Search Results - "Borriello, F"

T follicular helper (Tfh) cells in normal immune responses and in allergic disorders by Varricchi, G., Harker, J., Borriello, F., Marone, G., Durham, S. R., Shamji, M. H.

“…Follicular helper T cells (Tfh) are located within germinal centers of lymph nodes. Cognate interaction between Tfh, B cells, and IL‐21 drives B cells to…”
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White cell and platelet content affects the release of bioactive factors in different blood-derived scaffolds by Cabaro, S., D'Esposito, V., Gasparro, R., Borriello, F., Granata, F., Mosca, G., Passaretti, F., Sammartino, J. C., Beguinot, F., Sammartino, G., Formisano, P., Riccitiello, F.

“…Platelet-derived factors are biomaterials that might accelerate healing process in oral, maxillofacial, and several other applications. Release of specific…”
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Elevated plasma levels of vascular permeability factors in C1 inhibitor‐deficient hereditary angioedema by Loffredo, S., Bova, M., Suffritti, C., Borriello, F., Zanichelli, A., Petraroli, A., Varricchi, G., Triggiani, M., Cicardi, M., Marone, G.

“…Background Hereditary angioedema with C1 inhibitor deficiency (C1‐INH‐HAE) is a rare inherited genetic disease characterized by recurrent swelling episodes of…”
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Characterization of a novel autologous pan-cancer cellular immunotherapy by Borriello, F., Keegan, J., Lederer, J.

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Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence by Borriello, F, Krauter, K S

“…The murine alpha 1-protease inhibitors (alpha 1-PI) are encoded by a small gene family on chromosome 12. Studies of alpha 1-PI and other serine protease…”
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Construction of quantitative RT-PCR MIMICs by Borriello, F, Lederer, J

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Differential expression of alternate mB7-2 transcripts by Borriello, F, Oliveros, J, Freeman, GJ, Nadler, LM, Sharpe, AH

“…The murine B7-2 (mB7-2) costimulatory molecule is expressed on APCs early during the course of an immune response, suggesting that it may play a pivotal role…”
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Evidence that multiple residues on both the alpha-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor by Ajitkumar, P, Geier, S S, Kesari, K V, Borriello, F, Nakagawa, M, Bluestone, J A, Saper, M A, Wiley, D C, Nathenson, S G

“…Single amino acid substitutions at nine different positions on the H-2Kb molecules from in vitro-mutagenized, immunologically altered, somatic cell variants…”
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Characterization of the murine B7-1 genomic locus reveals an additional exon encoding an alternative cytoplasmic domain and a chromosomal location of chromosome 16, band B5 by Borriello, F, Freeman, GJ, Edelhoff, S, Disteche, CM, Nadler, LM, Sharpe, AH

“…The murine B7-1 (mB7-1) molecule expressed on APCs delivers a costimulatory signal for T cell activation through its T cell counter-receptor CD28, resulting in…”
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Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization by Borriello, Francesco, Pietrasanta, Carlo, Lai, Jacqueline C Y, Walsh, Lois M, Sharma, Pankaj, O'Driscoll, David N, Ramirez, Juan, Brightman, Spencer, Pugni, Lorenza, Mosca, Fabio, Burkhart, David J, Dowling, David J, Levy, Ofer

“…Immunization is key to preventing infectious diseases, a leading cause of death early in life. However, due to age-specific immunity, vaccines often…”
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Intracellular transport of class I histocompatibility molecules. Influence of protein folding on transport to the cell surface by Williams, D B, Borriello, F, Zeff, R A, Nathenson, S G

“…To examine the structural requirements for the intracellular transport and surface expression of Class I histocompatibility molecules, we studied somatic cell…”
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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 by Tivol, Elizabeth A., Borriello, Frank, Schweitzer, A.Nicola, Lynch, William P., Bluestone, Jeffrey A., Sharpe, Arlene H.

“…The B7-CD28/CTLA-4 costimulatory pathway can provide a signal pivotal for T cell activation. Signaling through this pathway is complex due to the presence of…”
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B7-1 and B7-2 Have Overlapping, Critical Roles in Immunoglobulin Class Switching and Germinal Center Formation by Borriello, Frank, Sethna, Michael P, Boyd, Scott D, Schweitzer, A.Nicola, Tivol, Elizabeth A, Jacoby, Douglas, Strom, Terry B, Simpson, Elizabeth M, Freeman, Gordon J, Sharpe, Arlene H

“…Humoral immune responses were characterized in mouse strains lacking either or both B7 molecules. Mice deficient in both B7-1 and B7-2 failed to generate…”
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CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice by Tivol, EA, Boyd, SD, McKeon, S, Borriello, F, Nickerson, P, Strom, TB, Sharpe, AH

“…Mice lacking CTLA-4 develop a fatal spontaneous lymphoproliferative disease with massive lymphocytic infiltrates and tissue destruction in many organs…”
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Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells by Spada, Franca M., Borriello, Frank, Sugita, Masahiko, Watts, Gerald F. M., Koezuka, Yasuhiko, Porcelli, Steven A.

“…CD1d is a key antigen‐presenting molecule involved in the selection and activation of a highly conserved T cell subset known as NK T cells. In this study, we…”
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Group psychotherapy with acting-out patients: specific problems and technique by Borriello, J F

“…Severe crises bring acting-out patients to psychotherapy. In order to keep them in treatment, the therapist has to educate them about what psychotherapy is. An…”
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Role of costimulators in T cell differentiation: studies using antigen- presenting cells lacking expression of CD80 or CD86 by Schweitzer, AN, Borriello, F, Wong, RC, Abbas, AK, Sharpe, AH

“…For T cells to be optimally activated, recognition of Ag/MHC complexes by the TCR must be accompanied by a second, costimulatory signal that can be provided…”
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Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production by FREEMAN, G. J, BORRIELLO, F, LOMBARD, L. A, WANG, S, GRAY, G. S, NADLER, L. M, SHARPE, A. H, HODES, R. J, REISER, H, GRIBBEN, J. G, NG, J. W, KIM, J, GOLDBERG, J. M, HATHCOCK, K, LASZLO, G

“…The B7-1 molecule, expressed on antigen presenting cells (APC), provides a crucial costimulatory signal for T cell activation. Recent studies demonstrate the…”
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Patients with acting-out character disorders by Borriello, J F

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Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice by Freeman, Gordon J., Borriello, Frank, Hodes, Richard J., Reiser, Hans, Hathcock, Karen S., Laszlo, Gloria, McKnight, Andrew J., Kim, Jinny, Du, Lina, Lombard, David B., Gray, Gary S., Nadler, Lee M., Sharpe, Arlene H.

“…B7 delivers a costimulatory signal through CD28, resulting in interleukin-2 secretion and T cell proliferation. Blockade of this pathway results in T cell…”
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