Search Results - "Borrás, Francesc"
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Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections
Published in Scientific reports (30-11-2018)“…The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is the etiological agent of one of the most important swine diseases with a significant…”
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Serum-derived exosomes from non-viremic animals previously exposed to the porcine respiratory and reproductive virus contain antigenic viral proteins
Published in Veterinary research (Paris) (31-05-2016)“…PRRSV is the etiological agent of one of the most important swine diseases with a significant economic burden worldwide and limitations in vaccinology…”
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The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses
Published in Autophagy (01-01-2015)“…CD5L (CD5 molecule-like) is a secreted glycoprotein that participates in host response to bacterial infection. CD5L influences the monocyte inflammatory…”
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Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice
Published in PloS one (04-09-2013)“…Cell therapy with endothelial progenitor cells (EPCs) has emerged as a promising strategy to regenerate the brain after stroke. Here, we aimed to investigate…”
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Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Published in Journal of extracellular vesicles (01-01-2015)“…Plasma-derived vesicles hold a promising potential for use in biomedical applications. Two major challenges, however, hinder their implementation into…”
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Extracellular vesicle isolation methods: rising impact of size-exclusion chromatography
Published in Cellular and molecular life sciences : CMLS (01-06-2019)“…Extracellular vesicles (EVs) include a variety of nanosized vesicles released to the extracellular microenvironment by the vast majority of cells transferring…”
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Standardising the preanalytical reporting of biospecimens to improve reproducibility in extracellular vesicle research – A GEIVEX study
Published in Journal of extracellular biology (01-04-2023)“…The standardization of clinical studies using extracellular vesicles (EVs) has mainly focused on the procedures employed for their isolation and…”
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Size-Exclusion Chromatography-based isolation minimally alters Extracellular Vesicles’ characteristics compared to precipitating agents
Published in Scientific reports (19-09-2016)“…Extracellular vesicles (EVs) have become an attractive field among the scientific community. Yet, a major challenge is to define a consensus method for EVs…”
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HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?
Published in PLoS pathogens (01-03-2010)“…Exosomes are secreted cellular vesicles that can induce specific CD4(+) T cell responses in vivo when they interact with competent antigen-presenting cells…”
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Commonly used methods for extracellular vesicles’ enrichment: Implications in downstream analyses and use
Published in European journal of cell biology (01-06-2022)“…Extracellular vesicles (EVs) are becoming promising tools for clinical application, either as sources of disease-specific molecular signatures for the…”
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Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles
Published in Frontiers in immunology (06-06-2019)“…Mesenchymal stem or stromal cells (MSC) have proven immunomodulatory properties toward B cell activation and induce regulatory B cells (Breg), through a dual…”
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Extracellular vesicles, new actors in the search for biomarkers of dementias
Published in Neurobiology of aging (01-02-2019)“…Increased life expectancy impacts directly on the number of older people worldwide with the associated increase in neurodegenerative diseases. Besides their…”
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Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer's disease and dementia with Lewy bodies
Published in Translational neurodegeneration (04-10-2019)“…Because of the increasing life expectancy in our society, aging-related neurodegenerative disorders are one of the main issues in global health. Most of these…”
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14
A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles
Published in Scientific reports (12-09-2017)“…Most experimental approaches commonly employed for the characterization and quantitation of EVs are time consuming, require of specialized instrumentation and…”
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Comparative study of clinical grade human tolerogenic dendritic cells
Published in Journal of translational medicine (09-06-2011)“…The use of tolerogenic DCs is a promising therapeutic strategy for transplantation and autoimmune disorders. Immunomodulatory DCs are primarily generated from…”
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Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function
Published in Frontiers in immunology (28-08-2017)“…The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising tool for treatment of immune disease and organ transplantation…”
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Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine
Published in Theranostics (2017)“…Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases…”
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Comprehensive proteomic profiling of plasma-derived Extracellular Vesicles from dementia with Lewy Bodies patients
Published in Scientific reports (16-09-2019)“…Proteins and nucleic acids contained in extracellular vesicles (EVs) are considered a feasible source of putative biomarkers for physiological and pathological…”
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Microvesicles released from Giardia intestinalis disturb host-pathogen response in vitro
Published in European journal of cell biology (01-03-2017)“…Giardia intestinalis (G.I), is an anaerobic protozoan and the aetiological agent of giardiasis, a diarrhoea present worldwide and associated with poverty. G.I…”
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Stable antigen‐specific T‐cell hyporesponsiveness induced by tolerogenic dendritic cells from multiple sclerosis patients
Published in European journal of immunology (01-03-2012)“…Multiple sclerosis (MS) is a chronic demyelinating autoimmune disease of the central nervous system. Current therapies decrease the frequency of relapses and…”
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