Search Results - "Boschek, Curt B"

Identification of a Denitrase Activity against Calmodulin in Activated Macrophages Using High-Field Liquid Chromatography−FTICR Mass Spectrometry by Smallwood, Heather S, Lourette, Natacha M, Boschek, Curt B, Bigelow, Diana J, Smith, Richard D, Paša-Tolić, Ljiljana, Squier, Thomas C

“…We have identified a denitrase activity in macrophages that is upregulated following macrophage activation, which is shown by mass spectrometry to recognize…”
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Calcium Occupancy of N-Terminal Sites within Calmodulin Induces Inhibition of the Ryanodine Receptor Calcium Release Channel by Boschek, Curt B, Jones, Terry E, Squier, Thomas C, Bigelow, Diana J

“…Calmodulin (CaM) regulates calcium release from intracellular stores in skeletal muscle through its association with the ryanodine receptor (RyR1) calcium…”
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Molecular basis of the structural stability of a Top7-based scaffold at extreme pH and temperature conditions by Soares, Thereza A., Boschek, Curt B., Apiyo, David, Baird, Cheryl, Straatsma, T.P.

“…The development of stable biomolecular scaffolds that can tolerate environmental extremes has considerable potential for industrial and defense-related…”
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Controlled Activation of Protein Rotational Dynamics Using Smart Hydrogel Tethering by Beech, Brenda M, Xiong, Yijia, Boschek, Curt B, Baird, Cheryl L, Bigelow, Diana J, McAteer, Kathleen, Squier, Thomas C

“…Stimulus-responsive hydrogel materials that stabilize and control protein dynamics have the potential to enable a range of applications that take advantage of…”
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Different Conformational Switches Underlie the Calmodulin-Dependent Modulation of Calcium Pumps and Channels by Boschek, Curt B, Sun, Hongye, Bigelow, Diana J, Squier, Thomas C

“…We have used fluorescence spectroscopy to investigate the structure of calmodulin (CaM) bound with CaM-binding sequences of either the plasma membrane…”
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Disruption of Interdomain Interactions via Partial Calcium Occupancy of Calmodulin by Boschek, Curt B, Squier, Thomas C, Bigelow, Diana J

“…Binding of calcium to CaM exposes clefts in both N- and C-domains to promote their cooperative association with a diverse array of target proteins, functioning…”
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Loss of the Calmodulin-Dependent Inhibition of the RyR1 Calcium Release Channel upon Oxidation of Methionines in Calmodulin by Boschek, Curt B, Jones, Terry E, Smallwood, Heather S, Squier, Thomas C, Bigelow, Diana J

“…The oxidation of methionines in calmodulin (CaM) can affect the activity of calcium pumps and channels to modulate the amplitude and duration of calcium…”
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Engineering an ultra-stable affinity reagent based on Top7 by Boschek, Curt B., Apiyo, David O., Soares, Thereza A., Engelmann, Heather E., Pefaur, Noah B., Straatsma, Tjerk P., Baird, Cheryl L.

“…Antibodies are widely used for diagnostic and therapeutic applications because of their sensitive and specific recognition of a wide range of targets; however,…”
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Essential Role for Pro21 in Phospholamban for Optimal Inhibition of the Ca-ATPase by Li, Jinhui, Boschek, Curt B, Xiong, Yijia, Sacksteder, Colette A, Squier, Thomas C, Bigelow, Diana J

“…We have investigated the functional role of the flexible hinge region centered near the sequence TIEMP21, which connects the N-terminal cytosolic and…”
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Controlled Activation of Protein Rotational Dynamics using Smart Hydrogel Tethering by Xiong, Yijia, Beech, Brenda M., Boschek, Curt B., Baird, Cheryl L., Bigelow, Diana J., McAteer, Kathleen, Squier, Thomas C.

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Identification of Noninterfacial Amino Acids Important for Molecular Recognition in Calmodulin by Baird, Cheryl L., Beech, Brenda M., Boschek, Curt B., Xiong, Yijia, Smith, Dayle M., Squier, Thomas C.

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Loss of the Calmodulin-Dependent Inhibition of the RyR1 Calcium Release Channel upon Oxidation of Methionines in Calmodulin by Boschek, Curt B, Jones, Terry E, Smallwood, Heather S, Squier, Thomas C, Bigelow, Diana J

“…The oxidation of methionines in calmodulin (CaM) can affect the activity of calcium pumps and channels to modulate the amplitude and duration of calcium…”
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Different Conformational Switches Underlie the Calmodulin-Dependent Modulation of Calcium Pumps and Channels by Boschek, Curt B, Sun, Hongye, Bigelow, Diana J, Squier, Thomas C

“…We have used fluorescence spectroscopy to investigate the structure of calmodulin (CaM) bound with CaM-binding sequences of either the plasma membrane…”
Get full text

Essential Role for Pro 21 in Phospholamban for Optimal Inhibition of the Ca-ATPase by Li, Jinhui, Boschek, Curt B., Xiong, Yijia, Sacksteder, Colette A., Squier, Thomas C., Bigelow, Diana J.

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