Search Results - "Borroni, Elena Monica"

Cancer Immunoediting and beyond in 2021 by Borroni, Elena Monica, Grizzi, Fabio

“…Human cancer has been depicted as a non-linear dynamic system that is discontinuous in space and time, but progresses through different sequential states…”
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Aberrant CXCR4 Signaling at Crossroad of WHIM Syndrome and Waldenstrom's Macroglobulinemia by Milanesi, Samantha, Locati, Massimo, Borroni, Elena Monica

“…Given its pleiotropic functions, including its prominent role in inflammation, immune responses and cancer, the C-X-C chemokine receptor type 4 (CXCR4) has…”
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Differential Effects of Posttranslational Modifications of CXCL8/Interleukin-8 on CXCR1 and CXCR2 Internalization and Signaling Properties by Vacchini, Alessandro, Mortier, Anneleen, Proost, Paul, Locati, Massimo, Metzemaekers, Mieke, Borroni, Elena Monica

“…CXCL8 or interleukin (IL)-8 directs neutrophil migration and activation through interaction with CXCR1 and CXCR2 that belong to the family of G protein-coupled…”
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Exploring the CXCR4/CXCR7/CXCL12 Axis in Primary Desmoid Tumors by Baccalini, Edoardo Andrea, Renne, Salvatore Lorenzo, Colombo, Piergiuseppe, Pasqualini, Fabio, Quagliuolo, Vittorio Lorenzo, Cananzi, Ferdinando Carlo Maria, Grizzi, Fabio, Borroni, Elena Monica

“…Desmoid tumors have an extremely variable natural history. The uncertainty behind desmoid behavior reflects the complexity, which subtends its development and…”
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Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions by Martano, Giuseppe, Borroni, Elena Monica, Lopci, Egesta, Cattaneo, Maria Grazia, Mattioli, Milena, Bachi, Angela, Decimo, Ilaria, Bifari, Francesco

“…Stem cells can stay quiescent for a long period of time or proliferate and differentiate into multiple lineages. The activity of stage-specific metabolic…”
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New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM by Scala, Stefania, D'Alterio, Crescenzo, Milanesi, Samantha, Castagna, Alessandra, Carriero, Roberta, Farina, Floriana Maria, Locati, Massimo, Borroni, Elena Monica

“…Deciphering the molecular alterations leading to disease initiation and progression is currently crucial to identify the most relevant targets for precision…”
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Control of Cytoskeletal Dynamics by β-Arrestin1/Myosin Vb Signaling Regulates Endosomal Sorting and Scavenging Activity of the Atypical Chemokine Receptor ACKR2 by Vacchini, Alessandro, Cancellieri, Cinzia, Milanesi, Samantha, Badanai, Sabrina, Savino, Benedetta, Bifari, Francesco, Locati, Massimo, Bonecchi, Raffaella, Borroni, Elena Monica

“…The atypical chemokine receptor ACKR2, formerly named D6, is a scavenger chemokine receptor with a non-redundant role in the control of inflammation and…”
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Recognition Versus Adaptive Up-regulation and Degradation of CC Chemokines by the Chemokine Decoy Receptor D6 Are Determined by Their N-terminal Sequence by Savino, Benedetta, Borroni, Elena Monica, Torres, Nina Machado, Proost, Paul, Struyf, Sofie, Mortier, Anneleen, Mantovani, Alberto, Locati, Massimo, Bonecchi, Raffaella

“…The chemokine decoy receptor D6 controls inflammatory responses by selective recognition and degradation of most CCR1 to CCR5 agonistic ligands. CCL14 is a…”
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Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties by Vacchini, Alessandro, Maffioli, Elisa, Di Silvestre, Dario, Cancellieri, Cinzia, Milanesi, Samantha, Nonnis, Simona, Badanai, Sabrina, Mauri, Pierluigi, Negri, Armando, Locati, Massimo, Tedeschi, Gabriella, Borroni, Elena Monica

