Search Results - "Bosch, J. van den"

Exploratory Innovation, Exploitative Innovation, and Performance: Effects of Organizational Antecedents and Environmental Moderators by Jansen, Justin J. P, Van Den Bosch, Frans A. J, Volberda, Henk W

“…Research on exploration and exploitation is burgeoning, yet our understanding of the antecedents and consequences of both activities remains rather unclear. We…”
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Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function by Grevendonk, L., Connell, N. J., McCrum, C., Fealy, C. E., Bilet, L., Bruls, Y. M. H., Mevenkamp, J., Schrauwen-Hinderling, V. B., Jörgensen, J. A., Moonen-Kornips, E., Schaart, G., Havekes, B., de Vogel-van den Bosch, J., Bragt, M. C. E., Meijer, K., Schrauwen, P., Hoeks, J.

“…The relationship between the age-associated decline in mitochondrial function and its effect on skeletal muscle physiology and function remain unclear. In the…”
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Management Innovation and Leadership: The Moderating Role of Organizational Size by Vaccaro, Ignacio G., Jansen, Justin J. P., Van Den Bosch, Frans A. J., Volberda, Henk W.

“…Recent research on management innovation, i.e. new managerial processes, practices, or structures that change the nature of managerial work, suggests it can be…”
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Human neutrophils switch to an activated phenotype after homing to the lung irrespective of inflammatory disease by Fortunati, E, Kazemier, K. M, Grutters, J. C, Koenderman, L, Van den Bosch, Van J. M. M

“…Summary Systemic inflammation can be investigated by changes in expression profiles of neutrophil receptors. Application of this technology for analysis of…”
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Understanding Variation in Managers' Ambidexterity: Investigating Direct and Interaction Effects of Formal Structural and Personal Coordination Mechanisms by Mom, Tom J. M, van den Bosch, Frans A. J, Volberda, Henk W

“…Previous research focuses on firm and business unit level ambidexterity. Therefore, conceptual and empirically validated understanding about ambidexterity at…”
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Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification by Kamps, Rick, Brandão, Rita D, Bosch, Bianca J van den, Paulussen, Aimee D C, Xanthoulea, Sofia, Blok, Marinus J, Romano, Andrea

“…Next-generation sequencing (NGS) technology has expanded in the last decades with significant improvements in the reliability, sequencing chemistry, pipeline…”
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Parents’ views on accepting, declining, and expanding newborn bloodspot screening by van der Pal, Sylvia M, Wins, Sophie, Klapwijk, Jasmijn E, van Dijk, Tessa, Kater-Kuipers, Adriana, van der Ploeg, Catharina P. B, Jans, Suze M. P. J, Kemp, Stephan, Verschoof-Puite, Rendelien K, van den Bosch, Lion J. M, Henneman, Lidewij

“…Introduction The goal of newborn bloodspot screening (NBS) is the early detection of treatable disorders in newborns to offer early intervention. Worldwide,…”
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Corticosteroid treatment in sarcoidosis by Grutters, J. C, van den Bosch, J. M. M

“…At present there is no curative treatment for sarcoidosis. Immunosuppressive and/or immunomodulatory drugs can, however, be used for controlling the disease…”
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The moderating role of absorptive capacity and the differential effects of acquisitions and alliances on Big Pharma firms' innovation performance by Fernald, K D S, Pennings, H P G, van den Bosch, J F, Commandeur, H R, Claassen, E

“…In the context of increased pharmaceutical innovation deficits and Big Pharma blockbusters' patent expirations, this paper examines the moderating role of…”
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Genetic variability in the IL1RN gene and the balance between interleukin (IL)‐1 receptor agonist and IL‐1β in idiopathic pulmonary fibrosis by Barlo, N. P., van Moorsel, C. H. M., Korthagen, N. M., Heron, M., Rijkers, G. T., Ruven, H. J. T., van den Bosch, J. M. M., Grutters, J. C.

