Search Results - "Borovskaya, T G"

Evaluation of the Effect of Dibornol on the Level of DNA Damage in the DNA Comet Test In Vivo by Borovskaya, T. G., Vychuzhanina, A. V., Schemerova, Yu. A., Stremlina, L. A., Chukicheva, I. Yu, Kuchin, A. V., Goldberg, V. E., Dygai, A. M.

“…In male C57BL/6 mice (8-12 weeks) and male Wistar rats (12 weeks), the effect of dibornol (2,6-diisobornyl-4-methylphenol) on the level of spontaneous DNA…”
Get full text

Assessment of Ante- and Postnatal Development of the Offspring of Male Rats Crossed in Delayed Periods after Treatment with Methotrexate in Low Doses by Borovskaya, T. G., Bokhan, E. A., Vychuzhanina, A. V., Shchemerova, Yu.A., Goldberg, V. E.

“…We studied ante- and postnatal development of the offspring of intact female rats crossed with males injected with low doses of methotrexate 3 and 6 months…”
Get full text

Safety of the Russian antiviral drug Kagocel by T G Borovskaya

“…The review gives summarized information on the preclinical data and clinical trials evaluating the safety of the antiviral drug Kagocel. It notes that the…”
Get full text

Regenerative Potential of Granulocyte Colony-Stimulating Factor Immobilized by Using Electron-Beam Synthesis Nanotechnology in an Experimental Model of Ovarian Reserve Depletion by Borovskaya, T. G., Vychuzhanina, A. V., Ligacheva, A. A., Shchemerova, Yu.A., Sandrikina, L. A., Madonov, P. G., Rakitin, F. A., Goldberg, V. E., Dygai, A. M.

“…The pharmacological activity of granulocyte CSF (G-CSF) immobilized using electron-beam synthesis nanotechnology (imG-CSF) was evaluated in an experimental…”
Get full text

Experimental Evaluation of the Effectiveness of Isobornylphenols in the Model of Pathospermia and Their Effect on the Antioxidant—Prooxidant Balance of Male Germ Cells by Borovskaya, T. G., Vychuzhanina, A. V., Shchemerova, Yu. A., Buravlev, E. V., Chukicheva, I. Yu, Kuchin, A. V.

“…We studied the effect of antioxidants dibornol (2,6-diisobornyl-4-methylphenol) and its derivative (4-hydroxymethyl-2,6-diisobornylphenol), members of the…”
Get full text

Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential by Asiedu-Gyekye, I. J., Borovskaya, T. G., Poluektova, M. E., Vychuzhanina, А. V., Shchemerovа, Y. А., Kamalova, S. I., Grgoreva, V. A., Amoateng, P., Kukuia, K. E., Kwapong, A. A., Allotey Babington, L., Amponsah, S. K., N’guessan, B. B.

“…Unsweetened natural cocoa (UNCP) was evaluated for reproductive toxicity in rats. A preliminary genotoxic potential was evaluated by the DNA comet assay test…”
Get full text

Delayed Consequences of the Toxic Effect of Paclitaxel on the Testes of Prepubertal Rats and Their Correction with p-Tyrosol by Borovskaya, T. G., Grigor’eva, V. A., Shchemerova, Yu. A., Bokhan, E. A., Vychuzhanina, A. V., Kamalova, S. I., Goldberg, V. E.

“…Delayed gonadotoxic effects were revealed in outbred male sexually mature rats (SD) after exposure to paclitaxel in the prepubertal period, and the possibility…”
Get full text

Long-term effects of cytostatic agents on germ cells of testicular tissue (experimental study) by Borovskaya, T. G., Vychuzhanina, A. V., Shchemerova, Yu. A., Kseneva, S. I., Fomina, T. I., Bokhan, E. A., Goldberg, V. E.

“…Currently, cytostatic drugs are widely used not only in cancer treatment, but also in the treatment of autoimmune infammatory diseases. A favorable prognosis…”
Get full text

Evaluation of the Effect of p-Tyrosol on the Level of DNA Damage in the DNA Comet Assay In Vivo by Borovskaya, T. G., Vychuzhanina, A. V., Grigor’eva, V. A., Kollantay, O. V., Goldberg, V. E., Dygai, A. M.

“…The effect of p- tyrosol on the spontaneous level of DNA damage in the cells of the bone marrow, liver, kidney, and rectum of mice (series I) and on the…”
Get full text

Estimation of the Regenerative Potential of para-Tyrosol in the Model of Testicular Insufficiency Caused by Damage to Spermatogonial Stem Cells by Borovskaya, T. G., Grigor’eva, V. A., Shchemerova, Yu. A., Kamalova, S. I., Vychuzhanina, A. V., Krivova, N. A., Zaeva, O. B., Goldberg, V. E., Dygai, A. M.

