Search Results - "Bos, Gert W."

Hydrolytic degradation of oligo(lactic acid): a kinetic and mechanistic study by van Nostrum, Cornelus F., Veldhuis, Theo F.J., Bos, Gert W., Hennink, Wim E.

“…This study shows that the degradation mechanism and kinetics of monodisperse oligo(lactic acid)s esterified with N-(2-hydroxypropyl)methacrylamide (HPMAm) are…”
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Sterilization of poly(dimethylamino) ethyl methacrylate-based gene transfer complexes by Bos, Gert W, Trullas-Jimeno, Ana, Jiskoot, Wim, Crommelin, Daan J.A, Hennink, Wim E

“…Parental administration of polyplex formulations for gene therapy or genetic vaccination requires sterile preparations. The possibilities and limitations of…”
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Tissue reactions of in situ formed dextran hydrogels crosslinked by stereocomplex formation after subcutaneous implantation in rats by Bos, Gert W., Hennink, Wim E., Brouwer, Linda A., den Otter, Wim, Veldhuis, Theo F.J., van Nostrum, Cornelus F., van Luyn, Marja J.A.

“…In this study, the in vivo biocompatibility of physically crosslinked dextran hydrogels was investigated. These hydrogels were obtained by mixing aqueous…”
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In situ crosslinked biodegradable hydrogels loaded with IL-2 are effective tools for local IL-2 therapy by Bos, Gert W, Jacobs, John J.L, Koten, Jan Willem, Van Tomme, Sophie, Veldhuis, Theo, van Nostrum, Cornelus F, Den Otter, Willem, Hennink, Wim E

“…We investigated the therapeutic efficacy of recombinant human interleukin-2 (rhIL-2)-loaded, in situ gelling, physically crosslinked dextran hydrogels, locally…”
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Cationic polymers that enhance the performance of HbsAg DNA in vivo by Bos, Gert W., Kanellos, Theofanis, Crommelin, Daan J.A., Hennink, Wim E., Howard, Colin R.

“…In this paper, different cationic polymers were investigated as a DNA delivery system both in vitro in dendritic and muscle cells and in vivo, in a murine…”
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Tuning the Degradation Rate of Poly(2-hydroxypropyl methacrylamide)-graft-oligo(lactic acid) Stereocomplex Hydrogels by VAN NOSTRUM, Cornelus F., VELDHUIS, Theo F. J., BOS, Gert W., HENNINK, Wim E.

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Tuning the Degradation Rate of Poly(2-hydroxypropyl methacrylamide)-g raft-oligo(lactic acid) Stereocomplex Hydrogels by van Nostrum, Cornelus F, Veldhuis, Theo F. J, Bos, Gert W, Hennink, Wim E

“…The degradation time of stereocomplex hydrogels based on poly(2-hydroxypropyl methacrylamide) (pHPMAm) with oligo(lactic acid) side chains of opposite…”
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Endothelialization of crosslinked albumin-heparin gels by Bos, G W, Scharenborg, N M, Poot, A A, Engbers, G H, Beugeling, T, van Aken, W G, Feijen, J

“…Crosslinked gels of albumin as well as heparinized albumin gels, potential sealants of prosthetic vascular grafts, were studied with regard to in vitro…”
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Adherence and proliferation of endothelial cells on surface-immobilized albumin-heparin conjugate by Bos, G W, Scharenborg, N M, Poot, A A, Engbers, G H, Terlingen, J G, Beugeling, T, Van Aken, W G, Feijen, J

“…Small-diameter vascular grafts rapidly fail after implantation, due to occlusion caused by thrombosis. This problem cannot be overcome using medication. A…”
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Proliferation of endothelial cells on surface-immobilized albumin-heparin conjugate loaded with basic fibroblast growth factor by Bos, Gert W., Scharenborg, Nicole M., Poot, André A., Engbers, Gerard H. M., Beugeling, Tom, van Aken, Willem G., Feijen, Jan

“…Seeding of endothelial cells (ECs) on the luminal surface of small‐diameter vascular grafts is a promising method to avoid occlusion of these prostheses…”
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Blood compatibility of surfaces with immobilized albumin-heparin conjugate and effect of endothelial cell seeding on platelet adhesion by Bos, Gert W., Scharenborg, Nicole M., Poot, André A., Engbers, Gerard H. M., Beugeling, Tom, van Aken, Willem G., Feijen, Jan

“…Endothelial cell (EC) seeding significantly improves the blood compatibility of artificial surfaces. Although a coating consisting of albumin and heparin…”
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