Search Results - "Borodinova, A A"
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Epigenetic Regulation as a Basis for Long-Term Changes in the Nervous System: In Search of Specificity Mechanisms
Published in Biochemistry (Moscow) (01-09-2020)“…Adaptive long-term changes in the functioning of nervous system (plasticity, memory) are not written in the genome, but are directly associated with the…”
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Plasticity of Response Properties of Mouse Visual Cortex Neurons Induced by Optogenetic Tetanization In Vivo
Published in Current issues in molecular biology (01-04-2024)“…Heterosynaptic plasticity, along with Hebbian homosynaptic plasticity, is an important mechanism ensuring the stable operation of learning neuronal networks…”
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Influence of histone deacetylases inhibitor sodium butyrate on hippocampal neuronal activity in vivo
Published in Neuroscience and behavioral physiology (01-06-2022)“…Epigenetic regulation plays an important role in cognitive brain functions. The increase in histone acetylation by histone deacetylase inhibitors, such as…”
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Neurogenetic Technologies for Research on the Mechanisms Maintaining Memory
Published in Neuroscience and behavioral physiology (01-10-2020)“…This article analyzes possible approaches to studies of the mechanisms maintaining memory at the level of long-term rearrangements of the level of expression…”
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In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model
Published in Redox biology (01-12-2021)“…Ischemic cerebral stroke is one of the leading causes of death and disability in humans. However, molecular processes underlying the development of this…”
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Role of atypical protein kinases in maintenance of long-term memory and synaptic plasticity
Published in Biochemistry (Moscow) (01-03-2017)“…Investigation of biochemical mechanisms underlying the long-term storage of information in nervous system is one of main problems of modern neurobiology. As a…”
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Differences in the Biological Functions of BDNF and proBDNF in the Central Nervous System
Published in Neuroscience and behavioral physiology (01-03-2017)“…Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed protein regulators of many biological processes in the central nervous system…”
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Use of Optical Probes for Visualizing Intracellular Calcium and Recording Action Potentials in Neurons
Published in Neuroscience and behavioral physiology (01-10-2022)“…To date, intracellular calcium reporters are the most commonly used optical probes for detecting neuron activity. Synthetic low molecular weight and…”
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Genetic Constructs for the Control of Astrocytes’ Activity
Published in Cells (Basel, Switzerland) (25-06-2021)“…In the current review, we aim to discuss the principles and the perspectives of using the genetic constructs based on AAV vectors to regulate astrocytes’…”
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Diversity of proBDNF and mBDNF functions in the central nervous system
Published in Zurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova (01-01-2016)“…Brain-derived neurotrophic factor (BDNF) is one of the major protein regulators of diverse biological functions in the nervous system. It is synthesized as a…”
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Both neuronal and non-neuronal acetylcholine take part in non-quantal acetylcholine release in the rat atrium
Published in Life sciences (1973) (27-11-2012)“…In mammalian myocardium acetylcholine (ACh), neurotransmitter which strikingly affects the cardiomyocytes, can be released from the neurons both via quantal…”
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Identification and Application of Gene Expression Signatures Associated with Lifespan Extension
Published in Cell metabolism (03-09-2019)“…Several pharmacological, dietary, and genetic interventions that increase mammalian lifespan are known, but general principles of lifespan extension remain…”
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Non-quantal release of acetylcholine from parasympathetic nerve terminals in the right atrium of rats
Published in Experimental physiology (01-02-2010)“…Acetylcholinesterase (AChE) inhibitors provoke typical cholinergic effects in the isolated right atrium of the rat due to the accumulation of acetylcholine…”
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Anion-selective channelrhodopsin expressed in neuronal cell culture and in vivo in murine brain: Light-induced inhibition of generation of action potentials
Published in Doklady. Biochemistry and biophysics (01-11-2015)“…Anionic channelrhodopsin slow ChloC was expressed in the culture of nerve cells and in vivo in mouse brain. We demonstrated ability of slow ChloC to suppress…”
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Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability
Published in Gene therapy (01-03-2024)“…Gene therapy offers a potential alternative to the surgical treatment of epilepsy, which affects millions of people and is pharmacoresistant in ~30% of cases…”
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Histone acetylation determines transcription of atypical protein kinases in rat neurons
Published in Scientific reports (13-03-2019)“…It is widely accepted that memory consolidation requires de-novo transcription of memory-related genes. Epigenetic modifications, particularly histone…”
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Nitric oxide modulates intensity of non-quantal acetylcholine release in myocardium of the right atrium of rat
Published in Biochemistry (Moscow). Supplement series A, Membrane and cell biology (01-10-2012)“…The main parasympathetic neurotransmitter acetylcholine (ACh) is released in the myocardium from the intramural postganglionic parasympathetic nerve endings…”
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Non‐quantal release of acetylcholine in rat atrial myocardium is inhibited by noradrenaline
Published in Experimental physiology (01-12-2013)“…New findings • What is the central question of this study? Is non‐quantal release of ACh in the heart regulated by noradrenaline or does it represent…”
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Noradrenergic regulation of non-quantal acetylcholine release from parasympathetic fibers in rat myocardium
Published in Autonomic neuroscience (01-10-2013)Get full text
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Effects of acetylcholinesterase inhibitor paraoxon denote the possibility of non-quantal acetylcholine release in myocardium of different vertebrates
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (2012)“…Effects of organophosphorous acetylcholinesterase inhibitor paraoxon were studied in the isolated atrial and ventricular myocardium preparations of a fish…”
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