“…Summary Idiopathic pulmonary fibrosis (IPF) is a rapidly progressive interstitial lung disease of unknown aetiology. Interleukin (IL)‐1β plays an important…”
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Bronchoalveolar lavage cell pattern from healthy human lung by Heron, M., Grutters, J. C., ten Dam‐Molenkamp, K. M., Hijdra, D., van Heugten‐Roeling, A., Claessen, A. M. E., Ruven, H. J. T., van den Bosch, J. M. M., van Velzen‐Blad, H.

“…Summary Bronchoalveolar lavage (BAL) is widely accepted as a key diagnostic procedure in interstitial lung diseases (ILD). We performed a study to obtain…”
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Overall intact cognitive function in male X-linked adrenoleukodystrophy adults with normal MRI by Buermans, Noortje J M L, van den Bosch, Sharon J G, Huffnagel, Irene C, Steenweg, Marjan E, Engelen, Marc, Oostrom, Kim J, Geurtsen, Gert J

“…Men with the hereditary peroxisomal disorder X-linked adrenoleukodystrophy (ALD) are at risk of developing inflammatory demyelinating lesions in the brain. In…”
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Investigating Managers' Exploration and Exploitation Activities: The Influence of Top-Down, Bottom-Up, and Horizontal Knowledge Inflows by Mom, Tom J. M., Van Den Bosch, Frans A. J., Volberda, Henk W.

“…This paper develops and tests hypotheses on the influence of managers' knowledge inflows on managers' exploration and exploitation activities. Based on a…”
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Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants by Vago, Juliana P, Valdrighi, Natália, Blaney-Davidson, Esmeralda N, Hornikx, Daniel L A H, Neefjes, Margot, Barba-Sarasua, María E, Thielen, Nathalie G M, van den Bosch, Martijn H J, van der Kraan, Peter M, Koenders, Marije I, Amaral, Flávio A, van de Loo, Fons A J

“…Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in…”
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Implications of Tioguanine Dosing in IBD Patients with a TPMT Deficiency by Deben, Debbie S, Derijks, Luc J. J, van den Bosch, Bianca J. C, Creemers, Rob H, van Nunen, Annick, van Bodegraven, Adriaan A, Wong, Dennis R

“…Tioguanine is metabolised by fewer enzymatic steps compared to azathioprine and mercaptopurine, without generating 6-methylmercaptopurine ribonucleotides…”
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Statin treatment and reduced risk of pneumonia in patients with diabetes by van de Garde, E M W, Hak, E, Souverein, P C, Hoes, A W, van den Bosch, J M M, Leufkens, H G M

“…Background: Recent prognostic studies have shown that previous treatment with statins is associated with a better outcome in patients admitted to hospital with…”
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Structural Differentiation and Ambidexterity: The Mediating Role of Integration Mechanisms by Jansen, Justin J. P, Tempelaar, Michiel P, van den Bosch, Frans A. J, Volberda, Henk W

“…Prior studies have emphasized that structural attributes are crucial to simultaneously pursuing exploration and exploitation, yet our understanding of…”
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S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis by Cremers, Niels A. J., van den Bosch, Martijn H. J., van Dalen, Stephanie, Di Ceglie, Irene, Ascone, Giuliana, van de Loo, Fons, Koenders, Marije, van der Kraan, Peter, Sloetjes, Annet, Vogl, Thomas, Roth, Johannes, Geven, Edwin J. W., Blom, Arjen B., van Lent, Peter L. E. M.

“…Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets…”
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Neuroimaging of the bilingual brain: Structural brain correlates of listening and speaking in a second language by Kuhl, Patricia K., Stevenson, Jeff, Corrigan, Neva M., van den Bosch, Jasper J.F., Can, Dilara Deniz, Richards, Todd

“…White matter regions most affected by immersive second language experience. [Display omitted] •Second-language (L2) immersive learning induces neuroplasticity…”
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Rituximab in life threatening antisynthetase syndrome by Vandenbroucke, E., Grutters, J. C., Altenburg, J., Boersma, W. G., ter Borg, E. J., van den Bosch, J. M. M.

“…This case study reports a patient with severe interstitial pneumonitis, mild polyarthritis and polymyositis, accompanied by the presence of anti-Jo-1…”
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