Search Results - "Bornstein, Rafael"

Isolation and characterization of true mesenchymal stem cells derived from human term decidua capable of multilineage differentiation into all 3 embryonic layers by Macias, Maria I., MSc, Grande, Jesús, MD, Moreno, Ana, MSc, Domínguez, Irene, MSc, Bornstein, Rafael, MD, PhD, Flores, Ana I., PhD

“…Objective The objective of the study was to isolate and characterize a population of mesenchymal stem cells (MSCs) from human term placental membranes. Study…”
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A Modified Cord Blood Collection Method Achieves Sufficient Cell Levels for Transplantation in Most Adult Patients by Bornstein, Rafael, Flores, Aan I., Montalbán, M. Angeles, del Rey, Manuel J., de la Serna, Javier, Gilsanz, Florinda

“…Umbilical cord blood transplantation (UCBT) has been used increasingly in both pediatric and adult patients. The total nucleated cell (NC) dose infused is the…”
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Can fibrinolytic therapy be clinically useful in severe pneumonia caused by COVID-19? by Bornstein, Rafael, Páramo, José Antonio

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CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia by González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, José Luis, Ferrando, Adolfo A., Toribio, María L.

“…Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further…”
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Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis by Bravo, Beatriz, Gallego, Marta I, Flores, Ana I, Bornstein, Rafael, Puente-Bedia, Alba, Hernández, Javier, de la Torre, Paz, García-Zaragoza, Elena, Perez-Tavarez, Raquel, Grande, Jesús, Ballester, Alicia, Ballester, Sara

“…Multiple sclerosis is a widespread inflammatory demyelinating disease. Several immunomodulatory therapies are available, including interferon-β, glatiramer…”
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Human decidua-derived mesenchymal stromal cells differentiate into hepatic-like cells and form functional three-dimensional structures by Bornstein, Rafael, Macias, Maria I, de la Torre, Paz, Grande, Jesus, Flores, Ana I

“…Abstract Background aims Previously, we have shown that human decidua-derived mesenchymal stromal cells (DMSC) are mesenchymal stromal cells (MSC) with a…”
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A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARα-positive acute promyelocytic leukemia by SANZ, M. A, MARTIN, G, COLOMER, D, CHILL, C, RIVAS, C, GOMEZ, T, RIBERA, J. M, BORNSTEIN, R, ROMAN, J, CALASANZ, M. J, ARIAS, J, ALVAREZ, C, RAY, C, RAMOS, F, ESTEVE, J, GONZALEZ, M, DIAZ-MEDIAVILLA, J, BOLUFER, P, BARRAGAN, E, TEROL, M. J, GONZALEZ, J. D

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Consistency of the initial cell acquisition procedure is critical to the standardization of CD34+ cell enumeration by flow cytometry: results of a pairwise analysis of umbilical cord blood units and cryopreserved aliquots by Flores, Ana I., McKenna, David H., Montalbán, M. Angeles, De la Cruz, Javier, Wagner, John E., Bornstein, Rafael

“…BACKGROUND: The CD34+ cell content is a predictive factor for engraftment and survival after umbilical cord blood (UCB) transplantation. The high variability…”
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CSLaMAML-dependent Notch1 signaling controls T lineageaspecific IL-7RI- gene expression in early human thymopoiesis and leukemia by Gonzalez-Garcia, Sara, Garcia-PeydrA, Marina, Martin-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, Jose Luis, Ferrando, Adolfo A, Toribio, Maria L

“…Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further…”
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CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia by González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, José Luis, Ferrando, Adolfo A., Toribio, María L.

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A novel E2 box-GATA element modulates Cdc6 transcription during human cells polyploidization by Vilaboa, Nuria, Bermejo, Rodrigo, Martinez, Pilar, Bornstein, Rafael, Calés, Carmela

“…Cdc6 is a key regulator of the strict alternation of S and M phases during the mitotic cell cycle. In mammalian and plant cells that physiologically become…”
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Cord blood megakaryocytes do not complete maturation, as indicated by impaired establishment of endomitosis and low expression of G1/S cyclins upon thrombopoietin‐induced differentiation by Bornstein, Rafael, García‐Vela, José, Gilsanz, Florinda, Auray, Claude, Calés, Carmela