“…The regenerative properties of p- tyrosol were investigated in a model of testicular insufficiency caused by a toxic effect on spermatogonial stem cells…”
Get full text

Experimental Evaluation of Long-Term Toxic Effects of Methotrexate on Male Reproductive System by Borovskaya, T. G., Shchemerova, Yu. A., Bokhan, E. A., Grigor’eva, V. A., Vychuzhanina, A. V., Poluektova, M. E., Goldberg, V. E., Dygai, A. M.

“…The morphological and functional state of the reproductive system was studied in male outbred rats (SD stock) and male F1(CBA×C57BL/6) mice after long-term (3…”
Get full text

Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia by Borovskaya, T. G., Kamalova, S. I., Krivova, N. A., Zaeva, O. B., Poluektova, M. E., Vychuzhanina, A. V., Grigor’eva, V. A., Plotnikov, M. B., Goldberg, V. E.

“…The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology, functions, and redox processes in the reproductive cells of male…”
Get full text

Protective Effect of Polysaccharides from Tussilago farfara L. on Bone Marrow Cells and Small Intestinal Epithelium Under Conditions of Polychemotherapy Evaluated by DNA Comet Assay by Safonova, E. A., Lopatina, K. A., Vychuzhanina, A. V., Mashanova, V. A., Razina, T. G., Borovskaya, T. G., Zueva, E. P., Gur’ev, A. M., Belousov, M. V.

“…Using DNA comet assay we found that polysaccharides from Tussilago farfara L . reduced the intensity of polychemotherapy-induced apoptosis and DNA damage in…”
Get full text

Stage of Offspring of Female Rats after Treatment with Cytostatics of Various Groups by Borovskaya, T. G, Perova, A. V, Pachomova, A. V, Poluektova, M. E, Gol'dberg, V. E

“…We examined the offspring of female rats that were mated with intact males in the delayed period after administration of cytostatic drugs Farmorubicin,…”
Get full text

Effectiveness of Phenolic Antioxidants in Experimental Model of Benign Prostatic Hyperplasia by Borovskaya, T. G., Kamalova, S. I., Grigor’eva, V. A., Poluektova, M. E., Vychuzhanina, A. V., Kuchin, A. V., Chukicheva, I. Yu, Buravlev, E. V., Fomina, T. I., Plotnikov, M. B., Goldberg, V. E., Dygai, A. M.

“…Experimental model of sulpiride-provoked benign prostatic hyperplasia was employed to comparatively assess the effect of phenolic antioxidants…”
Get full text

Morphological and functional state of rat ovaries in early and late periods after administration of platinum cytostatics by Borovskaya, T G, Goldberg, V E, Fomina, T I, Pakhomova, A V, Kseneva, S I, Poluektova, M E, Goldberg, E D

“…Experiments on Wistar rats showed that cisplatin and carboplatin induced similar morphological alterations in the ovaries. Both agents reduced the number of…”
Get full text

Evaluation of Kagocel Genotoxicity by Zhanataev, A. K., Borovskaya, T. G., Shcherbakova, B. S., Rudoi, B. A., Vychuzhanina, A. V., Grigor’eva, V. A., Kamalova, S. I., Durnev, A. D.

“…Antiviral drug Kagocel in concentrations of 0.0008, 0.004, 0.02, 0.1, 0.5, and 2.5 mg/ml with or without metabolic activation does not induce gene mutations in…”
Get full text

EXPERIMENTAL EVALUATION OF LONG-TERM ADVERSE SIDE EFFECTS OF CYTOSTATIC DRUGS ON FEMALE REPRODUCTIVE FUNCTION AND PHARMACOLOGICAL WAYS TO REDUCE THEM by Borovskaya, T. G., Goldberg, V. E., Poluektova, M. E., Vychuzhanina, A. V., Shchemerovа, Yu. A., Grigoreva, V. A., Ligacheva, A. A., Bokhan, E. A.

“…The purpose of the study was a comparative experimental assessment of long-term toxic effects of cytostatic drugs (epirubicin, etoposide, platidiam,…”
Get full text

IN VITRO ASSESSMENT OF LONG-TERM EFFECTS OF CYTOTOXIC DRUGS ON MALE REPRODUCTIVE FUNCTION by Borovskaya, T. G., Goldberg, V. E., Poluektova, M. E., Shchemerovа, Yu. A., Vychuzhanina, A. V., Grigoreva, V. A., Kollantay, O. V., Kamalova, S. I.

“…The purpose of the study was a comparative assessment of long-term toxic effects of cytotoxic drugs (anthracycline antibiotics, topoisomerase activity…”
Get full text

Experimental Analysis of the Efficacy of Dihydroquercetin on the Model of Chronic Nonbacterial Inflammation of the Prostatic Gland by Borovskaya, T. G., Kamalova, S. I., Polyektova, M. E., Mashanova, V. A., Vychuzhanina, A. V., Kseneva, S. I., Plotnikov, M. B., Goldberg, V. E.

“…We studied the efficiency of dihydroquercetin on the model of chronic nonbacterial inflammation of the prostatic gland in rats. It was found that…”
Get full text