexamethasone-treated rats by Rafacho, A, Abrantes, J L F, Ribeiro, D L, Paula, F M, Pinto, M E, Boschero, A C, Bosqueiro, J R

“…Long-term dexamethasone therapy may induce peripheral insulin resistance (IR), which in turn elicits increased beta-cell function and proliferation. However,…”
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Glucose homoeostasis in rats exposed to acute intermittent hypoxia by Rafacho, A., Gonçalves-Neto, L. M., Ferreira, F. B. D., Protzek, A. O. P., Boschero, A. C., Nunes, E. A., Zoccal, D. B.

“…Aim Chronic exposure to intermittent hypoxia commonly induces the activation of sympathetic tonus and the disruption of glucose homoeostasis. However, the…”
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Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets by Carvalho, C. P. F., Barbosa, H. C. L., Britan, A., Santos-Silva, J. C. R., Boschero, A. C., Meda, P., Collares-Buzato, C. B.

“…Aims/hypothesis Cell–cell coupling mediated by gap junctions formed from connexin (CX) contributes to the control of insulin secretion in the endocrine…”
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adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment by Rafacho, A, Quallio, S, Ribeiro, D.L, Taboga, S.R, Paula, F.M.M, Boschero, A.C, Bosqueiro, J.R

“…Glucocorticoid administration induces insulin resistance (IR) and enhances islet mass and insulin secretion in rodents and humans. Here, we analysed whether…”
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Long-term taurine supplementation leads to enhanced hepatic steatosis, renal dysfunction and hyperglycemia in mice fed on a high-fat diet by Branco, R C S, Batista, T M, Camargo, R L, Borck, P C, Ribeiro, R A, Zoppi, C C, Lollo, P C B, Morato, P N, Boschero, A C, Carneiro, E M

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Pregnancy restores insulin secretion from pancreatic islets in cafeteria diet-induced obese rats by Vanzela, E C, Ribeiro, R A, de Oliveira, C A Machado, Rodrigues, F B, Bonfleur, M L, Carneiro, E M, Souza, K L A, Boschero, A C

“…Insulin resistance during pregnancy is counteracted by enhanced insulin secretion. This condition is aggravated by obesity, which increases the risk of…”
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Dexamethasone-induced insulin resistance is associated with increased connexin 36 mRNA and protein expression in pancreatic rat islets by Rafacho, A, Roma, L P, Taboga, S R, Boschero, A C, Bosqueiro, J R

“…Augmented glucose-stimulated insulin secretion (GSIS) is an adaptive mechanism exhibited by pancreatic islets from insulin-resistant animal models. Gap…”
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Overexpression of apolipoprotein CIII increases and CETP reverses diet-induced obesity in transgenic mice by Salerno, A.G, Silva, T.R, Amaral, M.E.C, Alberici, L.C, Bonfleur, M.L, Patricio, P.R, Francesconi, E.P.M.S, Grassi-Kassisse, D.M, Vercesi, A.E, Boschero, A.C

“…Objective: We recently described that hypertriglyceridemic apolipoprotein (apo) CIII transgenic mice show increased whole body metabolic rate. In this study,…”
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Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice by de Souza, J. C., de Oliveira, C. A. M., Carneiro, E. M., Boschero, A. C., de Oliveira, H. C. F.

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Peroxisome proliferator-activated receptor γ coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion by DE SOUZA, C. T, GASPARETTI, A. L, PEREIRA-DA-SILVA, M, ARAUJO, E. P, CARVALHEIRA, J. B, SAAD, M. J. A, BOSCHERO, A. C, CARNEIRO, E. M, VELLOSO, L. A

“…Sympathetic inputs inhibit insulin secretion through alpha2-adrenergic receptors coupled with Gi protein. High adrenergic tonus generated by exposure of…”
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Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery by Garcia, R. F, Gazola, V. A. F. G, Barrena, H. C, Hartmann, E. M, Berti, J, Toyama, M. H, Boschero, A. C, Carneiro, E. M, Manso, F. C, Bazotte, R. B

“…Our purpose was to determine the blood amino acid concentration during insulin induced hypoglycemia (IIH) and examine if the administration of alanine or…”
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Restoration of insulin secretion in pancreatic islets of protein-deficient rats by reduced expression of insulin receptor substrate (IRS)-1 and IRS-2 by Araujo, EP, Amaral, ME, Filiputti, E, De Souza, CT, Laurito, TL, Augusto, VD, Saad, MJ, Boschero, AC, Velloso, LA, Carneiro, EM

“…Autocrine and paracrine insulin signaling may participate in the fine control of insulin secretion. In the present study, tissue distribution and protein…”
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Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice by Carvalho, C P F, Oliveira, R B, Britan, A, Santos-Silva, J C, Boschero, A C, Meda, P, Collares-Buzato, C B

“…Gap junctional intercellular communication between β-cells is crucial for proper insulin biosynthesis and secretion. The aim of this work was to investigate…”
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Co-expression and regulation of connexins 36 and 43 in cultured neonatal rat pancreatic islets by Leite, A R, Carvalho, C P F, Furtado, A G, Barbosa, H C L, Boschero, A C, Collares-Buzato, C B

“…Fetal and neonatal pancreatic islets present a lower insulin secretory response as compared with adult islets. Prolonged culturing leads to an improvement of…”
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Short-term inhibition of peroxisome proliferator-activated receptor-γ coactivator-1α expression reverses diet-induced diabetes mellitus and hepatic steatosis in mice by DE SOUZA, C. T, ARAUJO, E. P, PRADA, P. O, SAAD, M. J. A, BOSCHERO, A. C, VELLOSO, L. A

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Circulating leukocyte heat shock protein 70 (HSP70) and oxidative stress markers in rats after a bout of exhaustive exercise by Antunes-Neto, J M F, Toyama, M H, Carneiro, E M, Boschero, A C, Pereira-da-Silva, L, Macedo, D V

“…A novel method to measure oxidative stress resulting from exhaustive exercise in rats is presented. In this new procedure we evaluated the erythrocyte…”
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Serum leptin and insulin levels in lactating protein-restricted rats: implications for energy balance by Ferreira, C. L. P., Macêdo, G. M., Latorraca, M. Q., Arantes, V. C., Veloso, R. V., Carneiro, E. M., Boschero, A. C., Nascimento, C. M. O., Gaíva, M. H.

“…The present study analysed the effect of protein restriction on serum insulin and leptin levels and their relationship with energy balance during lactation…”
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Oxotremorine-m potentiation of glucose-induced insulin release from rat islets involves M3 muscarinic receptors by Boschero, A C, Szpak-Glasman, M, Carneiro, E M, Bordin, S, Paul, I, Rojas, E, Atwater, I

“…cDNAs encoding for M1 and M3 muscarinic acetylcholine (ACh) receptors were detected in rat pancreatic islet cells by polymerase chain reaction (PCR)…”
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