Search Results - "Bosch, Tessa"

Renal function after withdrawal of lithium by Hoekstra, Rocco, Lekkerkerker, Marius N., Kuijper, Tjallingius M., Bosch, Tessa M., Alphen, Arjan M.

“…Objectives Patients on chronic lithium therapy sometimes develop chronic kidney disease. For clinical decision–making, it is important to know whether…”
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Delayed Lithium Reintoxication in a Case of Severe Multidrug Intoxication: A Case Study by Liang, Jiayi, van den Bout, Christiaan J., Bosch, Tessa M., Mitrov-Winkelmolen, Lieke

“…The authors present a case of severe multidrug intoxication following massive ingestion of lithium, nortriptyline, aripiprazole, lorazepam, and temazepam…”
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Successful lithium treatment in a patient on hemodialysis by Engels, Noel, Alphen, Adriaan M., Bosch, Tessa M., Hoekstra, Rocco

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The added value of H2 antagonists in premedication regimens during paclitaxel treatment by Cox, Juul M., van Doorn, Leni, Malmberg, Ruben, Oomen-de Hoop, Esther, Bosch, Tessa M., van den Bemt, Patricia M. L. A., Boere, Ingrid A., Jager, Agnes, Mathijssen, Ron H. J., van Leeuwen, Roelof W. F.

“…Background Ranitidine, a histamine 2 blocker, is the standard of care to prevent hypersensitivity reactions (HSRs) caused by paclitaxel infusion. However, the…”
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Chronic kidney disease in lithium-treated patients, incidence and rate of decline by Van Alphen, Arjan M., Bosch, Tessa M., Kupka, Ralph W., Hoekstra, Rocco

“…Background Lithium-induced nephropathy is a known long-term complication, sometimes limiting the use of lithium as mood stabilizer. The aim of this study is to…”
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Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy by Bosch, Tessa M

“…There is wide variability in the response of individuals to standard doses of drug therapy. This is an important problem in clinical practice, where it can…”
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Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer by BOSCH, Tessa M, MEIJERMAN, Irma, BEIJNEN, Jos H, SCHELLENS, Jan H. M

“…There is wide variability in the response of individuals to standard doses of drug therapy. This is an important problem in clinical practice, where it can…”
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Pharmacogenetic Screening of CYP3A and ABCB1 in Relation to Population Pharmacokinetics of Docetaxel by BOSCH, Tessa M, HUITEMA, Alwin D. R, SCHELLENS, Jan H. M, DOODEMAN, Valerie D, JANSEN, Robert, WITTEVEEN, Els, SMIT, Wim M, JANSEN, Rob L, VAN HERPEN, Carla M, SOESAN, Marcel, BEIJNEN, Jos H

“…Purpose: Despite the extensive clinical experience with docetaxel, unpredictable interindividual variability in efficacy and toxicity remain important…”
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Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of ( )-[ C]verapamil and positron emission tomography by Toornvliet, Rolf, Berckel, Bart N.M., Luurtsema, Gert, Lubberink, Mark, Geldof, Albert A., Bosch, Tessa M., Oerlemans, Ruud, Lammertsma, Adriaan A., Franssen, Eric J.F.

“…Introduction P‐glycoprotein (P‐gp) is an efflux transporter responsible for the transport of various drugs across the blood‐brain barrier (BBB). Loss of P‐gp…”
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Adequacy of a hospital-wide standard dose of 7 mg/kg bodyweight gentamicin sufficient to achieve an adequate prophylactic maximum serum concentration ( Cmax ) in burn patients undergoing surgical burn wound treatment by Borra, Lennaert C.P, Bosch, Tessa M, van Baar, Margriet E, Dokter, Jan, Oen, Irma M, Ruijgrok, Elisabeth J

“…Highlights • Pharmacokinetics can be significantly altered in the burn patient. • We investigated whether this is relevant for prophylactic dosing of…”
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Adequacy of a hospital-wide standard dose of 7mg/kg bodyweight gentamicin sufficient to achieve an adequate prophylactic maximum serum concentration (Cmax) in burn patients undergoing surgical burn wound treatment by Borra, Lennaert C.P., Bosch, Tessa M., van Baar, Margriet E., Dokter, Jan, Oen, Irma M., Ruijgrok, Elisabeth J.

