Search Results - "Bortolotto, Doriane"
-
1
NADPH Oxidase-1 Plays a Key Role in Keratinocyte Responses to UV Radiation and UVB-Induced Skin Carcinogenesis
Published in Journal of investigative dermatology (01-06-2017)“…The nicotinamide adenine dinucleotide phosphate oxidase (NOX) family enzymes are involved in several physiological functions. However, their roles in…”
Get full text
Journal Article -
2
IDO Targeting in Sarcoma: Biological and Clinical Implications
Published in Frontiers in immunology (05-03-2020)“…Sarcomas are heterogeneous malignant mesenchymal neoplasms with limited sensitivity to immunotherapy. We recently demonstrated an increase in Kynurenine…”
Get full text
Journal Article -
3
Abstract 3938: Anti-angiogenic therapy combination with hypoxia-regulating agent leads to improved tumor regression in a murine model or renal carcinoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: While antiangiogenic therapies have been shown effective in preclinical and clinical trials, tumors can acquire resistance conferring them…”
Get full text
Journal Article -
4
Abstract 6658: Deciphering anti-PDL1 effect in a syngeneic mouse model of sarcoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: In the context of novel immuno-oncology therapeutics development at preclinical stage, it's crucial to understand the primary features of…”
Get full text
Journal Article -
5
Abstract 622: Development and characterization of a novel anti-PD1 resistant sarcoma mouse model
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Soft Tissue Sarcoma (STS) is known to be resistant to cancer immunotherapy including the prototypical immune checkpoint inhibitor (ICI)…”
Get full text
Journal Article -
6
UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis
Published in Oncogenesis (New York, NY) (24-09-2019)“…The leading cause of cutaneous squamous cell carcinomas (cSCCs) is exposure to ultraviolet radiation (UV). Unlike most other cancers, the incidence rates of…”
Get full text
Journal Article