Search Results - "Borrego, Lucia Bautista"
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Automated Insulin Delivery - Continuous Blood Glucose Control During Ex Situ Liver Perfusion
Published in IEEE transactions on biomedical engineering (01-04-2021)“…Objective: With the growing demand for livers in the field of transplantation, interest in normothermic ex situ machine perfusion (NMP) has increased in recent…”
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Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed
Published in Scientific reports (01-12-2020)“…Long-term perfusion of liver grafts outside of the body may enable repair of poor-quality livers that are currently declined for transplantation, mitigating…”
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Synthesis of coagulation factors during long‐term ex situ liver perfusion
Published in Artificial organs (01-02-2022)“…Robust viability assessment of grafts during normothermic liver perfusion is a prerequisite for organ use. Coagulation parameters are used commonly for liver…”
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An integrated perfusion machine preserves injured human livers for 1 week
Published in Nature biotechnology (01-02-2020)“…The ability to preserve metabolically active livers ex vivo for 1 week or more could allow repair of poor-quality livers that would otherwise be declined for…”
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Defatting of Human Livers during Long-Term ex situ Normothermic Perfusion. Novel Strategy to Rescue Discarded Organs for Transplantation
Published in Annals of surgery (27-07-2023)Get full text
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Long-term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-livers
Published in Annals of surgery (01-11-2021)“…OBJECTIVEThe aim of this study was to maintain long-term full function and viability of partial livers perfused ex situ for sufficient duration to enable ex…”
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Model Assisted Analysis of the Hepatic Arterial Buffer Response During Ex Vivo Porcine Liver Perfusion
Published in IEEE transactions on biomedical engineering (01-03-2020)“…Objective: The hepatic arterial buffer response is a well-known phenomenon in hepatic circulation, describing the response of hepatic arterial resistance to…”
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Bile formation in long-term ex situ perfused livers
Published in Surgery (01-04-2021)“…Long-term ex situ liver perfusion may rescue injured grafts. Little is known about bile flow during long-term perfusion. We report the development of a bile…”
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Reply to: Lactate measurements in an integrated perfusion machine for human livers
Published in Nature biotechnology (01-11-2020)Get full text
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Sources and prevention of graft infection during long‐term ex situ liver perfusion
Published in Transplant infectious disease (01-08-2021)“…Introduction The use of normothermic liver machine perfusion to repair injured grafts ex situ is an emerging topic of clinical importance. However, a major…”
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Observations and findings during the development of a subnormothermic/normothermic long‐term ex vivo liver perfusion machine
Published in Artificial organs (01-02-2023)“…Background Ex situliver machine perfusion at subnormothermic/normothermic temperature isincreasingly applied in the field of transplantation to store and…”
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Transplantation of a human liver following 3 days of ex situ normothermic preservation
Published in Nature biotechnology (01-11-2022)“…Current organ preservation methods provide a narrow window (usually <12 hours) to assess, transport and implant donor grafts for human transplantation. Here we…”
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Defatting of Human Livers During Long-Term e x situ Normothermic Perfusion: Novel Strategy to Rescue Discarded Organs for Transplantation
Published in Annals of surgery (01-11-2023)“…To develop a protocol for the defatting of steatotic liver grafts during long-term ex situ normothermic machine perfusion. Despite the alarming increase in…”
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Normalization of lipid oxidation defects arising from hypoxia early posthepatectomy prevents liver failure in mouse
Published in American journal of transplantation (01-02-2023)“…Surgical liver failure (SLF) develops when a marginal amount of hepatic mass is left after surgery, such as following excessive resection. SLF is the commonest…”
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Long-Term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-Livers
Published in Annals of surgery (29-07-2021)Get full text
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FDG-PET/CT: novel method for viability assessment of livers perfused ex vivo
Published in Nuclear medicine communications (18-03-2021)Get full text
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Mitochondrial injury during normothermic regional perfusion (NRP) and hypothermic oxygenated perfusion (HOPE) in a rodent model of DCD liver transplantation
Published in EBioMedicine (01-12-2023)“…Normothermic regional perfusion (NRP) and hypothermic-oxygenated-perfusion (HOPE), were both shown to improve outcomes after liver transplantation from donors…”
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FDG-PET/CT: novel method for viability assessment of livers perfused ex vivo
Published in Nuclear medicine communications (01-07-2021)“…Ex vivo liver machine perfusion is a promising option to rescue marginal liver grafts mitigating the donated organ shortage. Recently, a novel liver perfusion…”
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