Search Results - "Bortner, Donna"

Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism by Stumpo, Deborah J, Trempus, Carol S, Tucker, Charles J, Huang, Weichun, Li, Leping, Kluckman, Kimberly, Bortner, Donna M, Blackshear, Perry J

“…The ZFP36L3 protein is a rodent-specific, placenta- and yolk sac-specific member of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins. These…”
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Efficient division and sampling of cell colonies using microcup arrays by Pai, Jeng-Hao, Kluckman, Kimberly, Cowley, Dale O, Bortner, Donna M, Sims, Christopher E, Allbritton, Nancy L

“…A microengineered array to sample clonal colonies is described. The cells were cultured on an array of individually releasable elements until the colonies…”
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Switching of Melanocyte Pigmentation Associated with Pituitary Pars Intermedia Tumors in Rb+/- and p27-/- Female Mice with Yellow Pelage by Smith, Adrian P. L., Henze, Martha, Osborn, Kent G., Lee, John A., Bortner, Donna M., Rosenberg, Michael P., Reed, Steven I.

“…As an incidental finding in a study of mammary tumorigenesis, two lines of genetically engineered mice were observed to develop pigmentation changes of the…”
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Systemically delivered antisense oligomers upregulate gene expression in mouse tissues by Kole, Ryszard, Sazani, Peter, Gemignani, Federica, Kang, Shin-Hong, Maier, Martin A, Manoharan, Muthiah, Persmark, Magnus, Bortner, Donna

“…Systemically injected 2'-O-methoxyethyl (2'-O-MOE)-phosphorothioate and PNA-4K oligomers (peptide nucleic acid with four lysines linked at the C terminus)…”
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Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E by Bortner, Donna M., Rosenberg, Michael P.

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Transient forebrain over-expression of CRF induces plasma corticosterone and mild behavioural changes in adult conditional CRF transgenic mice by Vicentini, Elena, Arban, Roberto, Angelici, Ornella, Maraia, Gabriella, Perico, MariaElisa, Mugnaini, Manolo, Ugolini, Annarosa, Large, Charles, Domenici, Enrico, Gerrard, Philip, Bortner, Donna, Mansuy, Isabelle M., Mangiarini, Laura, Merlo-Pich, Emilio

“…Converging findings support a role for extra-hypothalamic CRF in the mediation of the stress response. The influence of CRF in the amygdala is well…”
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DNA synthesis and production of interleukin 1 by lymph node macrophages in culture by Mastro, A M, Bortner, D M, Pishak, S A

“…When bovine lymph node cells are cultured for several days the adherent macrophage population increases by as much as tenfold. This increase in cell number is…”
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Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants by Kucera, G T, Bortner, D M, Rosenberg, M P

“…The classical mouse fancy Agouti gene is responsible for the wild-type coat color where hairs are banded black and yellow. The Agouti gene encodes a…”
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Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression by LANGER, S. J, BORTNER, D. M, ROUSSEL, M. F, SHERR, C. J, OSTROWSKI, M. C

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Why transgenic and knockout animal models should be used (for drug efficacy studies in cancer) by Rosenberg, M P, Bortner, D

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Overexpression of anAgouticDNA in the Skin of Transgenic Mice Recapitulates Dominant Coat Color Phenotypes of Spontaneous Mutants by Kucera, Gary T., Bortner, Donna M., Rosenberg, Michael P.

“…The classical mouse fancyAgoutigene is responsible for the wild-type coat color where hairs are banded black and yellow. TheAgoutigene encodes a 131-amino-acid…”
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The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor by BORTNER, D. M, ULIVI, M, ROUSSEL, M. F, OSTROWSKI, M. C

“…To determine whether ras p21 products are necessary for signal transduction mediated by the colony stimulating factor-1 receptor (CSF-1R, the c-fms…”
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ras oncogene activation of a VL30 transcriptional element is linked to transformation by OWEN, R. D, BORTNER, D. M, OSTROWSKI, M. C

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Analysis ofras signaling pathways involved in regulating gene expression and transformation by Bortner, Donna Marie

“…Tumorigenesis occurs by a multi-step process which is postulated to involve both the activation of oncogenes and the inactivation of tumor suppressor genes…”
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Analysis of the v-myb structural components important for transactivation of gene expression by BORTNER, D. M, OSTROWSKI, M. C

“…In order to define the domains of the v-myb protein that are important for transactivation of gene expression, we have studied transactivation by the v-myb…”
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Changes in the restriction endonuclease patterns of four modified-live infectious bovine rhinotracheitis virus (IBRV) vaccines after one passage in host animal by Whetstone, C, Miller, J, Bortner, D, Van der Maaten, M

“…Four genomically different bovine herpes virus 1 (BHV 1) vaccines were used to inoculate BHV 1-negative heifers. Restriction endonuclease analysis (REA) of…”
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ras Oncogene Activation of a VL30 Transcriptional Element Is Linked to Transformation by Owen, Russell D., Bortner, Donna M., Ostrowski, Michael C.

“…The activity of a murine VL30 transcriptional element was increased 20-fold in transient assays by coexpression of mutant ras genes. The cis element did not…”
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Mitogenic Signaling By Colony-Stimulating Factor 1 and ras Is Suppressed by the ets-2 DNA-Binding Domain and Restored by myc Overexpression by Langer, Stephen J., Bortner, Donna M., Roussel, Martine F., Sherr, Charles J., Ostrowski, Michael C.

“…The activity of p21 ras is required for the proliferative response to colony-stimulating factor 1 (CSF-1), and signals transduced by both the CSF-1 receptor…”
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Overproduction of MDM2 in vivo disrupts S phase independent of E2F1 by REINKE, V, BORTNER, D. M, AMELSE, L. L, LUNDGREN, K, ROSENBERG, M. P, FINLAY, C. A, LOZANO, G

“…Expression of a beta-lactoglobulin (BLG)/mdm2 transgene (BLGmdm2) in the epithelial cells of the mouse mammary gland causes an uncoupling of S phase from M…”
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