Search Results - "Borth, Wolfgang"

Plasminogen-mediated matrix invasion and degradation by macrophages is dependent on surface expression of annexin II by Falcone, Domenick J., Borth, Wolfgang, Khan, K.M. Faisal, Hajjar, Katherine A.

“…Genetic evidence demonstrates the importance of plasminogen activation in the migration of macrophages to sites of injury and inflammation, their removal of…”
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Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia by McCaffrey, T A, Falcone, D J, Borth, W, Brayton, C F, Weksler, B B

“…We previously reported that heparin inhibits the proliferation of fibroblasts and vascular smooth muscle cells (SMC), in part, by binding to and increasing the…”
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Alpha 2-macroglobulin. A multifunctional binding and targeting protein with possible roles in immunity and autoimmunity by Borth, W

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Degradation of Amyloid β-Protein by a Serine Protease-α2-Macroglobulin Complex by Qiu, Wei Qiao, Borth, Wolfgang, Ye, Zhen, Haass, Christian, Teplow, David B., Selkoe, Dennis J.

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Homocysteine and Other Sulfhydryl Compounds Enhance the Binding of Lipoprotein(a) to Fibrin: A Potential Biochemical Link between Thrombosis, Atherogenesis, and Sulfhydryl Compound Metabolism by Harpel, Peter C., Chang, Victor T., Borth, Wolfgang

“…We have previously shown that lipoprotein(a) [Lp(a)], an atherogenic lipoprotein that contains apolipoprotein(a), which shares partial structural homology to…”
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Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics by Borth, W

“…Alpha 2-macroglobulin (alpha 2M) and related proteins share the function of binding host or foreign peptides and particles, thereby serving as humoral defense…”
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Lipoprotein(a), plasmin modulation, and atherogenesis by Harpel, P C, Hermann, A, Zhang, X, Ostfeld, I, Borth, W

“…Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein however the mechanisms by which Lp(a) promote the atherosclerotic process are not clear. The…”
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Transglutaminases catalyze cross-linking of plasminogen to fibronectin and human endothelial cells by Bendixen, E, Borth, W, Harpel, P C

“…We have previously reported that apolipoprotein (a) is a substrate for transglutaminases. We now demonstrate that plasminogen which is homologous to…”
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Degradation of Amyloid -Protein by a Serine Protease--Macroglobulin Complex by Wei Qiao Qiu, Wolfgang Borth, Zhen Ye, Christian Haass, David B. Teplow, Dennis J. Selkoe

“…Progressive cerebral deposition of the amyloid β-peptide (Aβ) is an early and constant feature of Alzheimer's disease. Aβ is derived by proteolysis from the…”
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Role of Alpha2-macroglobulin in joint inflammation: humoral and cellular aspects by Borth, Wolfgang

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Identification of mechanisms that may modulate the role of lipoprotein(a) in thrombosis and atherogenesis by Harpel, P C, Borth, W

“…In this report, we review recent findings concerning the identification of mechanisms that may modulate the role of lipoprotein(a), or Lp(a), in thrombosis and…”
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Homocysteine and other sulfhydryl compounds enhance the binding of lipoproteins(a) to fibrin: A potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism by Harpel, Peter C, Chang, Victor T, Borth, Wolfgang

“…A study reports that honocystein, at concentrations as low as 8 meanM, significantly increases the affinity of lipoprotein(a) for fibrin. This finding and its…”
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Lipoprotein (a) is a substrate for factor XIIIa and tissue transglutaminase by BORTH, W, CHANG, V, BISHOP, P, HARPEL, P. C

“…The mechanisms which mediate deposition of lipoprotein (a) (Lp(a)), an atherogenic lipoprotein particle, onto the vessel wall and cell surfaces are unknown. An…”
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Binding of IL-1 beta to alpha-macroglobulins and release by thioredoxin by Borth, W, Scheer, B, Urbansky, A, Luger, TA, Sottrup-Jensen, L

“…Human alpha 2-macroglobulin (H alpha 2M) is a major IL-1 beta binding plasma protein. The characteristics of the H alpha 2M IL-1 beta complex formation…”
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Fibrin, lipoprotein(a), plasmin interactions: a model linking thrombosis and atherogenesis by Harpel, P C, Borth, W

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Binding of Recombinant Interleukin-1β to the Third Complement Component and α2-Macroglobulin After Activation of Serum by Immune Complexes by Borth, Wolfgang, Urbanski, Agatha, Prohaska, Rainer, Susani, Martin, Luger, Thomas A.

“…Activation of human normal serum with tetanus/anti-tetanus immune complexes (TAT-IC) resulted in increased binding of 125l-labeled interleukin-1β (IL-1β) to…”
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Regulation of macrophage receptor-bound plasmin by autoproteolysis by Falcone, D J, Borth, W, McCaffrey, T A, Mathew, J, McAdam, K

“…The activation of plasminogen by macrophage is regulated by their expression of receptors for urokinase and plasmin(ogen). In these studies we have examined…”
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Interleukin-6 is produced by epidermal cells and plays an important role in the activation of human T-lymphocytes and natural killer cells by Luger, T A, Schwarz, T, Krutmann, J, Kirnbauer, R, Neuner, P, Köck, A, Urbanski, A, Borth, W, Schauer, E

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alpha 2-Macroglobulin in joint disease by Borth, W, Dunky, A, Viehberger, G

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Influence of plasma fibronectin on collagen cleavage by collagenase by Menzel, J, Borth, W

“…The influence of plasma fibronectin on the cleavage of interstitial collagen types I, II, and III by mammalian collagenase was investigated. To this end,…”
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