Search Results - "Borreguero, Juan M"

Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio by Lorente, Leonardo, Martín, María M, Solé-Violán, Jordi, Blanquer, José, Labarta, Lorenzo, Díaz, César, Borreguero-León, Juan M, Orbe, Josune, Rodríguez, José A, Jiménez, Alejandro, Páramo, José A

“…Higher circulating levels of tissue inhibitor of matrix metalloproteinases (TIMP)-1 at the time of severe sepsis diagnosis have been reported in nonsurviving…”
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Red blood cell distribution width during the first week is associated with severity and mortality in septic patients by Lorente, Leonardo, Martín, María M, Abreu-González, Pedro, Solé-Violán, Jordi, Ferreres, José, Labarta, Lorenzo, Díaz, César, González, Oswaldo, García, Daida, Jiménez, Alejandro, Borreguero-León, Juan M

“…Higher values of red blood cell distribution width (RDW) have been found in non-surviving than in surviving septic patients. However, it is unknown whether RDW…”
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Association between serum tissue inhibitor of matrix metalloproteinase-1 levels and mortality in patients with severe brain trauma injury by Lorente, Leonardo, Martín, María M, López, Patricia, Ramos, Luis, Blanquer, José, Cáceres, Juan J, Solé-Violán, Jordi, Solera, Jorge, Cabrera, Judith, Argueso, Mónica, Ortiz, Raquel, Mora, María L, Lubillo, Santiago, Jiménez, Alejandro, Borreguero-León, Juan M, González, Agustín, Orbe, Josune, Rodríguez, José A, Páramo, José A

“…Matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) play a role in neuroinflammation after brain trauma injury (TBI)…”
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Serum levels of caspase-cleaved cytokeratin-18 in patients with severe traumatic brain injury are associated with mortality: a pilot study by Lorente, Leonardo, Martín, María M, González-Rivero, Agustín F, Argueso, Mónica, Ramos, Luis, Solé-Violán, Jordi, Cáceres, Juan J, Jiménez, Alejandro, Borreguero-León, Juan M

“…There have been found apoptotic changes in brain tissue samples from animals and humans after a traumatic brain injury (TBI). The protein cytokeratin 18…”
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Persistently high circulating tissue inhibitor of matrix metalloproteinase-1 levels in non-survivor brain trauma injury patients by Lorente, Leonardo, Martín, María M., Ramos, Luis, Argueso, Mónica, Cáceres, Juan J., Solé-Violán, Jordi, Jiménez, Alejandro, Borreguero-León, Juan M., González-Rivero, Agustín F., Orbe, Josune, Rodríguez, José A., Páramo, José A.

“…Previously, higher circulating levels of matrix metalloproteinase (MMP)-9 and tissue inhibitor matrix metalloproteinases (TIMP)-1 were reported in the first…”
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Serum caspase-3 levels and mortality are associated in patients with severe traumatic brain injury by Lorente, Leonardo, Martín, María M, Argueso, Mónica, Ramos, Luis, Solé-Violán, Jordi, Riaño-Ruiz, Marta, Jiménez, Alejandro, Borreguero-León, Juan M

“…Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in…”
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The 4G/4G Genotype of PAI-1 Polymorphism Is Associated with Higher Plasma PAI-1 Concentrations and Mortality in Patients with Severe Sepsis by Lorente, Leonardo, Martín, María M, Borreguero-León, Juan M, Barrios, Ysamar, Solé-Violán, Jordi, Ferreres, José, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro

“…Two studies have reported that patients with the 4G/4G genotype of the plasminogen activator inhibitor-1 (PAI-1) genetic polymorphism had higher plasma PAI-1…”
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High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients by Lorente, Leonardo, Martín, María M, Ramos, Luis, Argueso, Mónica, Cáceres, Juan J, Solé-Violán, Jordi, Jiménez, Alejandro, Borreguero-León, Juan M, González-Rivero, Agustín F, Orbe, Josune, Rodríguez, José A, Páramo, José A

“…Higher circulating levels of tissue inhibitor of matrix metalloproteinases (TIMP)-1 early after ischemic stroke have been associated with lower survival. The…”
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Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis by Lorente, Leonardo, Martín, María M, Labarta, Lorenzo, Díaz, César, Solé-Violán, Jordi, Blanquer, José, Orbe, Josune, Rodríguez, José A, Jiménez, Alejandro, Borreguero-León, Juan M, Belmonte, Felipe, Medina, Juan C, Llimiñana, Maria C, Ferrer-Agüero, José M, Ferreres, José, Mora, María L, Lubillo, Santiago, Sánchez, Manuel, Barrios, Ysamar, Sierra, Antonio, Páramo, José A

“…Matrix metalloproteinases (MMPs) play a role in infectious diseases through extracellular matrix (ECM) degradation, which favors the migration of immune cells…”
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Association between Serum Soluble CD154 Levels and Mortality in Patients with Malignant Middle Cerebral Artery Infarction by Lorente, Leonardo, Martín, María M, González-Rivero, Agustín F, Ramos, Luis, Argueso, Mónica, Cáceres, Juan J, Solé-Violán, Jordi, Jiménez, Alejandro, Borreguero-León, Juan M

