Search Results - "Borsos, Barbara N."

The role of p53 in the DNA damage-related ubiquitylation of S2P RNAPII by Borsos, Barbara N, Pantazi, Vasiliki, Páhi, Zoltán G, Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Berzsenyi, Ivett, Pankotai, Tibor

“…DNA double-strand breaks are one of the most deleterious lesions for the cells, therefore understanding the macromolecular interactions of the DNA…”
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Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster by Páhi, Zoltán G., Kovács, Levente, Szűcs, Diána, Borsos, Barbara N., Deák, Péter, Pankotai, Tibor

“…Ubiquitylation is critical for preventing aberrant DNA repair and for efficient maintenance of genome stability. As deubiquitylases (DUBs) counteract…”
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SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response by Majoros, Hajnalka, Borsos, Barbara N., Ujfaludi, Zsuzsanna, Páhi, Zoltán G., Mórocz, Mónika, Haracska, Lajos, Boros, Imre Miklós, Pankotai, Tibor

“…UV-induced DNA damage response and repair are extensively studied processes, as any malfunction in these pathways contributes to the activation of…”
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Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure by Nagy-Mikó, Bence, Németh-Szatmári, Orsolya, Faragó-Mészáros, Réka, Csókási, Aliz, Bognár, Bence, Ördög, Nóra, Borsos, Barbara N., Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Oláh-Németh, Orsolya, Nikolényi, Aliz, Dobi, Ágnes, Kószó, Renáta, Sántha, Dóra, Lázár, György, Simonka, Zsolt, Paszt, Attila, Ormándi, Katalin, Pankotai, Tibor, Boros, Imre M., Villányi, Zoltán, Vörös, András

“…We aimed to investigate the contribution of co-translational protein aggregation to the chemotherapy resistance of tumor cells. Increased co-translational…”
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Emerging Roles of Post-Translational Modifications in Nucleotide Excision Repair by Borsos, Barbara N, Majoros, Hajnalka, Pankotai, Tibor

“…Nucleotide excision repair (NER) is a versatile DNA repair pathway which can be activated in response to a broad spectrum of UV-induced DNA damage, such as…”
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The clinical significance of epigenetic and RNAPII variabilities occurring in clear cell renal cell carcinoma as a potential prognostic marker by Ördög, Nóra, Borsos, Barbara N, Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Pankotai-Bodó, Gabriella, Bankó, Sarolta, Sükösd, Farkas, Kuthi, Levente, Pankotai, Tibor

“…•30 ccRCC patients were used, to follow the epigenetic changes (γH2A.X, H3K4me3 and H3K9me3) and the alterations in the level of RNA polymerase II…”
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BC-miR: Monitoring Breast Cancer-Related miRNA Profile in Blood Sera—A Prosperous Approach for Tumor Detection by Borsos, Barbara N, Páhi, Zoltán G, Ujfaludi, Zsuzsanna, Sükösd, Farkas, Nikolényi, Alíz, Bankó, Sarolta, Pankotai-Bodó, Gabriella, Oláh-Németh, Orsolya, Pankotai, Tibor

“…Breast cancer is the most frequent cancer with a high fatality rate amongst women worldwide. Diagnosing at an early stage is challenging, and due to the…”
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Identifying Suitable Reference Gene Candidates for Quantification of DNA Damage-Induced Cellular Responses in Human U2OS Cell Culture System by Barta, Nikolett, Ördög, Nóra, Pantazi, Vasiliki, Berzsenyi, Ivett, Borsos, Barbara N., Majoros, Hajnalka, Páhi, Zoltán G., Ujfaludi, Zsuzsanna, Pankotai, Tibor

“…DNA repair pathways trigger robust downstream responses, making it challenging to select suitable reference genes for comparative studies. In this study, our…”
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Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis by Borsos, Barbara N., Pankotai, Tibor, Kovács, Dávid, Popescu, Christina, Páhi, Zoltán, Boros, Imre M.