“…•Pharmacokinetics can be significantly altered in the burn patient.•We investigated whether this is relevant for prophylactic dosing of gentamicin.•90% (36/40)…”
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Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines by Brandon, Esther F.A., Bosch, Tessa M., Deenen, Maarten J., Levink, Rianne, van der Wal, Everdina, van Meerveld, Joyce B.M., Bijl, Monique, Beijnen, Jos H., Schellens, Jan H.M., Meijerman, Irma

“…Human cell lines are often used for in vitro biotransformation and transport studies of drugs. In vivo, genetic polymorphisms have been identified in…”
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Metabolism of trabectedin (ET-743, Yondelis™) in patients with advanced cancer by BEUMER, Jan H, RADEMAKER-LAKHAI, Jeany M, ROSING, Hilde, HILLEBRAND, Michel J. X, BOSCH, Tessa M, LOPEZ-LAZARO, Luis, SCHELLENS, Jan H. M, BEIJNEN, Jos H

“…Trabectedin (ET-743, Yondelis) is a novel anti-cancer drug currently undergoing phase II-III evaluation, that has shown remarkable activity in pre-treated…”
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Screening for polymorphisms in the PXR gene in a Dutch population by BOSCH, Tessa M, DEENEN, Maarten, PRUNTEL, Roelof, SMITS, Paul H. M, SCHELLENS, Jan H. M, BEIJNEN, Jos H, MEIJERMAN, Irma

“…Cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of over 50% of all drugs currently in use. However, CYP3A4 expression shows a large inter-individual…”
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Effects of Cyclosporine A on Single-Dose Pharmacokinetics of Intravenous Itraconazole in Patients With Hematologic Malignancies by Timmers, Gert Jan, Kessels, Lonneke W, Wilhelm, Abraham J, Veldkamp, Agnes I, Bosch, Tessa M, Beijnen, Jos H, Huijgens, Peter C

“…An open-label, clinical pilot study was performed to study the effect of cyclosporine A (CsA) on single-dose pharmacokinetics of itraconazole in patients with…”
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Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population by Bosch, Tessa M, Kjellberg, Linda M, Bouwers, Anja, Koeleman, Bobby P C, Schellens, Jan H M, Beijnen, Jos H, Smits, Paul H M, Meijerman, Irma

“…ABCG2 is a drug transporter involved in the protection of tissues by actively transporting toxic substances and xenobiotics out of cells. Cancer cells…”
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Antiviral activity of HIV type 1 protease inhibitors nelfinavir and indinavir in vivo is not influenced by P-glycoprotein activity on CD4+ T cells by Sankatsing, Sanjay U C, Cornelissen, Marion, Kloosterboer, Nico, Crommentuyn, Kristel M L, Bosch, Tessa M, Mul, Frederik P, Jurriaans, Suzanne, Huitema, Alwin D R, Beijnen, Jos H, Lange, Joep M A, Prins, Jan M, Schuitemaker, Hanneke

“…P-glycoprotein (P-gp) can compromise the antiretroviral effect of a protease inhibitor (PI)-containing regimen for HIV-1, but can also reduce HIV-1…”
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Rapid detection of the DPYD IVS14+1G>A mutation for screening patients to prevent fluorouracil-related toxicity by Bosch, Tessa M, Bakker, Remko, Schellens, Jan H M, Cats, Annemieke, Smits, Paul H M, Beijnen, Jos H

“…Deficiency of dihydropyrimidine dehydrogenase (DPD) has been linked to severe or lethal fluorouracil (FU)-related toxicity. The most prominent mutation in the…”
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European guidelines for workplace drug testing in oral fluid by Brcak, Michaela, Beck, Olof, Bosch, Tessa, Carmichael, Duncan, Fucci, Nadia, George, Claire, Piper, Mark, Salomone, Alberto, Schielen, Wim, Steinmeyer, Stefan, Taskinen, Sanna, Weinmann, Wolfgang

“…These guidelines for Legally Defensible Workplace Drug Testing have been prepared and updated by the European Workplace Drug Testing Society (EWDTS). The…”
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European guidelines for workplace drug testing in urine by Taskinen, Sanna, Beck, Olof, Bosch, Tessa, Brcak, Michaela, Carmichael, Duncan, Fucci, Nadia, George, Claire, Piper, Mark, Salomone, Alberto, Schielen, Wim, Steinmeyer, Stefan, Weinmann, Wolfgang

“…These European Guidelines for Workplace Drug Testing in Urine have been prepared and updated by the European Workplace Drug Testing Society (EWDTS). The first…”
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