“…CD154 and its soluble counterpart (sCD154) are proteins of the tumor necrosis factor (TNF) family and exhibit proinflamatory and procoagulant properties…”
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Safety and effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial by Jiménez, Juan J, Iribarren, José L, Brouard, Maitane, Hernández, Domingo, Palmero, Salomé, Jiménez, Alejandro, Lorente, Leonardo, Machado, Patricia, Borreguero, Juan M, Raya, José M, Martín, Beatriz, Pérez, Rosalía, Martínez, Rafael, Mora, María L

“…In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional…”
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Serum tissue inhibitor of matrix metalloproteinase-1 levels are associated with mortality in patients with malignant middle cerebral artery infarction by Lorente, Leonardo, Martín, María M, Ramos, Luis, Cáceres, Juan J, Solé-Violán, Jordi, Argueso, Mónica, Jiménez, Alejandro, Borreguero-León, Juan M, Orbe, Josune, Rodríguez, José A, Páramo, José A

“…In the last years, circulating matrix metalloproteinases (MMP)-9 levels have been associated with functional outcome in ischemic stroke patients. However the…”
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Serum levels of caspase-cleaved cytokeratin-18 and mortality are associated in severe septic patients: pilot study by Lorente, Leonardo, Martín, María M, González-Rivero, Agustín F, Ferreres, José, Solé-Violán, Jordi, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro, Borreguero-León, Juan M

“…Apoptosis is increased in sepsis. Cytokeratin 18 (CK-18), a protein of the intermediate filament group present in most epithelial and parenchymal cells, is…”
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Nonsurviving Patients with Severe Traumatic Brain Injury Have Maintained High Serum sCD40L Levels by Lorente, Leonardo, Martín, María M., González-Rivero, Agustín F., Ramos, Luis, Argueso, Mónica, Cáceres, Juan J., Solé-Violán, Jordi, Jiménez, Alejandro, Borreguero-León, Juan M., García-Marín, Victor

“…Soluble cluster of differentiation 40 ligand (sCD40L) is a member of the tumor necrosis factor family with proinflamatory and procoagulant effects. A previous…”
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High Serum sCD40L Levels During the First Week of Malignant Middle Cerebral Artery Infarction and Mortality by Lorente, Leonardo, Martín, María M., González-Rivero, Agustín F., Sabatel, Rafael, Ramos, Luis, Argueso, Mónica, Cáceres, Juan J., Solé-Violán, Jordi, Alvarez-Castillo, Andrea, Jiménez, Alejandro, Borreguero-León, Juan M., García-Marín, Victor

“…Higher circulating soluble cluster of differentiation 40 ligand (sCD40L) levels at admission of an ischemic stroke have been found in nonsurvivor than in…”
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Higher serum caspase-cleaved cytokeratin-18 levels during the first week of sepsis diagnosis in non-survivor patients by Lorente, Leonardo, Martín, María M, Pérez-Cejas, Antonia, López, Raquel Ortiz, Ferreres, José, Solé-Violán, Jordi, Labarta, Lorenzo, Díaz, César, Palmero, Salomé, Buitrago, Manuel, Jiménez, Alejandro, Borreguero-León, Juan M

“…Caspase-cleaved cytokeratin (CCCK)-18 is a protein released into the blood during apoptosis. Higher circulating CCCK-18 concentrations have been found in…”
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Sustained high plasma plasminogen activator inhibitor-1 levels are associated with severity and mortality in septic patients by Lorente, Leonardo, Martín, María M, Borreguero-León, Juan M, Solé-Violán, Jordi, Ferreres, José, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro, Páramo, José A

“…Abstract Background Higher plasma plasminogen activator inhibitor-1 (PAI-1) levels have been reported in septic patients. However, some questions remain…”
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Serum caspase-3 levels are associated with early mortality in severe septic patients by Lorente, Leonardo, Martín, María M, Ferreres, José, Solé-Violán, Jordi, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro, Borreguero-León, Juan M

“…Abstract Objective Higher caspase-3 active have been found in lymphocytes of septic patients than of healthy controls. However, an association between serum…”
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Serum soluble CD40 Ligand levels are associated with severity and mortality of brain trauma injury patients by Lorente, Leonardo, Martín, María M, González-Rivero, Agustín F, Ramos, Luis, Argueso, Mónica, Cáceres, Juan J, Solé-Violán, Jordi, Serrano, Nicolás, Rodríguez, Sergio T, Jiménez, Alejandro, Borreguero-León, Juan M

“…Abstract Background Serum soluble CD40 Ligand (sCD40L) levels, which exhibit prothrombotic and proinflammatory properties, have not been studied in patients…”
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Serum melatonin levels are associated with mortality in severe septic patients by Lorente, Leonardo, Martín, María M, Abreu-González, Pedro, de la Cruz, Thais, Ferreres, José, Solé-Violán, Jordi, Labarta, Lorenzo, Díaz, César, Jiménez, Alejandro, Borreguero-León, Juan M

“…Abstract Objective Melatonin in septic patients has been scarcely explored and only in studies of small sample size (maximum 20 patients). Thus, the objective…”
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