“…Cord blood (CB) has successfully been used as a stem cell source for haemopoietic reconstitution. However, a significant delay in platelet engraftment is…”
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Hypermethylation of the calcitonin gene in acute lymphoblastic leukaemia is associated with unfavourable clinical outcome by Roman, Jose, Castillejo, Juan Antonio, Jimenez, Antonio, Bornstein, Rafael, Gonzalez, Maria Gracia, Del Carmen Rodriguez, Maria, Barrios, Manuel, Maldonado, Juan, Torres, Antonio

“…We analysed calcitonin (CALC1) gene hypermethylation using semiquantitative differential polymerase chain reaction in 105 patients with adult (n = 49) and…”
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Hypermethylation of the calcitonin gene in acute lymphoblastic leukaemia is associated with unfavourable clincial outcome by Roman, Jose, Castillejo, Juan Antonio, Jimenez, Antonio, Bornstein, Rafael

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Cord blood megakaryocytes do not complete maturation, as indicated by impaired establishment of endomitosis and low expression of G1/S cylcins upon thombopoietin-induced by Bornstein, Rafael, Garcia-Vela, Jose, Gilsanz, Florinda, Auray, Claude, Cales, Carmela

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CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia by González-García, Sara, García-Peydró, Marina, Martín-Gayo, Enrique, Ballestar, Esteban, Esteller, Manel, Bornstein, Rafael, de la Pompa, José Luis, Ferrando, Adolfo A, Toribio, María L

“…Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further…”
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An association between viral genes and human oncogenic alterations: The adenovirus E1A induces the Ewing tumor fusion transcript EWS-FLI1 by Cajal, Santiago Ramon y, Sanchez-Prieto, Ricardo, Alava, Enrique de, Palomino, Teresa, Guinea, Juan, Fernandez, Victor, Cebrian, Silvia, LLeonart, Matilde, Cabello, Pablo, Martin, Pilar, Roman, Carlos San, Bornstein, Rafael, Pardo, Javier, Martinez, Ana, Diaz-Espada, Fernando, Barrios, Yve

“…Malignant transformation of human cells requires the accumulation of multiple genetic alterations, such as the activation of oncogenes and loss of function of…”
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Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols by Bolufer, P, Lo Coco, F, Grimwade, D, Barragan, E, Diverio, D, Cassinat, B, Chomienne, C, Gonzalez, M, Colomer, D, Gomez, MT, Marugan, I, Roman, J, Delgado, MD, Garcia-Marco, JA, Bornstein, R, Vizmanos, JL, Martinez, B, Jansen, J, Villegas, A, de Blas, JM, Cabello, P, Sanz, MA

“…Laboratory of Molecular Biology, Department of Clinical Pathology, Hospital Universitario La Fe, Valencia, Spain. bolufer_pas@gva.es BACKGROUND AND OBJECTIVES:…”
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Inconclusive presence of adenovirus sequences in human leukemias and lymphomas by Fernandez-Soria, Victor, Bornstein, Rafael, Forteza, Jeronimo, Parada, Carlos, Sanchez-Prieto, Ricado, Ramón y Cajal, Santiago

“…Adenoviruses are ubiquitous viruses related to human mild upper tract respiratory infections. Murine cells are semi-permissive to adenovirus replication, and…”
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A Modified AIDA Protocol With Anthracycline-Based Consolidation Results in High Antileukemic Efficacy and Reduced Toxicity in Newly Diagnosed PML/RAR∝-Positive Acute Promyelocytic Leukemia by Sanz, Miguel A., Martín, Guillermo, Rayón, Consuelo, Esteve, Jordi, González, Marcos, Díaz-Mediavilla, Joaquín, Bolufer, Pascual, Barragán, Eva, Terol, María J., González, José D., Colomer, Dolors, Chillón, Carmen, Rivas, Concha, Gómez, Teresa, Ribera, José M., Bornstein, Rafael, Román, José, Calasanz, María J., Arias, Jesus, Álvarez, Carmen, Ramos, Fernando, Debén, Guillermo

“…The Spanish PETHEMA group designed a protocol for newly diagnosed PML/RAR∝-positive acute promyelocytic leukemia (APL) in which induction and consolidation…”
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