“…ACKR2 is an atypical chemokine receptor which is structurally uncoupled from G proteins and is unable to activate signaling pathways used by conventional…”
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Flow cytometry applications for the analysis of chemokine receptor expression and function by Anselmo, Achille, Mazzon, Cristina, Borroni, Elena Monica, Bonecchi, Raffaella, Graham, Gerard J., Locati, Massimo

“…Chemokine receptors play an important role in leukocyte migration, both in physiological and pathological conditions, and the interest in new methodologies for…”
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Pituitary Adenoma and the Chemokine Network: A Systemic View by Grizzi, Fabio, Borroni, Elena Monica, Vacchini, Alessandro, Qehajaj, Dorina, Liguori, Manuela, Stifter, Sanja, Chiriva-Internati, Maurizio, Di Ieva, Antonio

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Shaping the gradient by nonchemotactic chemokine receptors by Borroni, Elena Monica, Bonecchi, Raffaella

“…Chemokines are a class of inflammatory mediators which main function is to direct leukocyte migration through the binding to G protein-coupled receptors…”
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Overview and potential unifying themes of the atypical chemokine receptor family by Vacchini, Alessandro, Locati, Massimo, Borroni, Elena Monica

“…Review of ACKR biochemical and immunological properties to identify unifying themes in this emerging family. Chemokines modulate immune responses through their…”
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Chemokines sound the alarmin: The role of atypical chemokine in inflammation and cancer by Borroni, Elena Monica, Savino, Benedetta, Bonecchi, Raffaella, Locati, Massimo

“…•During inflammatory reactions, chemokines are tissue-derived signals serving as alarmins in case ot tissue damage.•Atypical chemokine receptors control…”
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Chemokines and chemokine receptors: an overview by Bonecchi, Raffaella, Galliera, Emanuela, Borroni, Elena Monica, Corsi, Massimiliano Marco, Locati, Massimo, Mantovani, Alberto

“…Chemokines are chemotactic cytokines orchestrating leukocyte recruitment in physiological and pathological conditions. This complex system includes 42…”
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Corrigendum to “Chemokines sound the alarmin: The role of atypical chemokine receptors in inflammation and cancer” [Semin. Immunol. 38 (2018) 63–71] by Borroni, Elena Monica, Savino, Benedetta, Bonecchi, Raffaella, Locati, Massimo

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Inflammation and prostate cancer: friends or foe? by Taverna, Gianluigi, Pedretti, Elisa, Di Caro, Giuseppe, Borroni, Elena Monica, Marchesi, Federica, Grizzi, Fabio

“…Introduction Prostate cancer is the most common non-cutaneous malignancy diagnosed in men. Moving from histological observations since a long time, it has been…”
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Evolving notions on immune response in colorectal cancer and their implications for biomarker development by Grizzi, Fabio, Basso, Gianluca, Borroni, Elena Monica, Cavalleri, Tommaso, Bianchi, Paolo, Stifter, Sanja, Chiriva-Internati, Maurizio, Malesci, Alberto, Laghi, Luigi

“…Introduction Colorectal cancer (CRC) still represents the third most commonly diagnosed type of cancer in men and women worldwide. CRC is acknowledged as a…”
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Analysis of G Protein and β-Arrestin Activation in Chemokine Receptors Signaling by Vacchini, Alessandro, Busnelli, Marta, Chini, Bice, Locati, Massimo, Borroni, Elena Monica

“…Chemokines are key regulators of leukocyte migration and play fundamental roles in immune responses. The chemokine system includes a set of over 40 ligands…”
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Proteomic profile of maternal-aged blastocoel fluid suggests a novel role for ubiquitin system in blastocyst quality by Tedeschi, Gabriella, Albani, Elena, Borroni, Elena Monica, Parini, Valentina, Brucculeri, Anna Maria, Maffioli, Elisa, Negri, Armando, Nonnis, Simona, Maccarrone, Mauro, Levi-Setti, Paolo Emanuele

“…Purpose The etiology of maternal aging, a common cause of female factor infertility and a rate-limiting step in vitro fertilization (IVF) success, remains…”
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