Search Results - "Borodkina, A. V."

Reactive Oxygen Species Are Required for Human Mesenchymal Stem Cells to Initiate Proliferation after the Quiescence Exit by Borodkina, Aleksandra, Zemelko, V. I., Burova, Elena, Puzanov, M. V., Nikolsky, Nikolay, Shatrova, Alla, Zenin, V. V., Ivanova, Ju. S., Obidina, Ju. V., Smirnova, I. S., Pugovkina, N. A., Borisov, Ya. G., Lyublinskaya, O. G., Aksenov, N. D.

“…The present study focuses on the involvement of reactive oxygen species (ROS) in the process of mesenchymal stem cells “waking up” and entering the cell cycle…”
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"Social Life" of Senescent Cells: What Is SASP and Why Study It? by Borodkina, A V, Deryabin, P I, Giukova, A A, Nikolsky, N N

“…Cellular senescence was first described as a failure of normal human cells to divide indefinitely in culture. Until recently, the emphasis in the study of cell…”
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Senescent endometrial stromal cells transmit reactive oxygen species to the trophoblast-like cells and impair spreading of blastocyst-like spheroids by Deryabin, P I, Ivanova, J S, Borodkina, A V

“…Successful implantation requires a fine-tuned dialog between the invading embryo and the maternal endometrium. Recently, we discovered that premature…”
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Reduced Efficiency of DNA Repair and Antioxidant Defense Promotes the Accumulation of DNA Damage during Cell Senescence by Deryabin, P. I., Borodkina, A. V.

“…The accumulation of senescent cells within the organism positively correlates with age and is considered as one of the risk factors for an age-dependent…”
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PTEN Knockout Causes Premature Senescence of Human Endometrial Stromal Cells by Parfenova, P. S., Deryabin, P. I., Pozdnyakov, D. Yu, Borodkina, A. V.

“…One protective mechanism against neoplastic transformation of cells in response to oncogenic stimuli is cellular senescence. However, the ability of cells to…”
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To Find and Destroy: Identification and Elimination of Senescent Cells by Borodkina, A. V., Deryabin, P. I., Griukova, A. A., Nikolsky, N. N.

“…“Our oldness is a disease that has to be treated like any other one,”—this statement formulated about a hundred years ago seems to be of current interest in…”
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The role of p38 MAP-kinase in stress-induced senescence of human endometrium-derived mesenchymal stem cells by Borodkina, A. V., Shatrova, A. N., Nikolsky, N. N., Burova, E. B.

“…Our recent findings demonstrate that human endometrium-derived mesenchymal stem cells (hMESCs) respond to sublethal oxidative stress by stress-induced…”
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ROLE OF P38 MAP-KINASE IN THE STRESS-INDUCED SENESCENCE PROGRESSION OF HUMAN ENDOMETRIUM-DERIVED MESENCHYMAL STEM CELLS by Borodkina, A V, Shatrova, A N, Nikolsky, N N, Burova, E B

“…Our recent findings clearly demonstrate that human endometrium-derived mesenchymal stem cells (hMESCs) respond to the sublethal oxidative stress by the…”
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RELATIONSHIP BETWEEN p53/p21/Rb AND MAPK SIGNALING PATHWAYS IN HUMAN ENDOMETRIUM-DERIVED STEM CELLS UNDER OXIDATIVE STRESS by Deryabin, P I, Borodkina, A V, Nikolsky, N N, Burova, E B

“…Human endometrium-derived mesenchymal stem cells (hMESC) under the sublethal oxidative stress induced by H2O2 activate both p53/p21/Rb and p38MAPK/MAPKAPK-2…”
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Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells by Deryabin, P I, Borodkina, A V

“…Abstract STUDY QUESTION What are the consequences of endometrial stromal cell (EnSC) senescence for endometrial function? SUMMARY ANSWER Senescence of EnSC…”
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Stromal Cell Senescence Contributes to Impaired Endometrial Decidualization and Defective Interaction With Trophoblast Cells by Deryabin, P. I., Borodkina, A. V.

“…(Abstracted from Hum Reprod 2022;37:1505–1524) The term senescence refers to the cellular state wherein cells preserve viability and metabolic activity while…”
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The relationship between p53/p21/Rb and MAPK signaling pathways in human endometrium-derived stem cells under oxidative stress by Deryabin, P. I., Borodkina, A. V., Nikolsky, N. N., Burova, E. B.

“…Human endometrium-derived mesenchymal stem cells (hMESC) under the sublethal oxidative stress induced by H 2 O 2 activate both the p53/p21/Rb and p38/MAPKAPK-2…”
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Oxidative stress response of human fibroblasts and endometrial mesenchymal stem cells by Shatrova, A. N., Lyublinskaya, O. G., Borodkina, A. V., Burova, E. B.

“…Human mesenchymal stem cells are a promising cell source for tissue engineering. During transplantation, they may be subjected to oxidative stress due to…”
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OXIDATIVE STRESS-PROMOTED RESPONSES IN HUMAN ENDOMETRIAL STEM CELLS AND LUNG EMBRYONIC FIBROBLASTS by Shatrova, A N, Lyublinskaya, O G, Borodkina, A V, Burova, E B

“…Human mesenchymal stem cells are an attractive cell source for tissue engineering. During transplantation they may be subjected to oxidative stress due to…”
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Different protective mechanisms of human embryonic and endometrium-derived mesenchymal stem cells under oxidative stress by Borodkina, A. V., Shatrova, A. N., Pugovkina, N. A., Zemelko, V. I., Nikolsky, N. N., Burova, E. B.

“…Oxidative stress has been shown to cause either apoptosis or stress-induced premature senescence (SIPS) in different cell types. At present, it is generally…”
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Differences in defense mechanisms against oxidative stress in both human embryonic and endometrium-derived mesenchymal stem cells by Borodkina, A V, Shatrova, A N, Pugovkina, N A, Zemel'ko, V I, Nikol'skiĭ, N N, Burova, E B

“…Oxidative stress has been shown to induce either apoptosis or stress-induced premature senescence (SIPS) in different cell types. At present, it is generally…”
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Comparison of human endometrial stem cells and fibroblasts resistance to oxidative stress by Burova, E B, Liublinskaia, O G, Shatrova, A N, Borodkina, A V, Nikol'skiĭ, N N

“…The response of human endometrial stem cells (hESCs) to oxidative stress has been investigated by flow cytometry. Two terminally differentiated cell lines were…”
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