Search Results - "Bosch–Marcé, Marta"

Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice by Sarkar, Kakali, Fox-Talbot, Karen, Steenbergen, Charles, Bosch-Marcé, Marta, Semenza, Gregg L

“…Diabetes is a major risk factor for ischemic disease. Treatment options for diabetic patients with peripheral arterial disease when revascularization is not…”
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Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice by Kong, Lingling, Wang, Xueyong, Choe, Dong W, Polley, Michelle, Burnett, Barrington G, Bosch-Marce, Marta, Griffin, John W, Rich, Mark M, Sumner, Charlotte J

“…The motor neuron disease spinal muscular atrophy (SMA) causes profound muscle weakness that most often leads to early death. At autopsy, SMA is characterized…”
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Sustained improvement of spinal muscular atrophy mice treated with trichostatin a plus nutrition by Narver, Heather L., Kong, Lingling, Burnett, Barrington G., Choe, Dong W., Bosch-Marcé, Marta, Taye, Addis A., Eckhaus, Michael A., Sumner, Charlotte J.

“…Early treatment with the histone deacetylase inhibitor, trichostatin A, plus nutritional support extended median survival of spinal muscular atrophy mice by…”
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Increased IGF-1 in muscle modulates the phenotype of severe SMA mice by BOSCH-MARCE, Marta, WEE, Claribel D, MARTINEZ, Tara L, LIPKES, Celeste E, CHOE, Dong W, LINGLING KONG, VAN MEERBEKE, James P, MUSARO, Antonio, SUMNER, Charlotte J

“…Spinal muscular atrophy (SMA) is an inherited motor neuron disease caused by the mutation of the survival motor neuron 1 (SMN1) gene and deficiency of the SMN…”
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Nitric oxide prevents axonal degeneration by inducing HIF-1-dependent expression of erythropoietin by Keswani, Sanjay C, Bosch-Marcé, Marta, Reed, Nicole, Fischer, Angela, Semenza, Gregg L, Höke, Ahmet

“…Nitric oxide (NO) is a signaling molecule that can trigger adaptive (physiological) or maladaptive (pathological) responses to stress stimuli in a…”
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Preclinical safety evaluation of human platelets treated with antimicrobial peptides in severe combined immunodeficient mice by Bosch-Marcé, Marta, Mohan, Ketha V.K., Gelderman, Monique P., Ryan, Patricia L., Russek-Cohen, Estelle, Atreya, Chintamani D.

“…Background Bacterial sepsis is a complication attributed to room temperature (RT)‐stored platelets (PLTs) in transfusion medicine. Antimicrobial peptides…”
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Leukoreduced whole blood–derived platelets treated with antimicrobial peptides maintain in vitro properties during storage by Bosch‐Marcé, Marta, Seetharaman, Shalini, Kurtz, James, Mohan, Ketha V.K., Wagner, Stephen J., Atreya, Chintamani D.

“…Background Bacterial sepsis is still a complication in patients transfused with stored platelets (PLTs). We have recently demonstrated that selected…”
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Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis by Titos, Esther, Clària, Joan, Bataller, RamóN, Bosch–Marcé, Marta, Ginès, Pere, Jiménez, Wladimiro, Arroyo, Vicente, Rivera, Francisca, Rodés, Joan

“…Background & Aims: The leukotrienes C4/D4/E4 (cysteinyl-LTs) are 5-lipoxygenase (5-LO)-derived eicosanoids with potent vasoconstrictor, proliferative, and…”
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Age-dependent VEGF expression and intraneural neovascularization during regeneration of peripheral nerves by Pola, Roberto, Aprahamian, Tamar R., Bosch-Marcé, Marta, Curry, Cynthia, Gaetani, Eleonora, Flex, Andrea, Smith, Roy C., Isner, Jeffrey M., Losordo, Douglas W.

“…The physiologic ability of peripheral nerves to regenerate after injury is impaired with aging. However, the mechanisms responsible for this phenomenon are…”
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Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia by Zhang, Huafeng, Bosch-Marce, Marta, Shimoda, Larissa A., Tan, Yee Sun, Baek, Jin Hyen, Wesley, Jacob B., Gonzalez, Frank J., Semenza, Gregg L.

“…Autophagy is a process by which cytoplasmic organelles can be catabolized either to remove defective structures or as a means of providing macromolecules for…”
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Heterozygous HIF‐1α deficiency impairs carotid body‐mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia by Peng, Ying‐Jie, Yuan, Guoxiang, Ramakrishnan, Deviprasadh, Sharma, Suresh D., Bosch‐Marce, Marta, Kumar, Ganesh K., Semenza, Gregg L., Prabhakar, Nanduri R.