“…The molting during Drosophila development is tightly regulated by the ecdysone hormone. Several steps of the ecdysone biosynthesis have been already identified…”
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dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster by Pahi, Zoltan, Kiss, Zsuzsanna, Komonyi, Orbán, Borsos, Barbara N, Tora, Laszlo, Boros, Imre M, Pankotai, Tibor

“…In eukaryotes the TFIID complex is required for preinitiation complex assembly which positions RNA polymerase II around transcription start sites. On the other…”
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Systematic overview on the most widespread techniques for inducing and visualizing the DNA double-strand breaks by Berzsenyi, Ivett, Pantazi, Vasiliki, Borsos, Barbara N., Pankotai, Tibor

“…DNA double-strand breaks (DSBs) are one of the most frequent causes of initiating cancerous malformations, therefore, to reduce the risk, cells have developed…”
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Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair by Borsos, Barbara N., Majoros, Hajnalka, Pankotai, Tibor

“…The proper function of DNA repair is indispensable for eukaryotic cells since accumulation of DNA damages leads to genome instability and is a major cause of…”
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CDKL5 kinase controls transcription‐coupled responses to DNA damage by Khanam, Taran, Muñoz, Ivan, Weiland, Florian, Carroll, Thomas, Morgan, Michael, Borsos, Barbara N, Pantazi, Vasiliki, Slean, Meghan, Novak, Miroslav, Toth, Rachel, Appleton, Paul, Pankotai, Tibor, Zhou, Houjiang, Rouse, John

“…Mutations in the gene encoding the CDKL5 kinase are among the most common genetic causes of childhood epilepsy and can also give rise to the severe…”
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PARylation During Transcription: Insights into the Fine-Tuning Mechanism and Regulation by Páhi, Zoltán G, Borsos, Barbara N, Pantazi, Vasiliki, Ujfaludi, Zsuzsanna, Pankotai, Tibor

“…Transcription is a multistep, tightly regulated process. During transcription initiation, promoter recognition and pre-initiation complex (PIC) formation take…”
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Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage by Borsos, Barbara N., Huliák, Ildikó, Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Gyenis, Ákos, Pukler, Peter, Boros, Imre M., Pankotai, Tibor

“…The p53 tumour suppressor regulates the transcription initiation of selected genes by binding to specific DNA sequences at their promoters. Here we report a…”
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The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export by Kristó, Ildikó, Bajusz, Csaba, Borsos, Barbara N., Pankotai, Tibor, Dopie, Joseph, Jankovics, Ferenc, Vartiainen, Maria K., Erdélyi, Miklós, Vilmos, Péter

“…Current models imply that the evolutionarily conserved, actin-binding Ezrin-Radixin-Moesin (ERM) proteins perform their activities at the plasma membrane by…”
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Novel biomarkers of mitochondrial dysfunction in Long COVID patients by Szögi, Titanilla, Borsos, Barbara N., Masic, Dejana, Radics, Bence, Bella, Zsolt, Bánfi, Andrea, Ördög, Nóra, Zsiros, Csenge, Kiricsi, Ágnes, Pankotai-Bodó, Gabriella, Kovács, Ágnes, Paróczai, Dóra, Botkáné, Andrea Lugosi, Kajtár, Béla, Sükösd, Farkas, Lehoczki, Andrea, Polgár, Tamás, Letoha, Annamária, Pankotai, Tibor, Tiszlavicz, László

“…Coronavirus disease 2019 (COVID-19) can lead to severe acute respiratory syndrome, and while most individuals recover within weeks, approximately 30–40%…”
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Predictive Potential of RNA Polymerase B Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure by Nagy-Mikó, Bence, Németh-Szatmári, Orsolya, Faragó-Mészáros, Réka, Csókási, Aliz, Bognár, Bence, Ördög, Nóra, Borsos, Barbara N, Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Oláh-Németh, Orsolya, Nikolényi, Aliz, Dobi, Ágnes, Kószó, Renáta, Sántha, Dóra, Lázár, György, Simonka, Zsolt, Paszt, Attila, Ormándi, Katalin, Pankotai, Tibor, Boros, Imre M, Villányi, Zoltán, Vörös, András

“…We aimed to investigate the contribution of co-translational protein aggregation to the chemotherapy resistance of tumor cells. Increased co-translational…”
Get full text

dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster: e0142226 by Pahi, Zoltan, Kiss, Zsuzsanna, Komonyi, Orban, Borsos, Barbara N, Tora, Laszlo, Boros, Imre M, Pankotai, Tibor

“…In eukaryotes the TFIID complex is required for preinitiation complex assembly which positions RNA polymerase II around transcription start sites. On the other…”
Get full text