“…Chronic intermittent hypoxia (CIH) occurs in patients with sleep apnoea and has adverse effects on multiple physiological functions. Previous studies have…”
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Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes by Hill, James M, Quenelle, Debra C, Cardin, Rhonda D, Vogel, Jodi L, Clement, Christian, Bravo, Fernando J, Foster, Timothy P, Bosch-Marce, Marta, Raja, Priya, Lee, Jennifer S, Bernstein, David I, Krause, Philip R, Knipe, David M, Kristie, Thomas M

“…Herpesviruses are highly prevalent and maintain lifelong latent reservoirs, thus posing challenges to the control of herpetic disease despite the availability…”
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Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia by Bosch-Marce, Marta, Okuyama, Hiroaki, Wesley, Jacob B, Sarkar, Kakali, Kimura, Hideo, Liu, Ye V, Zhang, Huafeng, Strazza, Marianne, Rey, Sergio, Savino, Lindsey, Zhou, Yi Fu, McDonald, Karin R, Na, Youn, Vandiver, Scott, Rabi, Alireza, Shaked, Yuval, Kerbel, Robert, LaVallee, Theresa, Semenza, Gregg L

“…Ischemia is a stimulus for production of angiogenic cytokines that activate local vascular cells and mobilize angiogenic cells to the circulation. These…”
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HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury by Feinman, Rena, Deitch, Edwin A, Watkins, Anthony C, Abungu, Billy, Colorado, Iriana, Kannan, Kolenkode B, Sheth, Sharvil U, Caputo, Francis J, Lu, Qi, Ramanathan, Madhuri, Attan, Shirhan, Badami, Chirag D, Doucet, Danielle, Barlos, Dimitrios, Bosch-Marce, Marta, Semenza, Gregg L, Xu, Da-Zhong

“…Acute lung injury (ALI) and the development of the multiple organ dysfunction syndrome (MODS) are major causes of death in trauma patients. Gut inflammation…”
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Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System by Vizcardo, Raul, Klemen, Nicholas D., Islam, S.M. Rafiqul, Gurusamy, Devikala, Tamaoki, Naritaka, Yamada, Daisuke, Koseki, Haruhiko, Kidder, Benjamin L., Yu, Zhiya, Jia, Li, Henning, Amanda N., Good, Meghan L., Bosch-Marce, Marta, Maeda, Takuya, Liu, Chengyu, Abdullaev, Zied, Pack, Svetlana, Palmer, Douglas C., Stroncek, David F., Ito, Fumito, Flomerfelt, Francis A., Kruhlak, Michael J., Restifo, Nicholas P.

“…Induced pluripotent stem cell (iPSC)-derived T cells may provide future therapies for cancer patients, but those generated by current methods, such as the…”
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Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization by YAMAGUCHI, Jun-Ichi, KUSANO, Kengo Fukushima, ASAHARA, Takayuki, MASUO, Osamu, KAWAMOTO, Atsuhiko, SILVER, Marcy, MURASAWA, Satoshi, BOSCH-MARCE, Marta, MASUDA, Haruchika, LOSORDO, Douglas W, ISNER, Jeffrey M

“…Stromal cell-derived factor-1 (SDF-1) is a chemokine considered to play an important role in the trafficking of hematopoietic stem cells. Given the close…”
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Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1 by Okuyama, Hiroaki, Krishnamachary, Balaji, Zhou, Yi Fu, Nagasawa, Hideko, Bosch-Marce, Marta, Semenza, Gregg L.

“…Bone marrow-derived cells are recruited to sites of ischemia, where they promote tissue vascularization. This response is dependent upon the expression of…”
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Spontaneous transformation of cultured mouse bone marrow-derived stromal cells by YI FU ZHOU, BOSCH-MARCE, Marta, OKUYAMA, Hiroaki, KRISHNAMACHARY, Balaji, KIMURA, Hideo, LI ZHANG, HUSO, David L, SEMENZA, Gregg L

“…Bone marrow-derived stromal cells have engendered interest because of their therapeutic potential for promoting tissue vascularization and repair. When…”
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Peripheral nerve ischemia: apolipoprotein E deficiency results in impaired functional recovery and reduction of associated intraneural angiogenic response by Pola, Roberto, Gaetani, Eleonora, Flex, Andrea, Aprahamian, Tamar, Proia, Anna S, Bosch-Marcé, Marta, Smith, Roy C, Pola, Paolo

“…Apolipoprotein E-knockout (apoE KO) mice have peripheral sensory nerve defects, reduced and delayed response to noxious thermal stimuli, abnormal morphology of…”
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Hyperhomocyst(e)inemia impairs angiogenesis in a murine model of limb ischemia by Bosch-Marcé, Marta, Pola, Roberto, Wecker, Andrea B, Silver, Marcy, Weber, Alberto, Luedemann, Corinne, Curry, Cynthia, Murayama, Toshinori, Kearney, Marianne, Yoon, Young-sup, Malinow, M René, Asahara, Takayuki, Isner, Jeffrey M, Losordo, Douglas W

“…Hyperhomocyst(e)inemia (HH) is an established independent risk factor for coronary, cerebral and peripheral vascular diseases. Recent studies have indicated…”
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